| 2010-12-28 | PlymouthvNotts CountyLeague One · England | 1–1 | League One · England |
| 2010-12-11 | PlymouthvExeterLeague One · England | 2–0 | League One · England |
| 2010-11-23 | PlymouthvDag and RedLeague One · England | 2–1 | League One · England |
| 2010-11-20 | PlymouthvBrentfordLeague One · England | 1–2 | League One · England |
| 2010-11-13 | TranmerevPlymouthLeague One · England | 1–0 | League One · England |
| 2010-11-02 | PlymouthvBristol RvsLeague One · England | 3–1 | League One · England |
| 2010-10-30 | OldhamvPlymouthLeague One · England | 4–2 | League One · England |
| 2010-10-23 | PlymouthvHuddersfieldLeague One · England | 2–1 | League One · England |
| 2010-10-16 | Notts CountyvPlymouthLeague One · England | 2–0 | League One · England |
| 2010-10-09 | PlymouthvCharltonLeague One · England | 2–2 | League One · England |
| 2010-10-02 | PlymouthvHartlepoolLeague One · England | 0–1 | League One · England |
| 2010-09-28 | SwindonvPlymouthLeague One · England | 2–3 | League One · England |
| 2010-09-25 | RochdalevPlymouthLeague One · England | 1–1 | League One · England |
| 2010-09-21 | PlymouthvBrightonLeague One · England | 0–2 | League One · England |
| 2010-09-18 | PlymouthvSheffield WedsLeague One · England | 3–2 | League One · England |
| 2010-09-11 | ColchestervPlymouthLeague One · England | 1–1 | League One · England |
| 2010-08-28 | PlymouthvPeterboroLeague One · England | 0–3 | League One · England |
| 2010-08-21 | WalsallvPlymouthLeague One · England | 2–1 | League One · England |
| 2010-08-14 | PlymouthvCarlisleLeague One · England | 1–1 | League One · England |
| 2010-08-07 | SouthamptonvPlymouthLeague One · England | 0–1 | League One · England |
| 2010-05-02 | PlymouthvPeterboroChampionship · England | 1–2 | Championship · England |
| 2010-04-24 | Nott'm ForestvPlymouthChampionship · England | 3–0 | Championship · England |
| 2010-04-19 | PlymouthvNewcastleChampionship · England | 0–2 | Championship · England |
| 2010-04-10 | WatfordvPlymouthChampionship · England | 1–0 | Championship · England |
| 2010-04-05 | PlymouthvMiddlesbroughChampionship · England | 0–2 | Championship · England |
| 2010-04-03 | DoncastervPlymouthChampionship · England | 1–2 | Championship · England |
| 2010-03-30 | PlymouthvBarnsleyChampionship · England | 0–0 | Championship · England |
| 2010-03-27 | PlymouthvBlackpoolChampionship · England | 0–2 | Championship · England |
| 2010-03-23 | IpswichvPlymouthChampionship · England | 0–2 | Championship · England |
| 2010-03-20 | ScunthorpevPlymouthChampionship · England | 2–1 | Championship · England |
| 2010-03-16 | PlymouthvBristol CityChampionship · England | 3–2 | Championship · England |
| 2010-03-13 | CoventryvPlymouthChampionship · England | 1–1 | Championship · England |
| 2010-03-09 | QPRvPlymouthChampionship · England | 2–0 | Championship · England |
| 2010-03-06 | PlymouthvPrestonChampionship · England | 1–1 | Championship · England |
| 2010-02-27 | Sheffield UnitedvPlymouthChampionship · England | 4–3 | Championship · England |
| 2010-02-20 | PlymouthvLeicesterChampionship · England | 1–1 | Championship · England |
| 2010-02-16 | PlymouthvSwanseaChampionship · England | 1–1 | Championship · England |
| 2010-02-13 | BarnsleyvPlymouthChampionship · England | 1–3 | Championship · England |
| 2010-02-09 | ReadingvPlymouthChampionship · England | 2–1 | Championship · England |
| 2010-02-06 | PlymouthvWest BromChampionship · England | 0–1 | Championship · England |
| 2010-01-30 | Sheffield WedsvPlymouthChampionship · England | 2–1 | Championship · England |
| 2010-01-26 | PlymouthvDerbyChampionship · England | 1–0 | Championship · England |
| 2010-01-16 | PlymouthvCrystal PalaceChampionship · England | 0–1 | Championship · England |