| 2021-09-24 | West BromvQPRChampionship · England | 2–1 | Championship · England |
| 2021-09-24 | NancyvAmiensLigue 2 · France | 1–1 | Ligue 2 · France |
| 2021-09-24 | NiortvParis FCLigue 2 · France | 4–1 | Ligue 2 · France |
| 2021-09-24 | RegensburgvErzgebirge Aue2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |
| 2021-09-24 | Pau FCvDunkerqueLigue 2 · France | 1–2 | Ligue 2 · France |
| 2021-09-24 | CoventryvPeterboroChampionship · England | 3–0 | Championship · England |
| 2021-09-24 | WaterfordvDroghedaPremier Division · Ireland | 1–0 | Premier Division · Ireland |
| 2021-09-24 | JagielloniavLech PoznanEkstraklasa · Poland | 1–0 | Ekstraklasa · Poland |
| 2021-09-24 | Sp LisbonvMaritimoPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-09-24 | SochauxvAuxerreLigue 2 · France | 0–0 | Ligue 2 · France |
| 2021-09-24 | FC Rapid BucurestivFC VoluntariSuperliga · Romania | 0–1 | Superliga · Romania |
| 2021-09-24 | Shimizu S-PulsevVissel KobeJ1 League · Japan | 0–2 | J1 League · Japan |
| 2021-09-24 | Sarmiento JuninvVelez SarsfieldLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2021-09-24 | LecznavLechia GdanskEkstraklasa · Poland | 0–4 | Ekstraklasa · Poland |
| 2021-09-24 | AlmeriavTenerifeLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2021-09-24 | BohemiansvFinn HarpsPremier Division · Ireland | 1–2 | Premier Division · Ireland |
| 2021-09-24 | Derry CityvLongfordPremier Division · Ireland | 3–0 | Premier Division · Ireland |
| 2021-09-24 |  El Salvadorv GuatemalaFriendly | 0–2 | Friendly |
| 2021-09-24 | Sociedad BvHuescaLa Liga 2 · Spain | 0–2 | La Liga 2 · Spain |
| 2021-09-24 | Gil VicentevPortoPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2021-09-24 | Club BruggevOud-Heverlee LeuvenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-09-24 | Greuther FurthvBayern MunichBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2021-09-23 | New York Red BullsvNew York CityMLS · United States | 1–1 | MLS · United States |
| 2021-09-23 | CambuurvHeraclesEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2021-09-23 | Sao PaulovAmerica MGSerie A · Brazil | 0–0 | Serie A · Brazil |
| 2021-09-23 | KalmarvAIKAllsvenskan · Sweden | 1–1 | Allsvenskan · Sweden |
| 2021-09-23 | AlanyasporvKasimpasaSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2021-09-23 | VarbergvHackenAllsvenskan · Sweden | 1–1 | Allsvenskan · Sweden |
| 2021-09-23 | Chicago FirevNew England RevolutionMLS · United States | 2–3 | MLS · United States |
| 2021-09-23 | SionvLuzernSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2021-09-23 | GranadavSociedadLa Liga · Spain | 2–3 | La Liga · Spain |
| 2021-09-23 | TorinovLazioSerie A · Italy | 1–1 | Serie A · Italy |
| 2021-09-23 | IonikosvGianninaSuper League · Greece | 0–0 | Super League · Greece |
| 2021-09-23 | SampdoriavNapoliSerie A · Italy | 0–4 | Serie A · Italy |
| 2021-09-23 | HammarbyvGoteborgAllsvenskan · Sweden | 3–0 | Allsvenskan · Sweden |
| 2021-09-23 | AnderlechtvGentPro League · Belgium | 1–1 | Pro League · Belgium |
| 2021-09-23 | CadizvBarcelonaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2021-09-23 | LuganovGrasshoppersSuper League · Switzerland | 1–1 | Super League · Switzerland |
| 2021-09-23 | TwentevAZ AlkmaarEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2021-09-23 | RomavUdineseSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-09-23 | OsasunavBetisLa Liga · Spain | 1–3 | La Liga · Spain |
| 2021-09-23 | MjallbyvHalmstadAllsvenskan · Sweden | 0–0 | Allsvenskan · Sweden |
| 2021-09-23 | Volos NFCvAtromitosSuper League · Greece | 3–0 | Super League · Greece |
| 2021-09-23 | FenerbahcevGiresunsporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2021-09-23 | MonterreyvTolucaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2021-09-23 | Inter MiamivNashville SCMLS · United States | 1–5 | MLS · United States |
| 2021-09-23 | KonyasporvTrabzonsporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2021-09-22 | TernanavParmaSerie B · Italy | 3–1 | Serie B · Italy |
| 2021-09-22 | GaziantepvBuyuksehyrSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2021-09-22 | LillevReimsLigue 1 · France | 2–1 | Ligue 1 · France |