| 2010-12-28 | OxfordvMacclesfieldLeague Two · England | 2–1 | League Two · England |
| 2010-12-11 | MacclesfieldvGillinghamLeague Two · England | 2–4 | League Two · England |
| 2010-11-23 | MacclesfieldvCheltenhamLeague Two · England | 0–2 | League Two · England |
| 2010-11-20 | BradfordvMacclesfieldLeague Two · England | 0–1 | League Two · England |
| 2010-11-13 | MacclesfieldvAldershotLeague Two · England | 2–0 | League Two · England |
| 2010-11-02 | RotherhamvMacclesfieldLeague Two · England | 1–1 | League Two · England |
| 2010-10-30 | MacclesfieldvBurtonLeague Two · England | 2–1 | League Two · England |
| 2010-10-23 | BarnetvMacclesfieldLeague Two · England | 1–0 | League Two · England |
| 2010-10-16 | MacclesfieldvOxfordLeague Two · England | 3–2 | League Two · England |
| 2010-10-09 | LincolnvMacclesfieldLeague Two · England | 2–1 | League Two · England |
| 2010-10-02 | MacclesfieldvNorthamptonLeague Two · England | 2–0 | League Two · England |
| 2010-09-28 | CrewevMacclesfieldLeague Two · England | 1–1 | League Two · England |
| 2010-09-25 | TorquayvMacclesfieldLeague Two · England | 1–3 | League Two · England |
| 2010-09-18 | MacclesfieldvPort ValeLeague Two · England | 0–3 | League Two · England |
| 2010-09-11 | WycombevMacclesfieldLeague Two · England | 1–2 | League Two · England |
| 2010-09-04 | MacclesfieldvStockportLeague Two · England | 0–2 | League Two · England |
| 2010-08-28 | MacclesfieldvChesterfieldLeague Two · England | 1–1 | League Two · England |
| 2010-08-21 | AccringtonvMacclesfieldLeague Two · England | 3–0 | League Two · England |
| 2010-08-14 | MacclesfieldvShrewsburyLeague Two · England | 0–1 | League Two · England |
| 2010-08-07 | StevenagevMacclesfieldLeague Two · England | 2–2 | League Two · England |
| 2010-05-08 | LincolnvMacclesfieldLeague Two · England | 0–0 | League Two · England |
| 2010-05-01 | MacclesfieldvDarlingtonLeague Two · England | 0–2 | League Two · England |
| 2010-04-24 | TorquayvMacclesfieldLeague Two · England | 1–0 | League Two · England |
| 2010-04-17 | MacclesfieldvChesterfieldLeague Two · England | 2–0 | League Two · England |
| 2010-04-13 | MacclesfieldvBurtonLeague Two · England | 1–1 | League Two · England |
| 2010-04-10 | BarnetvMacclesfieldLeague Two · England | 1–2 | League Two · England |
| 2010-04-05 | BradfordvMacclesfieldLeague Two · England | 1–2 | League Two · England |
| 2010-04-03 | MacclesfieldvAldershotLeague Two · England | 1–1 | League Two · England |
| 2010-03-27 | MacclesfieldvCheltenhamLeague Two · England | 1–0 | League Two · England |
| 2010-03-23 | RotherhamvMacclesfieldLeague Two · England | 3–1 | League Two · England |
| 2010-03-20 | Dag and RedvMacclesfieldLeague Two · England | 3–1 | League Two · England |
| 2010-03-13 | MacclesfieldvBuryLeague Two · England | 2–0 | League Two · England |
| 2010-03-09 | AccringtonvMacclesfieldLeague Two · England | 1–1 | League Two · England |
| 2010-03-06 | HerefordvMacclesfieldLeague Two · England | 0–2 | League Two · England |
| 2010-03-02 | Notts CountyvMacclesfieldLeague Two · England | 1–0 | League Two · England |
| 2010-02-27 | MacclesfieldvRochdaleLeague Two · England | 0–1 | League Two · England |
| 2010-02-23 | GrimsbyvMacclesfieldLeague Two · England | 1–1 | League Two · England |
| 2010-02-20 | BournemouthvMacclesfieldLeague Two · England | 1–1 | League Two · England |
| 2010-02-13 | MacclesfieldvAccringtonLeague Two · England | 0–0 | League Two · England |
| 2010-02-09 | BuryvMacclesfieldLeague Two · England | 2–1 | League Two · England |
| 2010-02-06 | MacclesfieldvShrewsburyLeague Two · England | 0–1 | League Two · England |
| 2010-01-26 | MacclesfieldvMorecambeLeague Two · England | 2–2 | League Two · England |
| 2010-01-23 | Port ValevMacclesfieldLeague Two · England | 0–0 | League Two · England |
| 2010-01-20 | MacclesfieldvNorthamptonLeague Two · England | 0–2 | League Two · England |