| 2010-12-11 | TranmerevLeyton OrientLeague One · England | 1–2 | League One · England |
| 2010-11-23 | PeterborovLeyton OrientLeague One · England | 2–2 | League One · England |
| 2010-11-20 | Leyton OrientvBournemouthLeague One · England | 2–2 | League One · England |
| 2010-11-13 | Bristol RvsvLeyton OrientLeague One · England | 0–3 | League One · England |
| 2010-11-02 | ColchestervLeyton OrientLeague One · England | 3–2 | League One · England |
| 2010-10-30 | Leyton OrientvRochdaleLeague One · England | 2–1 | League One · England |
| 2010-10-23 | SwindonvLeyton OrientLeague One · England | 2–2 | League One · England |
| 2010-10-16 | Leyton OrientvHartlepoolLeague One · England | 1–0 | League One · England |
| 2010-10-09 | Sheffield WedsvLeyton OrientLeague One · England | 1–0 | League One · England |
| 2010-10-02 | OldhamvLeyton OrientLeague One · England | 1–1 | League One · England |
| 2010-09-28 | Leyton OrientvWalsallLeague One · England | 0–0 | League One · England |
| 2010-09-24 | Leyton OrientvBrentfordLeague One · England | 1–0 | League One · England |
| 2010-09-18 | Notts CountyvLeyton OrientLeague One · England | 3–2 | League One · England |
| 2010-09-11 | Leyton OrientvHuddersfieldLeague One · England | 1–2 | League One · England |
| 2010-09-04 | Dag and RedvLeyton OrientLeague One · England | 2–0 | League One · England |
| 2010-08-28 | Leyton OrientvExeterLeague One · England | 3–0 | League One · England |
| 2010-08-21 | SouthamptonvLeyton OrientLeague One · England | 1–1 | League One · England |
| 2010-08-13 | Leyton OrientvCharltonLeague One · England | 1–3 | League One · England |
| 2010-08-07 | YeovilvLeyton OrientLeague One · England | 2–1 | League One · England |
| 2010-05-08 | ColchestervLeyton OrientLeague One · England | 1–0 | League One · England |
| 2010-05-01 | Leyton OrientvWycombeLeague One · England | 2–0 | League One · England |
| 2010-04-24 | MillwallvLeyton OrientLeague One · England | 2–1 | League One · England |
| 2010-04-17 | Leyton OrientvStockportLeague One · England | 2–0 | League One · England |
| 2010-04-13 | Leyton OrientvNorwichLeague One · England | 2–1 | League One · England |
| 2010-04-10 | ExetervLeyton OrientLeague One · England | 0–0 | League One · England |
| 2010-04-05 | SouthamptonvLeyton OrientLeague One · England | 2–1 | League One · England |
| 2010-04-03 | Leyton OrientvHartlepoolLeague One · England | 1–3 | League One · England |
| 2010-03-27 | BrentfordvLeyton OrientLeague One · England | 1–0 | League One · England |
| 2010-03-20 | Leyton OrientvHuddersfieldLeague One · England | 0–2 | League One · England |
| 2010-03-13 | Leyton OrientvWalsallLeague One · England | 2–0 | League One · England |
| 2010-03-09 | OldhamvLeyton OrientLeague One · England | 2–0 | League One · England |
| 2010-03-06 | Milton Keynes DonsvLeyton OrientLeague One · England | 1–0 | League One · England |
| 2010-02-27 | Leyton OrientvSwindonLeague One · England | 0–0 | League One · England |
| 2010-02-23 | GillinghamvLeyton OrientLeague One · England | 1–1 | League One · England |
| 2010-02-20 | TranmerevLeyton OrientLeague One · England | 2–1 | League One · England |
| 2010-02-13 | Leyton OrientvLeedsLeague One · England | 1–1 | League One · England |
| 2010-02-06 | Leyton OrientvBrightonLeague One · England | 1–1 | League One · England |
| 2010-02-02 | Leyton OrientvBristol RvsLeague One · England | 5–0 | League One · England |
| 2010-01-30 | CarlislevLeyton OrientLeague One · England | 2–2 | League One · England |
| 2010-01-25 | CharltonvLeyton OrientLeague One · England | 0–1 | League One · England |
| 2010-01-19 | Leyton OrientvYeovilLeague One · England | 2–0 | League One · England |