| 2021-12-18 | LeedsvArsenalPremier League · England | 1–4 | Premier League · England |
| 2021-12-14 | Man CityvLeedsPremier League · England | 7–0 | Premier League · England |
| 2021-12-11 | ChelseavLeedsPremier League · England | 3–2 | Premier League · England |
| 2021-12-05 | LeedsvBrentfordPremier League · England | 2–2 | Premier League · England |
| 2021-11-30 | LeedsvCrystal PalacePremier League · England | 1–0 | Premier League · England |
| 2021-11-27 | BrightonvLeedsPremier League · England | 0–0 | Premier League · England |
| 2021-11-21 | TottenhamvLeedsPremier League · England | 2–1 | Premier League · England |
| 2021-11-07 | LeedsvLeicesterPremier League · England | 1–1 | Premier League · England |
| 2021-10-31 | NorwichvLeedsPremier League · England | 1–2 | Premier League · England |
| 2021-10-23 | LeedsvWolvesPremier League · England | 1–1 | Premier League · England |
| 2021-10-16 | SouthamptonvLeedsPremier League · England | 1–0 | Premier League · England |
| 2021-10-02 | LeedsvWatfordPremier League · England | 1–0 | Premier League · England |
| 2021-09-25 | LeedsvWest HamPremier League · England | 1–2 | Premier League · England |
| 2021-09-17 | NewcastlevLeedsPremier League · England | 1–1 | Premier League · England |
| 2021-09-12 | LeedsvLiverpoolPremier League · England | 0–3 | Premier League · England |
| 2021-08-29 | BurnleyvLeedsPremier League · England | 1–1 | Premier League · England |
| 2021-08-21 | LeedsvEvertonPremier League · England | 2–2 | Premier League · England |
| 2021-08-14 | Man UnitedvLeedsPremier League · England | 5–1 | Premier League · England |
| 2021-05-23 | LeedsvWest BromPremier League · England | 3–1 | Premier League · England |
| 2021-05-18 | SouthamptonvLeedsPremier League · England | 0–2 | Premier League · England |
| 2021-05-15 | BurnleyvLeedsPremier League · England | 0–4 | Premier League · England |
| 2021-05-08 | LeedsvTottenhamPremier League · England | 3–1 | Premier League · England |
| 2021-05-01 | BrightonvLeedsPremier League · England | 2–0 | Premier League · England |
| 2021-04-25 | LeedsvMan UnitedPremier League · England | 0–0 | Premier League · England |
| 2021-04-19 | LeedsvLiverpoolPremier League · England | 1–1 | Premier League · England |
| 2021-04-10 | Man CityvLeedsPremier League · England | 1–2 | Premier League · England |
| 2021-04-03 | LeedsvSheffield UnitedPremier League · England | 2–1 | Premier League · England |
| 2021-03-19 | FulhamvLeedsPremier League · England | 1–2 | Premier League · England |
| 2021-03-13 | LeedsvChelseaPremier League · England | 0–0 | Premier League · England |
| 2021-03-08 | West HamvLeedsPremier League · England | 2–0 | Premier League · England |
| 2021-02-27 | LeedsvAston VillaPremier League · England | 0–1 | Premier League · England |
| 2021-02-23 | LeedsvSouthamptonPremier League · England | 3–0 | Premier League · England |
| 2021-02-19 | WolvesvLeedsPremier League · England | 1–0 | Premier League · England |
| 2021-02-14 | ArsenalvLeedsPremier League · England | 4–2 | Premier League · England |
| 2021-02-08 | LeedsvCrystal PalacePremier League · England | 2–0 | Premier League · England |
| 2021-02-03 | LeedsvEvertonPremier League · England | 1–2 | Premier League · England |
| 2021-01-31 | LeicestervLeedsPremier League · England | 1–3 | Premier League · England |
| 2021-01-26 | NewcastlevLeedsPremier League · England | 1–2 | Premier League · England |
| 2021-01-16 | LeedsvBrightonPremier League · England | 0–1 | Premier League · England |
| 2021-01-02 | TottenhamvLeedsPremier League · England | 3–0 | Premier League · England |