| 2010-05-09 | Dundee UnitedvHibernianPremiership · Scotland | 0–2 | Premiership · Scotland |
| 2010-05-09 | EvertonvPortsmouthPremier League · England | 1–0 | Premier League · England |
| 2010-05-09 | CadizvElcheLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-05-09 | Munich 1860vUnion Berlin2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-05-09 | WolvesvSunderlandPremier League · England | 2–1 | Premier League · England |
| 2010-05-09 | BielefeldvOberhausen2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-05-09 | EskisehirsporvSivassporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-05-09 | West HamvMan CityPremier League · England | 1–1 | Premier League · England |
| 2010-05-09 | Pacos FerreiravOlhanensePrimeira Liga · Portugal | 2–2 | Primeira Liga · Portugal |
| 2010-05-09 | ArsenalvFulhamPremier League · England | 4–0 | Premier League · England |
| 2010-05-09 | Fortuna DusseldorfvHansa Rostock2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2010-05-09 | KasimpasavDiyarbakirsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-05-09 | PalermovSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-05-09 | RomavCagliariSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-05-09 | IntervChievoSerie A · Italy | 4–3 | Serie A · Italy |
| 2010-05-09 | NapolivAtalantaSerie A · Italy | 2–0 | Serie A · Italy |
| 2010-05-09 | JuventusvParmaSerie A · Italy | 2–3 | Serie A · Italy |
| 2010-05-09 | BolognavCataniaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-05-09 | HullvLiverpoolPremier League · England | 0–0 | Premier League · England |
| 2010-05-09 | GenoavMilanSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-05-09 | UdinesevBariSerie A · Italy | 3–3 | Serie A · Italy |
| 2010-05-08 | BordeauxvSochauxLigue 1 · France | 2–0 | Ligue 1 · France |
| 2010-05-08 | VillarrealvValenciaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2010-05-08 | AuxerrevLensLigue 1 · France | 0–0 | Ligue 1 · France |
| 2010-05-08 | Le MansvParis SGLigue 1 · France | 1–0 | Ligue 1 · France |
| 2010-05-08 | AscolivLecceSerie B · Italy | 1–2 | Serie B · Italy |
| 2010-05-08 | La CorunavMallorcaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-05-08 | CheltenhamvAccringtonLeague Two · England | 1–1 | League Two · England |
| 2010-05-08 | SetubalvBelenensesPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2010-05-08 | WycombevGillinghamLeague One · England | 3–0 | League One · England |
| 2010-05-08 | MainzvSchalke 04Bundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2010-05-08 | ChesterfieldvBournemouthLeague Two · England | 2–1 | League Two · England |
| 2010-05-08 | BarnetvRochdaleLeague Two · England | 1–0 | League Two · England |
| 2010-05-08 | HoffenheimvStuttgartBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-05-08 | NurnbergvFC KolnBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2010-05-08 | MillwallvSwindonLeague One · England | 3–2 | League One · England |
| 2010-05-08 |  MonacovNancyLigue 1 · France | 2–1 | Ligue 1 · France |
| 2010-05-08 | TorquayvNotts CountyLeague Two · England | 0–0 | League Two · England |
| 2010-05-08 | WalsallvMilton Keynes DonsLeague One · England | 2–1 | League One · England |
| 2010-05-08 | CittadellavFrosinoneSerie B · Italy | 0–1 | Serie B · Italy |
| 2010-05-08 | Werder BremenvHamburgBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-05-08 | GallipolivCrotoneSerie B · Italy | 2–3 | Serie B · Italy |
| 2010-05-08 | Port ValevShrewsburyLeague Two · England | 1–1 | League Two · England |
| 2010-05-08 | GaziantepsporvGenclerbirligiSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-05-08 | SouthamptonvSouthendLeague One · England | 3–1 | League One · England |
| 2010-05-08 | BrentfordvHartlepoolLeague One · England | 0–0 | League One · England |
| 2010-05-08 | OldhamvCharltonLeague One · England | 0–2 | League One · England |
| 2010-05-08 | EspanolvOsasunaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2010-05-08 | BresciavAnconaSerie B · Italy | 3–0 | Serie B · Italy |
| 2010-05-08 | CrewevBradfordLeague Two · England | 0–1 | League Two · England |