| 2022-12-31 | NewcastlevLeedsPremier League · England | 0–0 | Premier League · England |
| 2022-12-26 | LeicestervNewcastlePremier League · England | 0–3 | Premier League · England |
| 2022-11-12 | NewcastlevChelseaPremier League · England | 1–0 | Premier League · England |
| 2022-11-06 | SouthamptonvNewcastlePremier League · England | 1–4 | Premier League · England |
| 2022-10-29 | NewcastlevAston VillaPremier League · England | 4–0 | Premier League · England |
| 2022-10-23 | TottenhamvNewcastlePremier League · England | 1–2 | Premier League · England |
| 2022-10-19 | NewcastlevEvertonPremier League · England | 1–0 | Premier League · England |
| 2022-10-16 | Man UnitedvNewcastlePremier League · England | 0–0 | Premier League · England |
| 2022-10-08 | NewcastlevBrentfordPremier League · England | 5–1 | Premier League · England |
| 2022-10-01 | FulhamvNewcastlePremier League · England | 1–4 | Premier League · England |
| 2022-09-17 | NewcastlevBournemouthPremier League · England | 1–1 | Premier League · England |
| 2022-09-03 | NewcastlevCrystal PalacePremier League · England | 0–0 | Premier League · England |
| 2022-08-31 | LiverpoolvNewcastlePremier League · England | 2–1 | Premier League · England |
| 2022-08-28 | WolvesvNewcastlePremier League · England | 1–1 | Premier League · England |
| 2022-08-21 | NewcastlevMan CityPremier League · England | 3–3 | Premier League · England |
| 2022-08-13 | BrightonvNewcastlePremier League · England | 0–0 | Premier League · England |
| 2022-08-06 | NewcastlevNott'm ForestPremier League · England | 2–0 | Premier League · England |
| 2022-05-22 | BurnleyvNewcastlePremier League · England | 1–2 | Premier League · England |
| 2022-05-16 | NewcastlevArsenalPremier League · England | 2–0 | Premier League · England |
| 2022-05-08 | Man CityvNewcastlePremier League · England | 5–0 | Premier League · England |
| 2022-04-30 | NewcastlevLiverpoolPremier League · England | 0–1 | Premier League · England |
| 2022-04-23 | NorwichvNewcastlePremier League · England | 0–3 | Premier League · England |
| 2022-04-20 | NewcastlevCrystal PalacePremier League · England | 1–0 | Premier League · England |
| 2022-04-17 | NewcastlevLeicesterPremier League · England | 2–1 | Premier League · England |
| 2022-04-08 | NewcastlevWolvesPremier League · England | 1–0 | Premier League · England |
| 2022-04-03 | TottenhamvNewcastlePremier League · England | 5–1 | Premier League · England |
| 2022-03-17 | EvertonvNewcastlePremier League · England | 1–0 | Premier League · England |
| 2022-03-13 | ChelseavNewcastlePremier League · England | 1–0 | Premier League · England |
| 2022-03-10 | SouthamptonvNewcastlePremier League · England | 1–2 | Premier League · England |
| 2022-03-05 | NewcastlevBrightonPremier League · England | 2–1 | Premier League · England |
| 2022-02-26 | BrentfordvNewcastlePremier League · England | 0–2 | Premier League · England |
| 2022-02-19 | West HamvNewcastlePremier League · England | 1–1 | Premier League · England |
| 2022-02-13 | NewcastlevAston VillaPremier League · England | 1–0 | Premier League · England |
| 2022-02-08 | NewcastlevEvertonPremier League · England | 3–1 | Premier League · England |
| 2022-01-22 | LeedsvNewcastlePremier League · England | 0–1 | Premier League · England |
| 2022-01-15 | NewcastlevWatfordPremier League · England | 1–1 | Premier League · England |