| 2010-05-01 | BuyuksehyrvGalatasaraySüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2010-05-01 | Notts CountyvCheltenhamLeague Two · England | 5–0 | League Two · England |
| 2010-05-01 | Dundee UnitedvRangersPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2010-05-01 | LeverkusenvHerthaBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-05-01 | Albion RvsvStranraerLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2010-05-01 | FenerbahcevEskisehirsporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2010-05-01 | VillarrealvBarcelonaLa Liga · Spain | 1–4 | La Liga · Spain |
| 2010-05-01 | EspanolvValenciaLa Liga · Spain | 0–2 | La Liga · Spain |
| 2010-05-01 | AccringtonvChesterfieldLeague Two · England | 2–0 | League Two · England |
| 2010-05-01 | CharltonvLeedsLeague One · England | 1–0 | League One · England |
| 2010-05-01 | PiacenzavVicenzaSerie B · Italy | 1–1 | Serie B · Italy |
| 2010-05-01 | ModenavCittadellaSerie B · Italy | 2–1 | Serie B · Italy |
| 2010-05-01 | La CorunavZaragozaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2010-05-01 | NumanciavAlbaceteLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-05-01 | MilanvFiorentinaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-05-01 | TorinovGallipoliSerie B · Italy | 2–0 | Serie B · Italy |
| 2010-05-01 | GillinghamvSouthamptonLeague One · England | 2–1 | League One · England |
| 2010-05-01 | HuescavCartagenaLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2010-05-01 | HartlepoolvExeterLeague One · England | 1–1 | League One · England |
| 2010-05-01 | MortonvAyrChampionship · Scotland | 2–1 | Championship · Scotland |
| 2010-05-01 | PartickvQueen of SthChampionship · Scotland | 1–0 | Championship · Scotland |
| 2010-05-01 | PadovavSassuoloSerie B · Italy | 1–1 | Serie B · Italy |
| 2010-05-01 | CelticvMotherwellPremiership · Scotland | 4–0 | Premiership · Scotland |
| 2010-05-01 | AnkaragucuvTrabzonsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-05-01 | TottenhamvBoltonPremier League · England | 1–0 | Premier League · England |
| 2010-05-01 | FalkirkvSt MirrenPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2010-05-01 | XerezvAlmeriaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2010-05-01 | ParmavRomaSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-05-01 | Milton Keynes DonsvBrightonLeague One · England | 0–0 | League One · England |
| 2010-05-01 | FrosinonevCesenaSerie B · Italy | 0–2 | Serie B · Italy |
| 2010-05-01 | CeltavCadizLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-05-01 | ShrewsburyvMorecambeLeague Two · England | 2–3 | League Two · England |
| 2010-05-01 | Las PalmasvBetisLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-05-01 | LivingstonvEast StirlingLeague Two · Scotland | 1–0 | League Two · Scotland |
| 2010-05-01 | PortsmouthvWolvesPremier League · England | 3–1 | Premier League · England |
| 2010-05-01 | Bristol RvsvNorwichLeague One · England | 0–3 | League One · England |
| 2010-05-01 | StuttgartvMainzBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2010-05-01 | TranmerevMillwallLeague One · England | 2–0 | League One · England |
| 2010-05-01 | HamburgvNurnbergBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2010-05-01 | ClydevDumbartonLeague One · Scotland | 4–2 | League One · Scotland |
| 2010-05-01 | Leyton OrientvWycombeLeague One · England | 2–0 | League One · England |
| 2010-05-01 | GironavCordobaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-05-01 | BursasporvKayserisporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2010-05-01 | AlloavCowdenbeathLeague One · Scotland | 3–1 | League One · Scotland |
| 2010-05-01 | TenerifevSantanderLa Liga · Spain | 2–1 | La Liga · Spain |
| 2010-05-01 | RegginavAscoliSerie B · Italy | 1–2 | Serie B · Italy |
| 2010-05-01 | SociedadvVallecanoLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-05-01 | BrechinvStirlingLeague One · Scotland | 1–1 | League One · Scotland |
| 2010-05-01 | FC KolnvFreiburgBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2010-05-01 | RotherhamvCreweLeague Two · England | 0–0 | League Two · England |