| 2016-12-17 | Godoy CruzvGimnasia L.P.Liga Profesional · Argentina | 0–3 | Liga Profesional · Argentina |
| 2016-12-17 | OviedovCordobaLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2016-12-17 | CittadellavPisaSerie B · Italy | 1–0 | Serie B · Italy |
| 2016-12-17 | IndependientevBanfieldLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-12-17 | LeedsvBrentfordChampionship · England | 1–0 | Championship · England |
| 2016-12-17 | Bristol CityvPrestonChampionship · England | 1–2 | Championship · England |
| 2016-12-17 | ArbroathvElginLeague Two · Scotland | 3–2 | League Two · Scotland |
| 2016-12-17 | CracoviavLech PoznanEkstraklasa · Poland | 1–1 | Ekstraklasa · Poland |
| 2016-12-17 | ColchestervNotts CountyLeague Two · England | 2–1 | League Two · England |
| 2016-12-17 | GetafevValladolidLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2016-12-17 | SouthportvEastleighNational League · England | 4–3 | National League · England |
| 2016-12-17 | Estudiantes L.P.vDefensa y JusticiaLiga Profesional · Argentina | 1–2 | Liga Profesional · Argentina |
| 2016-12-17 | GironavGimnasticLa Liga 2 · Spain | 4–2 | La Liga 2 · Spain |
| 2016-12-17 | MechelenvWaasland-BeverenPro League · Belgium | 2–0 | Pro League · Belgium |
| 2016-12-17 | BuyuksehyrvTrabzonsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2016-12-17 | JagielloniavWisla PlockEkstraklasa · Poland | 1–2 | Ekstraklasa · Poland |
| 2016-12-17 | MortonvHibernianChampionship · Scotland | 1–1 | Championship · Scotland |
| 2016-12-17 | FCSBvPoli TimisoaraSuperliga · Romania | 1–0 | Superliga · Romania |
| 2016-12-17 | BerwickvMontroseLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2016-12-17 | LensvAjaccio GFCOLigue 2 · France | 2–1 | Ligue 2 · France |
| 2016-12-17 | Forest GreenvDover AthleticNational League · England | 1–1 | National League · England |
| 2016-12-17 | CardiffvBarnsleyChampionship · England | 3–4 | Championship · England |
| 2016-12-17 | GillinghamvMilton Keynes DonsLeague One · England | 1–0 | League One · England |
| 2016-12-17 | ToulousevNancyLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-12-17 | Austria ViennavMattersburgBundesliga · Austria | 2–0 | Bundesliga · Austria |
| 2016-12-17 | WycombevLeyton OrientLeague Two · England | 1–0 | League Two · England |
| 2016-12-17 | OostendevWaregemPro League · Belgium | 1–1 | Pro League · Belgium |
| 2016-12-17 | Pro VercellivSpalSerie B · Italy | 3–1 | Serie B · Italy |
| 2016-12-17 | EmpolivCagliariSerie A · Italy | 2–0 | Serie A · Italy |
| 2016-12-17 | ExetervMansfieldLeague Two · England | 2–0 | League Two · England |
| 2016-12-17 | PortsmouthvHartlepoolLeague Two · England | 0–0 | League Two · England |
| 2016-12-17 | Werder BremenvFC KolnBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2016-12-17 | ChesterfieldvBoltonLeague One · England | 1–0 | League One · England |
| 2016-12-17 | LivingstonvAirdrie UtdLeague One · Scotland | 2–0 | League One · Scotland |
| 2016-12-17 | KilmarnockvInverness CPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2016-12-17 | SwindonvFleetwood TownLeague One · England | 1–1 | League One · England |
| 2016-12-17 | LugovHuescaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-12-17 | TwentevAZ AlkmaarEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2016-12-17 | MorecambevCheltenhamLeague Two · England | 1–2 | League Two · England |
| 2016-12-17 | Schalke 04vFreiburgBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2016-12-17 | LatinavBresciaSerie B · Italy | 1–1 | Serie B · Italy |
| 2016-12-17 | VeriavXanthiSuper League · Greece | 0–4 | Super League · Greece |
| 2016-12-17 | AugsburgvM'gladbachBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2016-12-17 | St TruidenvGentPro League · Belgium | 3–1 | Pro League · Belgium |
| 2016-12-17 | ChestervAldershotNational League · England | 2–0 | National League · England |
| 2016-12-17 | MaidstonevNorth FerribyNational League · England | 1–2 | National League · England |
| 2016-12-17 | StenhousemuirvAlbion RvsLeague One · Scotland | 1–0 | League One · Scotland |
| 2016-12-16 | AjacciovNimesLigue 2 · France | 1–2 | Ligue 2 · France |
| 2016-12-16 | Erzgebirge AuevFortuna Dusseldorf2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2016-12-16 | HoffenheimvDortmundBundesliga · Germany | 2–2 | Bundesliga · Germany |