| 2008-12-14 | ThrasyvoulosvPanioniosSuper League · Greece | 1–3 | Super League · Greece |
| 2008-12-13 | LeverkusenvCottbusBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2008-12-13 | YeovilvStockportLeague One · England | 2–4 | League One · England |
| 2008-12-13 | StenhousemuirvAlbion RvsLeague Two · Scotland | 1–0 | League Two · Scotland |
| 2008-12-13 | SunderlandvWest BromPremier League · England | 4–0 | Premier League · England |
| 2008-12-13 | PisavParmaSerie B · Italy | 2–1 | Serie B · Italy |
| 2008-12-13 | PAOKvXanthiSuper League · Greece | 1–0 | Super League · Greece |
| 2008-12-13 | SochauxvCaenLigue 1 · France | 2–2 | Ligue 1 · France |
| 2008-12-13 | MantovavModenaSerie B · Italy | 2–2 | Serie B · Italy |
| 2008-12-13 | GrimsbyvShrewsburyLeague Two · England | 1–0 | League Two · England |
| 2008-12-13 | Le MansvBordeauxLigue 1 · France | 1–3 | Ligue 1 · France |
| 2008-12-13 | CeltavZaragozaLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2008-12-13 | PlymouthvQPRChampionship · England | 1–1 | Championship · England |
| 2008-12-13 | BolognavTorinoSerie A · Italy | 5–2 | Serie A · Italy |
| 2008-12-13 | SivassporvHacettepesporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2008-12-13 | HeerenveenvGraafschapEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2008-12-13 | Annan AthleticvBerwickLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2008-12-13 | PartickvAirdrie UtdChampionship · Scotland | 2–1 | Championship · Scotland |
| 2008-12-13 | GrossetovRiminiSerie B · Italy | 1–3 | Serie B · Italy |
| 2008-12-13 | Aston VillavBoltonPremier League · England | 4–2 | Premier League · England |
| 2008-12-13 | Queen of SthvDunfermlineChampionship · Scotland | 1–2 | Championship · Scotland |
| 2008-12-13 | BuryvPort ValeLeague Two · England | 3–0 | League Two · England |
| 2008-12-13 | East FifevStirlingLeague One · Scotland | 0–1 | League One · Scotland |
| 2008-12-13 | TriestinavLivornoSerie B · Italy | 1–1 | Serie B · Italy |
| 2008-12-13 | StokevFulhamPremier League · England | 0–0 | Premier League · England |
| 2008-12-13 | WaregemvMouscronPro League · Belgium | 2–1 | Pro League · Belgium |
| 2008-12-13 | BesiktasvAnkaragucuSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2008-12-13 | ElginvEast StirlingLeague Two · Scotland | 0–4 | League Two · Scotland |
| 2008-12-13 | ScunthorpevNorthamptonLeague One · England | 4–4 | League One · England |
| 2008-12-13 | GentvKortrijkPro League · Belgium | 1–1 | Pro League · Belgium |
| 2008-12-13 | NancyvGrenobleLigue 1 · France | 2–0 | Ligue 1 · France |
| 2008-12-13 | Leyton OrientvCheltenhamLeague One · England | 1–2 | League One · England |
| 2008-12-13 | Man CityvEvertonPremier League · England | 0–1 | Premier League · England |
| 2008-12-13 | ArbroathvPeterheadLeague One · Scotland | 4–0 | League One · Scotland |
| 2008-12-13 | WolvesvBarnsleyChampionship · England | 2–0 | Championship · England |
| 2008-12-13 | DumbartonvForfarLeague Two · Scotland | 3–0 | League Two · Scotland |
| 2008-12-13 | PrestonvBirminghamChampionship · England | 1–0 | Championship · England |
| 2008-12-13 | MiddlesbroughvArsenalPremier League · England | 1–1 | Premier League · England |
| 2008-12-13 | ClydevDundeeChampionship · Scotland | 1–0 | Championship · Scotland |
| 2008-12-13 | WalsallvMillwallLeague One · England | 1–2 | League One · England |
| 2008-12-13 | Ross CountyvLivingstonChampionship · Scotland | 1–4 | Championship · Scotland |
| 2008-12-13 | PeterborovOldhamLeague One · England | 2–2 | League One · England |
| 2008-12-13 | Dundee UnitedvRangersPremiership · Scotland | 2–2 | Premiership · Scotland |
| 2008-12-13 | BrentfordvBradfordLeague Two · England | 2–1 | League Two · England |
| 2008-12-13 | FeyenoordvAZ AlkmaarEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2008-12-13 | St JohnstonevMortonChampionship · Scotland | 1–0 | Championship · Scotland |
| 2008-12-13 | CittadellavBresciaSerie B · Italy | 2–0 | Serie B · Italy |
| 2008-12-13 | GenkvCharleroiPro League · Belgium | 1–0 | Pro League · Belgium |
| 2008-12-13 | Werder BremenvWolfsburgBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2008-12-13 | TubizevBergenPro League · Belgium | 2–1 | Pro League · Belgium |