| 2010-08-17 | BoulognevNimesLigue 2 · France | 2–1 | Ligue 2 · France |
| 2010-08-17 | VannesvLavalLigue 2 · France | 2–1 | Ligue 2 · France |
| 2010-08-17 | Newport CountyvTamworthNational League · England | 1–1 | National League · England |
| 2010-08-17 | Eastbourne BoroughvHayes & YeadingNational League · England | 5–0 | National League · England |
| 2010-08-16 | MetzvTroyesLigue 2 · France | 0–1 | Ligue 2 · France |
| 2010-08-16 | OlhanensevGuimaraesPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2010-08-16 | Man UnitedvNewcastlePremier League · England | 3–0 | Premier League · England |
| 2010-08-16 | BuyuksehyrvKayserisporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2010-08-16 | BursasporvKonyasporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-08-15 | GenkvCharleroiPro League · Belgium | 5–0 | Pro League · Belgium |
| 2010-08-15 | Willem IIvNijmegenEredivisie · Netherlands | 3–5 | Eredivisie · Netherlands |
| 2010-08-15 | BordeauxvToulouseLigue 1 · France | 1–2 | Ligue 1 · France |
| 2010-08-15 | FenerbahcevAntalyasporSüper Lig · Turkey | 4–0 | Süper Lig · Turkey |
| 2010-08-15 | Beira MarvLeiriaPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2010-08-15 | MotherwellvHibernianPremiership · Scotland | 2–3 | Premiership · Scotland |
| 2010-08-15 | Rio AvevNacionalPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2010-08-15 | Nott'm ForestvLeedsChampionship · England | 1–1 | Championship · England |
| 2010-08-15 | Den HaagvRodaEredivisie · Netherlands | 1–3 | Eredivisie · Netherlands |
| 2010-08-15 | BenficavAcademicaPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2010-08-15 | CaenvLyonLigue 1 · France | 3–2 | Ligue 1 · France |
| 2010-08-15 | UtrechtvNAC BredaEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2010-08-15 | KarabuksporvManisasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2010-08-15 | LiverpoolvArsenalPremier League · England | 1–1 | Premier League · England |
| 2010-08-15 | LillevParis SGLigue 1 · France | 0–0 | Ligue 1 · France |
| 2010-08-15 | ExcelsiorvFeyenoordEredivisie · Netherlands | 3–2 | Eredivisie · Netherlands |
| 2010-08-15 | Cercle BruggevClub BruggePro League · Belgium | 3–1 | Pro League · Belgium |
| 2010-08-15 | AnkaragucuvTrabzonsporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2010-08-14 | ChelseavWest BromPremier League · England | 6–0 | Premier League · England |
| 2010-08-14 | AldershotvSouthendLeague Two · England | 1–0 | League Two · England |
| 2010-08-14 | Ross CountyvFalkirkChampionship · Scotland | 0–1 | Championship · Scotland |
| 2010-08-14 | YorkvKidderminsterNational League · England | 1–2 | National League · England |
| 2010-08-14 | HartlepoolvSwindonLeague One · England | 2–2 | League One · England |
| 2010-08-14 | PSV EindhovenvGraafschapEredivisie · Netherlands | 6–0 | Eredivisie · Netherlands |
| 2010-08-14 | IpswichvBurnleyChampionship · England | 1–1 | Championship · England |
| 2010-08-14 | Queens ParkvClydeLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2010-08-14 | CheltenhamvCreweLeague Two · England | 3–2 | League Two · England |
| 2010-08-14 | LincolnvTorquayLeague Two · England | 0–2 | League Two · England |
| 2010-08-14 | MacclesfieldvShrewsburyLeague Two · England | 0–1 | League Two · England |
| 2010-08-14 | BucasporvBesiktasSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2010-08-14 | RangersvKilmarnockPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2010-08-14 | NavalvPortoPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2010-08-14 | BerwickvElginLeague Two · Scotland | 6–2 | League Two · Scotland |
| 2010-08-14 | PortsmouthvReadingChampionship · England | 1–1 | Championship · England |
| 2010-08-14 | Pacos FerreiravSp LisbonPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-08-14 | SwanseavPrestonChampionship · England | 4–0 | Championship · England |
| 2010-08-14 | LeicestervMiddlesbroughChampionship · England | 0–0 | Championship · England |
| 2010-08-14 | Airdrie UtdvAyrLeague One · Scotland | 2–2 | League One · Scotland |
| 2010-08-14 | AlloavEast FifeLeague One · Scotland | 3–2 | League One · Scotland |
| 2010-08-14 | LutonvAltrinchamNational League · England | 2–1 | National League · England |
| 2010-08-14 | ColchestervSheffield WedsLeague One · England | 1–1 | League One · England |