| 2017-10-26 | Chicago FirevNew York Red BullsMLS · United States | 0–4 | MLS · United States |
| 2017-10-22 | Houston DynamovChicago FireMLS · United States | 3–0 | MLS · United States |
| 2017-10-15 | Chicago FirevPhiladelphia UnionMLS · United States | 3–2 | MLS · United States |
| 2017-10-01 | Chicago FirevNew York CityMLS · United States | 1–1 | MLS · United States |
| 2017-09-28 | San Jose EarthquakesvChicago FireMLS · United States | 1–4 | MLS · United States |
| 2017-09-24 | Philadelphia UnionvChicago FireMLS · United States | 3–1 | MLS · United States |
| 2017-09-17 | Chicago FirevDC UnitedMLS · United States | 3–0 | MLS · United States |
| 2017-09-09 | Chicago FirevNew York Red BullsMLS · United States | 1–1 | MLS · United States |
| 2017-09-03 | CF MontrealvChicago FireMLS · United States | 0–1 | MLS · United States |
| 2017-08-27 | Chicago FirevMinnesota UnitedMLS · United States | 1–2 | MLS · United States |
| 2017-08-20 | Chicago FirevToronto FCMLS · United States | 1–3 | MLS · United States |
| 2017-08-17 | CF MontrealvChicago FireMLS · United States | 3–0 | MLS · United States |
| 2017-08-13 | Columbus CrewvChicago FireMLS · United States | 3–1 | MLS · United States |
| 2017-08-06 | Chicago FirevNew England RevolutionMLS · United States | 4–1 | MLS · United States |
| 2017-07-30 | Sporting Kansas CityvChicago FireMLS · United States | 3–2 | MLS · United States |
| 2017-07-22 | New York CityvChicago FireMLS · United States | 2–1 | MLS · United States |
| 2017-07-06 | Portland TimbersvChicago FireMLS · United States | 2–2 | MLS · United States |
| 2017-07-02 | Chicago FirevVancouver WhitecapsMLS · United States | 4–0 | MLS · United States |
| 2017-06-25 | Chicago FirevOrlando CityMLS · United States | 4–0 | MLS · United States |
| 2017-06-18 | New England RevolutionvChicago FireMLS · United States | 1–2 | MLS · United States |
| 2017-06-10 | Chicago FirevAtlanta UtdMLS · United States | 2–0 | MLS · United States |
| 2017-06-05 | Orlando CityvChicago FireMLS · United States | 0–0 | MLS · United States |
| 2017-05-26 | Chicago FirevFC DallasMLS · United States | 2–1 | MLS · United States |
| 2017-05-20 | DC UnitedvChicago FireMLS · United States | 0–1 | MLS · United States |
| 2017-05-18 | Chicago FirevColorado RapidsMLS · United States | 3–0 | MLS · United States |
| 2017-05-14 | Chicago FirevSeattle SoundersMLS · United States | 4–1 | MLS · United States |
| 2017-05-07 | Los Angeles GalaxyvChicago FireMLS · United States | 2–2 | MLS · United States |
| 2017-04-30 | New York Red BullsvChicago FireMLS · United States | 2–1 | MLS · United States |
| 2017-04-22 | Toronto FCvChicago FireMLS · United States | 3–1 | MLS · United States |
| 2017-04-15 | Chicago FirevNew England RevolutionMLS · United States | 3–0 | MLS · United States |
| 2017-04-08 | Chicago FirevColumbus CrewMLS · United States | 1–0 | MLS · United States |
| 2017-04-01 | Chicago FirevCF MontrealMLS · United States | 2–2 | MLS · United States |
| 2017-03-18 | Atlanta UtdvChicago FireMLS · United States | 4–0 | MLS · United States |
| 2017-03-11 | Chicago FirevReal Salt LakeMLS · United States | 2–0 | MLS · United States |
| 2017-03-04 | Columbus CrewvChicago FireMLS · United States | 1–1 | MLS · United States |