| 2016-10-02 | TorinovFiorentinaSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-10-02 | MalagavAth BilbaoLa Liga · Spain | 2–1 | La Liga · Spain |
| 2016-10-02 | HibernianvDundee UnitedChampionship · Scotland | 1–1 | Championship · Scotland |
| 2016-10-02 | KonyasporvAdanasporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2016-10-02 | Young BoysvSt. GallenSuper League · Switzerland | 2–2 | Super League · Switzerland |
| 2016-10-02 | KrasnodarvRubin KazanPremier League · Russia | 1–0 | Premier League · Russia |
| 2016-10-02 | GrasshoppersvLuzernSuper League · Switzerland | 3–2 | Super League · Switzerland |
| 2016-10-02 | NecaxavTolucaLiga MX · Mexico | 3–1 | Liga MX · Mexico |
| 2016-10-02 | LyonvSt EtienneLigue 1 · France | 2–0 | Ligue 1 · France |
| 2016-10-02 | LevantevValladolidLa Liga 2 · Spain | 3–2 | La Liga 2 · Spain |
| 2016-10-02 | KalmarvGoteborgAllsvenskan · Sweden | 4–2 | Allsvenskan · Sweden |
| 2016-10-02 | OsmanlisporvFenerbahceSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2016-10-02 | Willem IIvFeyenoordEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2016-10-02 | HeidenheimvBraunschweig2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-10-02 | AroucavSp BragaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-10-02 | VikingvStartEliteserien · Norway | 2–0 | Eliteserien · Norway |
| 2016-10-02 | AalborgvSonderjyskeSuperliga · Denmark | 0–1 | Superliga · Denmark |
| 2016-10-02 | San LorenzovAtl. RafaelaLiga Profesional · Argentina | 2–1 | Liga Profesional · Argentina |
| 2016-10-02 | BolognavGenoaSerie A · Italy | 0–1 | Serie A · Italy |
| 2016-10-02 | EmpolivJuventusSerie A · Italy | 0–3 | Serie A · Italy |
| 2016-10-02 | Man UnitedvStokePremier League · England | 1–1 | Premier League · England |
| 2016-10-02 | River PlatevVelez SarsfieldLiga Profesional · Argentina | 3–0 | Liga Profesional · Argentina |
| 2016-10-02 | Sarmiento JuninvIndependienteLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-10-02 | CracoviavKorona KielceEkstraklasa · Poland | 6–0 | Ekstraklasa · Poland |
| 2016-10-02 | Guadalajara ChivasvMonarcasLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2016-10-02 | Viitorul ConstantavAstraSuperliga · Romania | 1–0 | Superliga · Romania |
| 2016-10-02 | FK RostovvCSKA MoscowPremier League · Russia | 2–0 | Premier League · Russia |
| 2016-10-02 | UCAM MurciavMirandesLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2016-10-02 | TenerifevGetafeLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2016-10-02 | Columbus CrewvChicago FireMLS · United States | 3–0 | MLS · United States |
| 2016-10-02 | RomavInterSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-10-02 | FC DallasvLos Angeles GalaxyMLS · United States | 1–0 | MLS · United States |
| 2016-10-02 | StandardvAnderlechtPro League · Belgium | 0–1 | Pro League · Belgium |
| 2016-10-02 | Sparta RotterdamvAZ AlkmaarEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2016-10-02 | BanfieldvSan Martin S.J.Liga Profesional · Argentina | 3–2 | Liga Profesional · Argentina |
| 2016-10-02 | LyngbyvMidtjyllandSuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2016-10-02 | HeraclesvTwenteEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2016-10-02 | InternacionalvFigueirenseSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2016-10-02 | Club BruggevGentPro League · Belgium | 1–0 | Pro League · Belgium |
| 2016-10-02 | AIKvNorrkopingAllsvenskan · Sweden | 6–0 | Allsvenskan · Sweden |
| 2016-10-02 | BenficavFeirensePrimeira Liga · Portugal | 4–0 | Primeira Liga · Portugal |
| 2016-10-02 | ValenciavAth MadridLa Liga · Spain | 0–2 | La Liga · Spain |
| 2016-10-02 | Club LeonvTigres UANLLiga MX · Mexico | 3–2 | Liga MX · Mexico |
| 2016-10-02 | KaiserslauternvBielefeld2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2016-10-02 | GenkvMechelenPro League · Belgium | 2–1 | Pro League · Belgium |
| 2016-10-02 | Slask WroclawvTermalica B-B.Ekstraklasa · Poland | 1–2 | Ekstraklasa · Poland |
| 2016-10-02 | UNAM PumasvChiapasLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2016-10-02 | LausannevLuganoSuper League · Switzerland | 4–1 | Super League · Switzerland |
| 2016-10-02 | GeflevElfsborgAllsvenskan · Sweden | 2–2 | Allsvenskan · Sweden |
| 2016-10-02 | New York Red BullsvPhiladelphia UnionMLS · United States | 3–2 | MLS · United States |