| 2021-12-18 | RB LeipzigvBielefeldBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2021-12-14 | BielefeldvBochumBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2021-12-11 | HerthavBielefeldBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2021-12-04 | BielefeldvFC KolnBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-11-27 | Bayern MunichvBielefeldBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-11-20 | BielefeldvWolfsburgBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2021-11-06 | StuttgartvBielefeldBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2021-10-30 | BielefeldvMainzBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2021-10-23 | BielefeldvDortmundBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2021-10-17 | AugsburgvBielefeldBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-10-03 | BielefeldvLeverkusenBundesliga · Germany | 0–4 | Bundesliga · Germany |
| 2021-09-25 | Union BerlinvBielefeldBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-09-18 | BielefeldvHoffenheimBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-09-12 | M'gladbachvBielefeldBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2021-08-28 | BielefeldvEin FrankfurtBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-08-21 | Greuther FurthvBielefeldBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-08-14 | BielefeldvFreiburgBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-05-22 | StuttgartvBielefeldBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2021-05-15 | BielefeldvHoffenheimBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-05-09 | HerthavBielefeldBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-04-25 | M'gladbachvBielefeldBundesliga · Germany | 5–0 | Bundesliga · Germany |
| 2021-04-20 | BielefeldvSchalke 04Bundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-04-17 | AugsburgvBielefeldBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-04-09 | BielefeldvFreiburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-04-03 | MainzvBielefeldBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2021-03-19 | BielefeldvRB LeipzigBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2021-03-14 | LeverkusenvBielefeldBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2021-03-10 | BielefeldvWerder BremenBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2021-03-07 | BielefeldvUnion BerlinBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-02-27 | DortmundvBielefeldBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2021-02-19 | BielefeldvWolfsburgBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2021-02-15 | Bayern MunichvBielefeldBundesliga · Germany | 3–3 | Bundesliga · Germany |
| 2021-01-31 | FC KolnvBielefeldBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2021-01-23 | BielefeldvEin FrankfurtBundesliga · Germany | 1–5 | Bundesliga · Germany |
| 2021-01-20 | BielefeldvStuttgartBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2021-01-16 | HoffenheimvBielefeldBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2021-01-10 | BielefeldvHerthaBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2021-01-02 | BielefeldvM'gladbachBundesliga · Germany | 0–1 | Bundesliga · Germany |