| 2022-11-12 | SampdoriavLecceSerie A · Italy | 0–2 | Serie A · Italy |
| 2022-11-09 | TorinovSampdoriaSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-11-06 | SampdoriavFiorentinaSerie A · Italy | 0–2 | Serie A · Italy |
| 2022-10-29 | IntervSampdoriaSerie A · Italy | 3–0 | Serie A · Italy |
| 2022-10-24 | CremonesevSampdoriaSerie A · Italy | 0–1 | Serie A · Italy |
| 2022-10-17 | SampdoriavRomaSerie A · Italy | 0–1 | Serie A · Italy |
| 2022-10-08 | BolognavSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-10-02 | SampdoriavMonzaSerie A · Italy | 0–3 | Serie A · Italy |
| 2022-09-17 | SpeziavSampdoriaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-09-10 | SampdoriavMilanSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-09-04 | VeronavSampdoriaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-08-31 | SampdoriavLazioSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-08-28 | SalernitanavSampdoriaSerie A · Italy | 4–0 | Serie A · Italy |
| 2022-08-22 | SampdoriavJuventusSerie A · Italy | 0–0 | Serie A · Italy |
| 2022-08-13 | SampdoriavAtalantaSerie A · Italy | 0–2 | Serie A · Italy |
| 2022-05-22 | IntervSampdoriaSerie A · Italy | 3–0 | Serie A · Italy |
| 2022-05-16 | SampdoriavFiorentinaSerie A · Italy | 4–1 | Serie A · Italy |
| 2022-05-07 | LaziovSampdoriaSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-04-30 | SampdoriavGenoaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-04-23 | VeronavSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-04-16 | SampdoriavSalernitanaSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-04-11 | BolognavSampdoriaSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-04-03 | SampdoriavRomaSerie A · Italy | 0–1 | Serie A · Italy |
| 2022-03-20 | VeneziavSampdoriaSerie A · Italy | 0–2 | Serie A · Italy |
| 2022-03-12 | SampdoriavJuventusSerie A · Italy | 1–3 | Serie A · Italy |
| 2022-03-05 | UdinesevSampdoriaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-02-28 | AtalantavSampdoriaSerie A · Italy | 4–0 | Serie A · Italy |
| 2022-02-19 | SampdoriavEmpoliSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-02-13 | MilanvSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-02-06 | SampdoriavSassuoloSerie A · Italy | 4–0 | Serie A · Italy |
| 2022-01-23 | SpeziavSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-01-15 | SampdoriavTorinoSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-01-09 | NapolivSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-01-06 | SampdoriavCagliariSerie A · Italy | 1–2 | Serie A · Italy |