| 2022-10-30 | Los Angeles FCvAustin FCMLS · United States | 3–0 | MLS · United States |
| 2022-10-24 | Austin FCvFC DallasMLS · United States | 2–1 | MLS · United States |
| 2022-10-16 | Austin FCvReal Salt LakeMLS · United States | 2–2 | MLS · United States |
| 2022-10-09 | Austin FCvColorado RapidsMLS · United States | 1–1 | MLS · United States |
| 2022-10-02 | Vancouver WhitecapsvAustin FCMLS · United States | 2–0 | MLS · United States |
| 2022-09-18 | Austin FCvNashville SCMLS · United States | 1–1 | MLS · United States |
| 2022-09-15 | Austin FCvReal Salt LakeMLS · United States | 3–0 | MLS · United States |
| 2022-09-11 | Seattle SoundersvAustin FCMLS · United States | 3–0 | MLS · United States |
| 2022-09-04 | Nashville SCvAustin FCMLS · United States | 3–0 | MLS · United States |
| 2022-09-01 | Austin FCvPortland TimbersMLS · United States | 1–2 | MLS · United States |
| 2022-08-27 | Austin FCvLos Angeles FCMLS · United States | 4–1 | MLS · United States |
| 2022-08-21 | Minnesota UnitedvAustin FCMLS · United States | 2–1 | MLS · United States |
| 2022-08-14 | Austin FCvSporting Kansas CityMLS · United States | 4–3 | MLS · United States |
| 2022-08-07 | Austin FCvSan Jose EarthquakesMLS · United States | 3–3 | MLS · United States |
| 2022-07-31 | Sporting Kansas CityvAustin FCMLS · United States | 0–2 | MLS · United States |
| 2022-07-25 | Austin FCvNew York Red BullsMLS · United States | 3–4 | MLS · United States |
| 2022-07-17 | FC DallasvAustin FCMLS · United States | 1–1 | MLS · United States |
| 2022-07-13 | Austin FCvHouston DynamoMLS · United States | 3–1 | MLS · United States |
| 2022-07-10 | Atlanta UtdvAustin FCMLS · United States | 0–3 | MLS · United States |
| 2022-07-05 | Colorado RapidsvAustin FCMLS · United States | 2–3 | MLS · United States |
| 2022-07-01 | CharlottevAustin FCMLS · United States | 0–1 | MLS · United States |
| 2022-06-26 | Austin FCvFC DallasMLS · United States | 2–2 | MLS · United States |
| 2022-06-19 | CF MontrealvAustin FCMLS · United States | 0–1 | MLS · United States |
| 2022-05-29 | Los Angeles GalaxyvAustin FCMLS · United States | 4–1 | MLS · United States |
| 2022-05-23 | Austin FCvOrlando CityMLS · United States | 2–2 | MLS · United States |
| 2022-05-19 | Los Angeles FCvAustin FCMLS · United States | 1–2 | MLS · United States |
| 2022-05-15 | Real Salt LakevAustin FCMLS · United States | 2–1 | MLS · United States |
| 2022-05-09 | Austin FCvLos Angeles GalaxyMLS · United States | 0–1 | MLS · United States |
| 2022-04-30 | Houston DynamovAustin FCMLS · United States | 1–2 | MLS · United States |
| 2022-04-24 | Austin FCvVancouver WhitecapsMLS · United States | 3–0 | MLS · United States |
| 2022-04-17 | DC UnitedvAustin FCMLS · United States | 2–3 | MLS · United States |
| 2022-04-11 | Austin FCvMinnesota UnitedMLS · United States | 1–0 | MLS · United States |
| 2022-04-03 | San Jose EarthquakesvAustin FCMLS · United States | 2–2 | MLS · United States |
| 2022-03-20 | Austin FCvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2022-03-13 | Portland TimbersvAustin FCMLS · United States | 1–0 | MLS · United States |
| 2022-03-06 | Austin FCvInter MiamiMLS · United States | 5–1 | MLS · United States |
| 2022-02-26 | Austin FCvFC CincinnatiMLS · United States | 5–0 | MLS · United States |