| 2010-05-02 | MurciavCastellonLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-05-02 | AntalyasporvGaziantepsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-05-02 | LevantevHerculesLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-05-02 | AtalantavBolognaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-05-02 | Ath BilbaovMallorcaLa Liga · Spain | 1–3 | La Liga · Spain |
| 2010-05-02 | ChievovNapoliSerie A · Italy | 1–2 | Serie A · Italy |
| 2010-05-02 | NAC BredavTwenteEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2010-05-02 | KoblenzvKaiserslautern2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2010-05-02 | CagliarivUdineseSerie A · Italy | 2–2 | Serie A · Italy |
| 2010-05-02 | MaritimovSetubalPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2010-05-02 | SivassporvKasimpasaSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-05-02 | Greuther FurthvSt Pauli2. Bundesliga · Germany | 1–4 | 2. Bundesliga · Germany |
| 2010-05-02 | IpswichvSheffield UnitedChampionship · England | 0–3 | Championship · England |
| 2010-05-02 | FeyenoordvHeerenveenEredivisie · Netherlands | 6–2 | Eredivisie · Netherlands |
| 2010-05-02 | FulhamvWest HamPremier League · England | 3–2 | Premier League · England |
| 2010-05-02 | West BromvBarnsleyChampionship · England | 1–1 | Championship · England |
| 2010-05-02 | Hansa RostockvCottbus2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2010-05-02 | CataniavJuventusSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-05-02 | BlackpoolvBristol CityChampionship · England | 1–1 | Championship · England |
| 2010-05-02 | SunderlandvMan UnitedPremier League · England | 0–1 | Premier League · England |
| 2010-05-02 | AZ AlkmaarvPSV EindhovenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2010-05-02 | DiyarbakirsporvBesiktasSüper Lig · Turkey | 1–3 | Süper Lig · Turkey |
| 2010-05-01 | Airdrie UtdvDunfermlineChampionship · Scotland | 0–1 | Championship · Scotland |
| 2010-05-01 | LeccevAlbinoleffeSerie B · Italy | 2–1 | Serie B · Italy |
| 2010-05-01 | YeovilvOldhamLeague One · England | 3–0 | League One · England |
| 2010-05-01 | Bayern MunichvBochumBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2010-05-01 | ValladolidvGetafeLa Liga · Spain | 0–0 | La Liga · Spain |
| 2010-05-01 | Dag and RedvHerefordLeague Two · England | 2–1 | League Two · England |
| 2010-05-01 | MalagavSp GijonLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-05-01 | SalernitanavMantovaSerie B · Italy | 1–3 | Serie B · Italy |
| 2010-05-01 | BuryvTorquayLeague Two · England | 0–3 | League Two · England |
| 2010-05-01 | HibernianvHeartsPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2010-05-01 | Raith RvsvRoss CountyChampionship · Scotland | 4–1 | Championship · Scotland |
| 2010-05-01 | DortmundvWolfsburgBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-05-01 | CrotonevTriestinaSerie B · Italy | 2–0 | Serie B · Italy |
| 2010-05-01 | Man CityvAston VillaPremier League · England | 3–1 | Premier League · England |
| 2010-05-01 | HannovervM'gladbachBundesliga · Germany | 6–1 | Bundesliga · Germany |
| 2010-05-01 | ArbroathvEast FifeLeague One · Scotland | 2–2 | League One · Scotland |
| 2010-05-01 | SwindonvBrentfordLeague One · England | 3–2 | League One · England |
| 2010-05-01 | BirminghamvBurnleyPremier League · England | 2–1 | Premier League · England |
| 2010-05-01 | HuddersfieldvColchesterLeague One · England | 2–1 | League One · England |
| 2010-05-01 | StenhousemuirvPeterheadLeague One · Scotland | 1–1 | League One · Scotland |
| 2010-05-01 | SouthendvStockportLeague One · England | 2–1 | League One · England |
| 2010-05-01 | BradfordvNorthamptonLeague Two · England | 2–0 | League Two · England |
| 2010-05-01 | ElginvMontroseLeague Two · Scotland | 5–2 | League Two · Scotland |
| 2010-05-01 | RochdalevBurtonLeague Two · England | 1–2 | League Two · England |
| 2010-05-01 | KilmarnockvSt JohnstonePremiership · Scotland | 1–2 | Premiership · Scotland |
| 2010-05-01 | AldershotvLincolnLeague Two · England | 3–1 | League Two · England |
| 2010-05-01 | Inverness CvDundeeChampionship · Scotland | 1–0 | Championship · Scotland |
| 2010-05-01 | StokevEvertonPremier League · England | 0–0 | Premier League · England |