| 2021-12-30 | Man UnitedvBurnleyPremier League · England | 3–1 | Premier League · England |
| 2021-12-12 | BurnleyvWest HamPremier League · England | 0–0 | Premier League · England |
| 2021-12-04 | NewcastlevBurnleyPremier League · England | 1–0 | Premier League · England |
| 2021-12-01 | WolvesvBurnleyPremier League · England | 0–0 | Premier League · England |
| 2021-11-20 | BurnleyvCrystal PalacePremier League · England | 3–3 | Premier League · England |
| 2021-11-06 | ChelseavBurnleyPremier League · England | 1–1 | Premier League · England |
| 2021-10-30 | BurnleyvBrentfordPremier League · England | 3–1 | Premier League · England |
| 2021-10-23 | SouthamptonvBurnleyPremier League · England | 2–2 | Premier League · England |
| 2021-10-16 | Man CityvBurnleyPremier League · England | 2–0 | Premier League · England |
| 2021-10-02 | BurnleyvNorwichPremier League · England | 0–0 | Premier League · England |
| 2021-09-25 | LeicestervBurnleyPremier League · England | 2–2 | Premier League · England |
| 2021-09-18 | BurnleyvArsenalPremier League · England | 0–1 | Premier League · England |
| 2021-09-13 | EvertonvBurnleyPremier League · England | 3–1 | Premier League · England |
| 2021-08-29 | BurnleyvLeedsPremier League · England | 1–1 | Premier League · England |
| 2021-08-21 | LiverpoolvBurnleyPremier League · England | 2–0 | Premier League · England |
| 2021-08-14 | BurnleyvBrightonPremier League · England | 1–2 | Premier League · England |
| 2021-05-23 | Sheffield UnitedvBurnleyPremier League · England | 1–0 | Premier League · England |
| 2021-05-19 | BurnleyvLiverpoolPremier League · England | 0–3 | Premier League · England |
| 2021-05-15 | BurnleyvLeedsPremier League · England | 0–4 | Premier League · England |
| 2021-05-10 | FulhamvBurnleyPremier League · England | 0–2 | Premier League · England |
| 2021-05-03 | BurnleyvWest HamPremier League · England | 1–2 | Premier League · England |
| 2021-04-25 | WolvesvBurnleyPremier League · England | 0–4 | Premier League · England |
| 2021-04-18 | Man UnitedvBurnleyPremier League · England | 3–1 | Premier League · England |
| 2021-04-11 | BurnleyvNewcastlePremier League · England | 1–2 | Premier League · England |
| 2021-04-04 | SouthamptonvBurnleyPremier League · England | 3–2 | Premier League · England |
| 2021-03-13 | EvertonvBurnleyPremier League · England | 1–2 | Premier League · England |
| 2021-03-06 | BurnleyvArsenalPremier League · England | 1–1 | Premier League · England |
| 2021-03-03 | BurnleyvLeicesterPremier League · England | 1–1 | Premier League · England |
| 2021-02-28 | TottenhamvBurnleyPremier League · England | 4–0 | Premier League · England |
| 2021-02-20 | BurnleyvWest BromPremier League · England | 0–0 | Premier League · England |
| 2021-02-17 | BurnleyvFulhamPremier League · England | 1–1 | Premier League · England |
| 2021-02-13 | Crystal PalacevBurnleyPremier League · England | 0–3 | Premier League · England |
| 2021-02-06 | BurnleyvBrightonPremier League · England | 1–1 | Premier League · England |
| 2021-02-03 | BurnleyvMan CityPremier League · England | 0–2 | Premier League · England |
| 2021-01-31 | ChelseavBurnleyPremier League · England | 2–0 | Premier League · England |
| 2021-01-27 | BurnleyvAston VillaPremier League · England | 3–2 | Premier League · England |
| 2021-01-21 | LiverpoolvBurnleyPremier League · England | 0–1 | Premier League · England |
| 2021-01-16 | West HamvBurnleyPremier League · England | 1–0 | Premier League · England |
| 2021-01-12 | BurnleyvMan UnitedPremier League · England | 0–1 | Premier League · England |