| 2022-11-13 | MainzvEin FrankfurtBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-11-09 | Schalke 04vMainzBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2022-11-05 | MainzvWolfsburgBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2022-10-29 | Bayern MunichvMainzBundesliga · Germany | 6–2 | Bundesliga · Germany |
| 2022-10-21 | MainzvFC KolnBundesliga · Germany | 5–0 | Bundesliga · Germany |
| 2022-10-15 | Werder BremenvMainzBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2022-10-08 | MainzvRB LeipzigBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-10-01 | FreiburgvMainzBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2022-09-16 | MainzvHerthaBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-09-10 | HoffenheimvMainzBundesliga · Germany | 4–1 | Bundesliga · Germany |
| 2022-09-04 | M'gladbachvMainzBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2022-08-27 | MainzvLeverkusenBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2022-08-20 | AugsburgvMainzBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2022-08-14 | MainzvUnion BerlinBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2022-08-06 | BochumvMainzBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2022-05-14 | MainzvEin FrankfurtBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2022-05-07 | HerthavMainzBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2022-04-30 | MainzvBayern MunichBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2022-04-22 | WolfsburgvMainzBundesliga · Germany | 5–0 | Bundesliga · Germany |
| 2022-04-16 | MainzvStuttgartBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2022-04-09 | FC KolnvMainzBundesliga · Germany | 3–2 | Bundesliga · Germany |
| 2022-04-06 | AugsburgvMainzBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2022-04-03 | M'gladbachvMainzBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-03-19 | MainzvBielefeldBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2022-03-16 | MainzvDortmundBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2022-02-26 | Union BerlinvMainzBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2022-02-18 | MainzvLeverkusenBundesliga · Germany | 3–2 | Bundesliga · Germany |
| 2022-02-12 | FreiburgvMainzBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2022-02-05 | MainzvHoffenheimBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2022-01-22 | Greuther FurthvMainzBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2022-01-15 | MainzvBochumBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2022-01-08 | RB LeipzigvMainzBundesliga · Germany | 4–1 | Bundesliga · Germany |