| 2016-09-11 | StandardvGenkPro League · Belgium | 2–0 | Pro League · Belgium |
| 2016-09-11 | Velez SarsfieldvRosario CentralLiga Profesional · Argentina | 2–0 | Liga Profesional · Argentina |
| 2016-09-11 | BolognavCagliariSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-09-11 | GianninavAtromitosSuper League · Greece | 3–0 | Super League · Greece |
| 2016-09-11 | New York Red BullsvDC UnitedMLS · United States | 2–2 | MLS · United States |
| 2016-09-11 | Pacos FerreiravEstorilPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2016-09-11 | MaritimovRio AvePrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2016-09-11 | RennesvCaenLigue 1 · France | 2–0 | Ligue 1 · France |
| 2016-09-11 | SionvThunSuper League · Switzerland | 1–0 | Super League · Switzerland |
| 2016-09-11 | NorrkopingvJonkopingsAllsvenskan · Sweden | 5–1 | Allsvenskan · Sweden |
| 2016-09-11 | Aston VillavNott'm ForestChampionship · England | 2–2 | Championship · England |
| 2016-09-11 | NicevMarseilleLigue 1 · France | 3–2 | Ligue 1 · France |
| 2016-09-11 | HuescavCordobaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2016-09-11 | TrabzonsporvOsmanlisporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2016-09-11 | New England RevolutionvNew York CityMLS · United States | 3–1 | MLS · United States |
| 2016-09-11 | AlcorconvGimnasticLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-09-11 | Estudiantes L.P.vSarmiento JuninLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-09-11 | La CorunavAth BilbaoLa Liga · Spain | 0–1 | La Liga · Spain |
| 2016-09-11 | SonderjyskevSilkeborgSuperliga · Denmark | 2–2 | Superliga · Denmark |
| 2016-09-11 | AtalantavTorinoSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-09-11 | Sport RecifevSanta CruzSerie A · Brazil | 5–3 | Serie A · Brazil |
| 2016-09-11 | ChievovLazioSerie A · Italy | 1–1 | Serie A · Italy |
| 2016-09-11 | Fortuna DusseldorfvGreuther Furth2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-09-11 | Ponte PretavAmerica MGSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2016-09-11 | SandhausenvKaiserslautern2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2016-09-11 | StabaekvRosenborgEliteserien · Norway | 0–2 | Eliteserien · Norway |
| 2016-09-11 | TromsovSogndalEliteserien · Norway | 2–0 | Eliteserien · Norway |
| 2016-09-11 | Chapecoense-SCvCoritibaSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2016-09-11 | NecaxavSantos LagunaLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2016-09-11 | AEKvXanthiSuper League · Greece | 4–1 | Super League · Greece |
| 2016-09-11 | Poli IasivFC BotosaniSuperliga · Romania | 0–1 | Superliga · Romania |
| 2016-09-11 | Go Ahead EaglesvRodaEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2016-09-11 | IndependientevGodoy CruzLiga Profesional · Argentina | 2–0 | Liga Profesional · Argentina |
| 2016-09-11 | San Jose EarthquakesvSeattle SoundersMLS · United States | 1–1 | MLS · United States |
| 2016-09-11 | PAOKvPanetolikosSuper League · Greece | 2–1 | Super League · Greece |
| 2016-09-11 | GentvLokerenPro League · Belgium | 3–0 | Pro League · Belgium |
| 2016-09-11 | Athletico-PRvInternacionalSerie A · Brazil | 2–1 | Serie A · Brazil |
| 2016-09-11 | RizesporvAkhisar BelediyesporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2016-09-11 | Guadalajara ChivasvChiapasLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2016-09-11 | Sp GijonvLeganesLa Liga · Spain | 2–1 | La Liga · Spain |
| 2016-09-11 | FCSBvAstraSuperliga · Romania | 1–0 | Superliga · Romania |
| 2016-09-11 | UNAM PumasvQueretaroLiga MX · Mexico | 4–1 | Liga MX · Mexico |
| 2016-09-11 | PescaravInterSerie A · Italy | 1–2 | Serie A · Italy |
| 2016-09-11 | JagielloniavWislaEkstraklasa · Poland | 2–1 | Ekstraklasa · Poland |
| 2016-09-11 | Newells Old BoysvTigreLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-09-11 | FeyenoordvDen HaagEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2016-09-11 | GironavAlmeriaLa Liga 2 · Spain | 3–3 | La Liga 2 · Spain |
| 2016-09-11 | AnderlechtvCharleroiPro League · Belgium | 3–2 | Pro League · Belgium |
| 2016-09-11 | Werder BremenvAugsburgBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2016-09-11 | Sp BragavBoavistaPrimeira Liga · Portugal | 3–0 | Primeira Liga · Portugal |