| 2026-05-02 | PrestonvSouthamptonChampionship · England | 1–3 | Championship · England |
| 2026-04-28 | SouthamptonvIpswichChampionship · England | 2–2 | Championship · England |
| 2026-04-21 | SouthamptonvBristol CityChampionship · England | 2–2 | Championship · England |
| 2026-04-18 | SwanseavSouthamptonChampionship · England | 1–2 | Championship · England |
| 2026-04-14 | SouthamptonvBlackburnChampionship · England | 3–0 | Championship · England |
| 2026-04-11 | SouthamptonvDerbyChampionship · England | 2–1 | Championship · England |
| 2026-04-07 | WrexhamvSouthamptonChampionship · England | 1–5 | Championship · England |
| 2026-03-21 | SouthamptonvOxfordChampionship · England | 2–0 | Championship · England |
| 2026-03-18 | SouthamptonvNorwichChampionship · England | 1–0 | Championship · England |
| 2026-03-14 | CoventryvSouthamptonChampionship · England | 1–2 | Championship · England |
| 2026-03-11 | West BromvSouthamptonChampionship · England | 1–1 | Championship · England |
| 2026-02-28 | Sheffield WedsvSouthamptonChampionship · England | 1–3 | Championship · England |
| 2026-02-24 | SouthamptonvQPRChampionship · England | 5–0 | Championship · England |
| 2026-02-21 | SouthamptonvCharltonChampionship · England | 1–1 | Championship · England |
| 2026-02-10 | LeicestervSouthamptonChampionship · England | 3–4 | Championship · England |
| 2026-02-07 | SouthamptonvWatfordChampionship · England | 1–0 | Championship · England |
| 2026-01-31 | StokevSouthamptonChampionship · England | 0–2 | Championship · England |
| 2026-01-25 | PortsmouthvSouthamptonChampionship · England | 1–1 | Championship · England |
| 2026-01-21 | SouthamptonvSheffield UnitedChampionship · England | 1–0 | Championship · England |
| 2026-01-17 | SouthamptonvHullChampionship · England | 1–2 | Championship · England |
| 2026-01-04 | MiddlesbroughvSouthamptonChampionship · England | 4–0 | Championship · England |
| 2026-01-01 | SouthamptonvMillwallChampionship · England | 0–0 | Championship · England |
| 2025-12-29 | BirminghamvSouthamptonChampionship · England | 1–1 | Championship · England |
| 2025-12-26 | OxfordvSouthamptonChampionship · England | 2–1 | Championship · England |
| 2025-12-20 | SouthamptonvCoventryChampionship · England | 1–1 | Championship · England |
| 2025-12-13 | NorwichvSouthamptonChampionship · England | 2–1 | Championship · England |
| 2025-12-09 | SouthamptonvWest BromChampionship · England | 3–2 | Championship · England |
| 2025-12-06 | SouthamptonvBirminghamChampionship · England | 3–1 | Championship · England |
| 2025-11-29 | MillwallvSouthamptonChampionship · England | 3–2 | Championship · England |
| 2025-11-25 | SouthamptonvLeicesterChampionship · England | 3–0 | Championship · England |
| 2025-11-22 | CharltonvSouthamptonChampionship · England | 1–5 | Championship · England |
| 2025-11-08 | SouthamptonvSheffield WedsChampionship · England | 3–1 | Championship · England |
| 2025-11-05 | QPRvSouthamptonChampionship · England | 1–2 | Championship · England |
| 2025-11-01 | SouthamptonvPrestonChampionship · England | 0–2 | Championship · England |
| 2025-10-25 | BlackburnvSouthamptonChampionship · England | 2–1 | Championship · England |
| 2025-10-21 | Bristol CityvSouthamptonChampionship · England | 3–1 | Championship · England |
| 2025-10-18 | SouthamptonvSwanseaChampionship · England | 0–0 | Championship · England |
| 2025-10-04 | DerbyvSouthamptonChampionship · England | 1–1 | Championship · England |
| 2025-09-30 | Sheffield UnitedvSouthamptonChampionship · England | 1–2 | Championship · England |
| 2025-09-27 | SouthamptonvMiddlesbroughChampionship · England | 1–1 | Championship · England |
| 2025-09-20 | HullvSouthamptonChampionship · England | 3–1 | Championship · England |
| 2025-09-14 | SouthamptonvPortsmouthChampionship · England | 0–0 | Championship · England |
| 2025-08-30 | WatfordvSouthamptonChampionship · England | 2–2 | Championship · England |
| 2025-08-23 | SouthamptonvStokeChampionship · England | 1–2 | Championship · England |
| 2025-08-17 | IpswichvSouthamptonChampionship · England | 1–1 | Championship · England |
| 2025-08-09 | SouthamptonvWrexhamChampionship · England | 2–1 | Championship · England |
| 2025-05-25 | SouthamptonvArsenalPremier League · England | 1–2 | Premier League · England |
| 2025-05-18 | EvertonvSouthamptonPremier League · England | 2–0 | Premier League · England |
| 2025-05-10 | SouthamptonvMan CityPremier League · England | 0–0 | Premier League · England |
| 2025-05-03 | LeicestervSouthamptonPremier League · England | 2–0 | Premier League · England |