| 2010-08-28 | ElchevRecreativoLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-08-28 | ArbroathvEast StirlingLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2010-08-28 | WolvesvNewcastlePremier League · England | 1–1 | Premier League · England |
| 2010-08-28 | Inverness CvHamiltonPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2010-08-28 | DoncastervHullChampionship · England | 3–1 | Championship · England |
| 2010-08-28 | HerefordvRotherhamLeague Two · England | 0–1 | League Two · England |
| 2010-08-28 | StockportvShrewsburyLeague Two · England | 0–4 | League Two · England |
| 2010-08-28 | LevantevSevillaLa Liga · Spain | 1–4 | La Liga · Spain |
| 2010-08-28 | Dag and RedvTranmereLeague One · England | 2–2 | League One · England |
| 2010-08-28 | Cercle BruggevLokerenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2010-08-28 | ChelseavStokePremier League · England | 2–0 | Premier League · England |
| 2010-08-28 | VicenzavPortogruaroSerie B · Italy | 4–1 | Serie B · Italy |
| 2010-08-28 | MalagavValenciaLa Liga · Spain | 1–3 | La Liga · Spain |
| 2010-08-28 | IraklisvOlympiakosSuper League · Greece | 2–1 | Super League · Greece |
| 2010-08-28 | SienavRegginaSerie B · Italy | 2–1 | Serie B · Italy |
| 2010-08-28 | MansfieldvCambridgeNational League · England | 1–0 | National League · England |
| 2010-08-28 | BucasporvGenclerbirligiSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2010-08-28 | SouthportvFleetwood TownNational League · England | 1–0 | National League · England |
| 2010-08-28 | St EtiennevLensLigue 1 · France | 3–1 | Ligue 1 · France |
| 2010-08-28 | Union BerlinvGreuther Furth2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2010-08-28 | NAC BredavVVV VenloEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2010-08-28 | StirlingvDunfermlineChampionship · Scotland | 1–5 | Championship · Scotland |
| 2010-08-28 | StandardvKortrijkPro League · Belgium | 1–0 | Pro League · Belgium |
| 2010-08-28 | CheltenhamvBurtonLeague Two · England | 2–1 | League Two · England |
| 2010-08-28 | Milton Keynes DonsvSwindonLeague One · England | 2–1 | League One · England |
| 2010-08-28 | Queen of SthvRoss CountyChampionship · Scotland | 3–0 | Championship · Scotland |
| 2010-08-28 | RodavHeraclesEredivisie · Netherlands | 4–2 | Eredivisie · Netherlands |
| 2010-08-28 | NacionalvGuimaraesPrimeira Liga · Portugal | 1–3 | Primeira Liga · Portugal |
| 2010-08-28 | BrentfordvRochdaleLeague One · England | 1–3 | League One · England |
| 2010-08-28 | NijmegenvHeerenveenEredivisie · Netherlands | 2–2 | Eredivisie · Netherlands |
| 2010-08-28 |  Saint Luciav MartiniqueFriendly | 1–1 | Friendly |
| 2010-08-28 | Leyton OrientvExeterLeague One · England | 3–0 | League One · England |
| 2010-08-28 | XerezvCartagenaLa Liga 2 · Spain | 1–4 | La Liga 2 · Spain |
| 2010-08-28 | BarnsleyvMiddlesbroughChampionship · England | 2–0 | Championship · England |
| 2010-08-28 | Werder BremenvFC KolnBundesliga · Germany | 4–2 | Bundesliga · Germany |
| 2010-08-28 | ArlesvRennesLigue 1 · France | 0–1 | Ligue 1 · France |
| 2010-08-28 | AlbinoleffevLivornoSerie B · Italy | 0–3 | Serie B · Italy |
| 2010-08-28 | MechelenvSt TruidenPro League · Belgium | 0–0 | Pro League · Belgium |
| 2010-08-28 | Port ValevTorquayLeague Two · England | 1–2 | League Two · England |
| 2010-08-28 | LorientvLyonLigue 1 · France | 2–0 | Ligue 1 · France |
| 2010-08-28 | CeltavBarcelona BLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2010-08-28 | StenhousemuirvAirdrie UtdLeague One · Scotland | 1–3 | League One · Scotland |
| 2010-08-28 | AberdeenvKilmarnockPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2010-08-28 | LivingstonvForfarLeague One · Scotland | 2–0 | League One · Scotland |
| 2010-08-28 | OxfordvAccringtonLeague Two · England | 0–0 | League Two · England |
| 2010-08-28 | LarisavAtromitosSuper League · Greece | 1–0 | Super League · Greece |
| 2010-08-28 | ScunthorpevCrystal PalaceChampionship · England | 3–0 | Championship · England |
| 2010-08-28 | Raith RvsvMortonChampionship · Scotland | 1–0 | Championship · Scotland |
| 2010-08-28 | MorecambevGillinghamLeague Two · England | 1–1 | League Two · England |
| 2010-08-28 | BuyuksehyrvKasimpasaSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |