| 2025-11-08 | Minnesota UnitedvSeattle SoundersMLS · United States | 3–3 | MLS · United States |
| 2025-11-04 | Seattle SoundersvMinnesota UnitedMLS · United States | 4–2 | MLS · United States |
| 2025-10-28 | Minnesota UnitedvSeattle SoundersMLS · United States | 0–0 | MLS · United States |
| 2025-10-18 | New York CityvSeattle SoundersMLS · United States | 1–2 | MLS · United States |
| 2025-10-12 | Seattle SoundersvReal Salt LakeMLS · United States | 1–0 | MLS · United States |
| 2025-10-05 | Seattle SoundersvPortland TimbersMLS · United States | 1–0 | MLS · United States |
| 2025-09-28 | Seattle SoundersvVancouver WhitecapsMLS · United States | 2–2 | MLS · United States |
| 2025-09-22 | Austin FCvSeattle SoundersMLS · United States | 2–1 | MLS · United States |
| 2025-09-17 | Inter MiamivSeattle SoundersMLS · United States | 3–1 | MLS · United States |
| 2025-09-14 | Seattle SoundersvLos Angeles GalaxyMLS · United States | 2–2 | MLS · United States |
| 2025-08-25 | Seattle SoundersvSporting Kansas CityMLS · United States | 5–2 | MLS · United States |
| 2025-08-17 | Minnesota UnitedvSeattle SoundersMLS · United States | 1–0 | MLS · United States |
| 2025-08-11 | Los Angeles GalaxyvSeattle SoundersMLS · United States | 0–4 | MLS · United States |
| 2025-07-27 | Atlanta UtdvSeattle SoundersMLS · United States | 2–2 | MLS · United States |
| 2025-07-20 | Seattle SoundersvSan Jose EarthquakesMLS · United States | 3–2 | MLS · United States |
| 2025-07-17 | Seattle SoundersvColorado RapidsMLS · United States | 3–3 | MLS · United States |
| 2025-07-13 | Sporting Kansas CityvSeattle SoundersMLS · United States | 2–3 | MLS · United States |
| 2025-07-06 | Seattle SoundersvColumbus CrewMLS · United States | 1–1 | MLS · United States |
| 2025-06-29 | Seattle SoundersvAustin FCMLS · United States | 2–0 | MLS · United States |
| 2025-06-09 | Vancouver WhitecapsvSeattle SoundersMLS · United States | 3–0 | MLS · United States |
| 2025-06-01 | Seattle SoundersvMinnesota UnitedMLS · United States | 2–3 | MLS · United States |
| 2025-05-29 | Seattle SoundersvSan Diego FCMLS · United States | 1–0 | MLS · United States |
| 2025-05-24 | Seattle SoundersvFC DallasMLS · United States | 1–0 | MLS · United States |
| 2025-05-18 | Portland TimbersvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2025-05-15 | Los Angeles FCvSeattle SoundersMLS · United States | 4–0 | MLS · United States |
| 2025-05-11 | Houston DynamovSeattle SoundersMLS · United States | 1–3 | MLS · United States |
| 2025-05-04 | Seattle SoundersvSt. Louis CityMLS · United States | 4–1 | MLS · United States |
| 2025-04-27 | Colorado RapidsvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2025-04-20 | Seattle SoundersvNashville SCMLS · United States | 3–0 | MLS · United States |
| 2025-04-13 | FC DallasvSeattle SoundersMLS · United States | 0–1 | MLS · United States |
| 2025-04-06 | San Diego FCvSeattle SoundersMLS · United States | 3–0 | MLS · United States |
| 2025-03-30 | San Jose EarthquakesvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2025-03-23 | Seattle SoundersvHouston DynamoMLS · United States | 0–0 | MLS · United States |
| 2025-03-16 | St. Louis CityvSeattle SoundersMLS · United States | 1–0 | MLS · United States |
| 2025-03-08 | Seattle SoundersvLos Angeles FCMLS · United States | 5–2 | MLS · United States |
| 2025-03-01 | Real Salt LakevSeattle SoundersMLS · United States | 2–0 | MLS · United States |
| 2025-02-23 | Seattle SoundersvCharlotteMLS · United States | 2–2 | MLS · United States |