| 2010-08-29 | MallorcavReal MadridLa Liga · Spain | 0–0 | La Liga · Spain |
| 2010-08-29 | MotherwellvCelticPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2010-08-29 | SalamancavCordobaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-08-29 | AlbacetevAlcorconLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-08-29 | OlhanensevLeiriaPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-08-29 | Den HaagvPSV EindhovenEredivisie · Netherlands | 2–2 | Eredivisie · Netherlands |
| 2010-08-29 | Beira MarvAcademicaPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2010-08-29 | AZ AlkmaarvExcelsiorEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2010-08-29 | GraafschapvAjaxEredivisie · Netherlands | 0–5 | Eredivisie · Netherlands |
| 2010-08-29 |  MonacovAuxerreLigue 1 · France | 2–0 | Ligue 1 · France |
| 2010-08-29 | Aston VillavEvertonPremier League · England | 1–0 | Premier League · England |
| 2010-08-29 | ErgotelisvAsteras TripolisSuper League · Greece | 0–1 | Super League · Greece |
| 2010-08-29 | Munich 1860vOsnabruck2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2010-08-28 | BrechinvAlloaLeague One · Scotland | 3–1 | League One · Scotland |
| 2010-08-28 | HartlepoolvSheffield WedsLeague One · England | 0–5 | League One · England |
| 2010-08-28 | SwanseavBurnleyChampionship · England | 1–0 | Championship · England |
| 2010-08-28 | OldhamvYeovilLeague One · England | 0–0 | League One · England |
| 2010-08-28 | BlackburnvArsenalPremier League · England | 1–2 | Premier League · England |
| 2010-08-28 | ValenciennesvMontpellierLigue 1 · France | 0–1 | Ligue 1 · France |
| 2010-08-28 | MontrosevAnnan AthleticLeague Two · Scotland | 1–1 | League Two · Scotland |
| 2010-08-28 | AldershotvStevenageLeague Two · England | 1–1 | League Two · England |
| 2010-08-28 | NancyvToulouseLigue 1 · France | 0–2 | Ligue 1 · France |
| 2010-08-28 | AyrvPeterheadLeague One · Scotland | 1–1 | League One · Scotland |
| 2010-08-28 | UdinesevGenoaSerie A · Italy | 0–1 | Serie A · Italy |
| 2010-08-28 | CaenvBrestLigue 1 · France | 0–2 | Ligue 1 · France |
| 2010-08-28 | BournemouthvNotts CountyLeague One · England | 3–3 | League One · England |
| 2010-08-28 | LincolnvCreweLeague Two · England | 1–1 | League Two · England |
| 2010-08-28 | PanioniosvOlympiakos VolouSuper League · Greece | 0–1 | Super League · Greece |
| 2010-08-28 | PortsmouthvCardiffChampionship · England | 0–2 | Championship · England |
| 2010-08-28 | TamworthvLutonNational League · England | 3–1 | National League · England |
| 2010-08-28 | BlackpoolvFulhamPremier League · England | 2–2 | Premier League · England |
| 2010-08-28 | DuisburgvIngolstadt2. Bundesliga · Germany | 4–1 | 2. Bundesliga · Germany |
| 2010-08-28 | St PaulivHoffenheimBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2010-08-28 | Ein FrankfurtvHamburgBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2010-08-28 | IpswichvBristol CityChampionship · England | 2–0 | Championship · England |
| 2010-08-28 | NurnbergvFreiburgBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2010-08-28 | East FifevDumbartonLeague One · Scotland | 6–0 | League One · Scotland |
| 2010-08-28 | CowdenbeathvPartickChampionship · Scotland | 2–1 | Championship · Scotland |
| 2010-08-28 | WrexhamvBarrowNational League · England | 1–1 | National League · England |
| 2010-08-28 | Sheffield UnitedvPrestonChampionship · England | 1–0 | Championship · England |
| 2010-08-28 | AnderlechtvWaregemPro League · Belgium | 0–0 | Pro League · Belgium |
| 2010-08-28 | Nott'm ForestvNorwichChampionship · England | 1–1 | Championship · England |
| 2010-08-28 | Bristol RvsvSouthamptonLeague One · England | 0–4 | League One · England |
| 2010-08-28 | PonferradinavHuescaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2010-08-28 | DundeevFalkirkChampionship · Scotland | 2–0 | Championship · Scotland |
| 2010-08-28 | Forest GreenvBath CityNational League · England | 0–0 | National League · England |
| 2010-08-28 | NorthamptonvWycombeLeague Two · England | 1–1 | League Two · England |
| 2010-08-28 | BarnetvBuryLeague Two · England | 1–1 | League Two · England |
| 2010-08-28 | PlymouthvPeterboroLeague One · England | 0–3 | League One · England |
| 2010-08-28 | ElginvStranraerLeague Two · Scotland | 1–2 | League Two · Scotland |