| 2022-08-14 | ChelseavTottenhamPremier League · England | 2–2 | Premier League · England |
| 2022-08-06 | TottenhamvSouthamptonPremier League · England | 4–1 | Premier League · England |
| 2022-05-22 | NorwichvTottenhamPremier League · England | 0–5 | Premier League · England |
| 2022-05-15 | TottenhamvBurnleyPremier League · England | 1–0 | Premier League · England |
| 2022-05-12 | TottenhamvArsenalPremier League · England | 3–0 | Premier League · England |
| 2022-05-07 | LiverpoolvTottenhamPremier League · England | 1–1 | Premier League · England |
| 2022-05-01 | TottenhamvLeicesterPremier League · England | 3–1 | Premier League · England |
| 2022-04-23 | BrentfordvTottenhamPremier League · England | 0–0 | Premier League · England |
| 2022-04-16 | TottenhamvBrightonPremier League · England | 0–1 | Premier League · England |
| 2022-04-09 | Aston VillavTottenhamPremier League · England | 0–4 | Premier League · England |
| 2022-04-03 | TottenhamvNewcastlePremier League · England | 5–1 | Premier League · England |
| 2022-03-20 | TottenhamvWest HamPremier League · England | 3–1 | Premier League · England |
| 2022-03-16 | BrightonvTottenhamPremier League · England | 0–2 | Premier League · England |
| 2022-03-12 | Man UnitedvTottenhamPremier League · England | 3–2 | Premier League · England |
| 2022-03-07 | TottenhamvEvertonPremier League · England | 5–0 | Premier League · England |
| 2022-02-26 | LeedsvTottenhamPremier League · England | 0–4 | Premier League · England |
| 2022-02-23 | BurnleyvTottenhamPremier League · England | 1–0 | Premier League · England |
| 2022-02-19 | Man CityvTottenhamPremier League · England | 2–3 | Premier League · England |
| 2022-02-13 | TottenhamvWolvesPremier League · England | 0–2 | Premier League · England |
| 2022-02-09 | TottenhamvSouthamptonPremier League · England | 2–3 | Premier League · England |
| 2022-01-23 | ChelseavTottenhamPremier League · England | 2–0 | Premier League · England |
| 2022-01-19 | LeicestervTottenhamPremier League · England | 2–3 | Premier League · England |
| 2022-01-01 | WatfordvTottenhamPremier League · England | 0–1 | Premier League · England |
| 2021-12-28 | SouthamptonvTottenhamPremier League · England | 1–1 | Premier League · England |
| 2021-12-26 | TottenhamvCrystal PalacePremier League · England | 3–0 | Premier League · England |
| 2021-12-19 | TottenhamvLiverpoolPremier League · England | 2–2 | Premier League · England |
| 2021-12-05 | TottenhamvNorwichPremier League · England | 3–0 | Premier League · England |
| 2021-12-02 | TottenhamvBrentfordPremier League · England | 2–0 | Premier League · England |
| 2021-11-21 | TottenhamvLeedsPremier League · England | 2–1 | Premier League · England |
| 2021-11-07 | EvertonvTottenhamPremier League · England | 0–0 | Premier League · England |
| 2021-10-30 | TottenhamvMan UnitedPremier League · England | 0–3 | Premier League · England |
| 2021-10-24 | West HamvTottenhamPremier League · England | 1–0 | Premier League · England |
| 2021-10-17 | NewcastlevTottenhamPremier League · England | 2–3 | Premier League · England |
| 2021-10-03 | TottenhamvAston VillaPremier League · England | 2–1 | Premier League · England |
| 2021-09-26 | ArsenalvTottenhamPremier League · England | 3–1 | Premier League · England |
| 2021-09-19 | TottenhamvChelseaPremier League · England | 0–3 | Premier League · England |
| 2021-09-11 | Crystal PalacevTottenhamPremier League · England | 3–0 | Premier League · England |
| 2021-08-29 | TottenhamvWatfordPremier League · England | 1–0 | Premier League · England |
| 2021-08-22 | WolvesvTottenhamPremier League · England | 0–1 | Premier League · England |
| 2021-08-15 | TottenhamvMan CityPremier League · England | 1–0 | Premier League · England |
| 2021-05-23 | LeicestervTottenhamPremier League · England | 2–4 | Premier League · England |
| 2021-05-19 | TottenhamvAston VillaPremier League · England | 1–2 | Premier League · England |
| 2021-05-16 | TottenhamvWolvesPremier League · England | 2–0 | Premier League · England |
| 2021-05-08 | LeedsvTottenhamPremier League · England | 3–1 | Premier League · England |
| 2021-05-02 | TottenhamvSheffield UnitedPremier League · England | 4–0 | Premier League · England |
| 2021-04-21 | TottenhamvSouthamptonPremier League · England | 2–1 | Premier League · England |
| 2021-04-16 | EvertonvTottenhamPremier League · England | 2–2 | Premier League · England |
| 2021-04-11 | TottenhamvMan UnitedPremier League · England | 1–3 | Premier League · England |
| 2021-04-04 | NewcastlevTottenhamPremier League · England | 2–2 | Premier League · England |
| 2021-03-21 | Aston VillavTottenhamPremier League · England | 0–2 | Premier League · England |