| 2008-09-13 | LiverpoolvMan UnitedPremier League · England | 2–1 | Premier League · England |
| 2008-09-13 | Crawley TownvMansfieldNational League · England | 2–1 | National League · England |
| 2008-09-13 | CoventryvPrestonChampionship · England | 0–0 | Championship · England |
| 2008-09-13 | HuescavEibarLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2008-09-13 | Queens ParkvPeterheadLeague One · Scotland | 0–1 | League One · Scotland |
| 2008-09-13 | HerthavWolfsburgBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2008-09-13 | BlackburnvArsenalPremier League · England | 0–4 | Premier League · England |
| 2008-09-13 | HuddersfieldvTranmereLeague One · England | 1–2 | League One · England |
| 2008-09-13 | PortsmouthvMiddlesbroughPremier League · England | 2–1 | Premier League · England |
| 2008-09-13 | BordeauxvMarseilleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2008-09-13 | CowdenbeathvBerwickLeague Two · Scotland | 2–1 | League Two · Scotland |
| 2008-09-13 | MechelenvTubizePro League · Belgium | 0–0 | Pro League · Belgium |
| 2008-09-13 | HibernianvDundee UnitedPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2008-09-13 | Leyton OrientvStockportLeague One · England | 0–3 | League One · England |
| 2008-09-13 | HacettepesporvFenerbahceSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2008-09-13 | WiganvSunderlandPremier League · England | 1–1 | Premier League · England |
| 2008-09-13 | AlicantevCastellonLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2008-09-13 | YeovilvBrightonLeague One · England | 1–1 | League One · England |
| 2008-09-13 | CardiffvBristol CityChampionship · England | 0–0 | Championship · England |
| 2008-09-13 | BuryvLincolnLeague Two · England | 3–1 | League Two · England |
| 2008-09-13 | Club BruggevDenderPro League · Belgium | 1–1 | Pro League · Belgium |
| 2008-09-13 | GrimsbyvChesterLeague Two · England | 1–3 | League Two · England |
| 2008-09-13 | AccringtonvNotts CountyLeague Two · England | 1–1 | League Two · England |
| 2008-09-13 | Crystal PalacevSwanseaChampionship · England | 2–0 | Championship · England |
| 2008-09-13 | NorthamptonvPeterboroLeague One · England | 1–1 | League One · England |
| 2008-09-13 | NewcastlevHullPremier League · England | 1–2 | Premier League · England |
| 2008-09-13 | DortmundvSchalke 04Bundesliga · Germany | 3–3 | Bundesliga · Germany |
| 2008-09-13 | BrechinvArbroathLeague One · Scotland | 3–1 | League One · Scotland |
| 2008-09-13 | BlackpoolvBarnsleyChampionship · England | 1–0 | Championship · England |
| 2008-09-13 | East StirlingvStenhousemuirLeague Two · Scotland | 0–2 | League Two · Scotland |
| 2008-09-13 | CordobavSevilla BLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2008-09-13 | Ross CountyvSt JohnstoneChampionship · Scotland | 1–2 | Championship · Scotland |
| 2008-09-13 | LokerenvWesterloPro League · Belgium | 1–1 | Pro League · Belgium |
| 2008-09-13 | GalatasarayvAntalyasporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2008-09-13 | ValenciennesvGrenobleLigue 1 · France | 1–1 | Ligue 1 · France |
| 2008-09-13 | FC KolnvBayern MunichBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2008-09-13 | KayserisporvKocaelisporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2008-09-13 | FulhamvBoltonPremier League · England | 2–1 | Premier League · England |
| 2008-09-13 | Dag and RedvChesterfieldLeague Two · England | 3–0 | League Two · England |
| 2008-09-13 | WrexhamvEbbsfleetNational League · England | 3–2 | National League · England |
| 2008-09-13 | IntervCataniaSerie A · Italy | 2–1 | Serie A · Italy |
| 2008-09-13 | WycombevBrentfordLeague Two · England | 0–0 | League Two · England |
| 2008-09-13 | ParmavAnconaSerie B · Italy | 4–1 | Serie B · Italy |
| 2008-09-13 | RennesvLe HavreLigue 1 · France | 1–1 | Ligue 1 · France |
| 2008-09-13 | Raith RvsvEast FifeLeague One · Scotland | 1–1 | League One · Scotland |
| 2008-09-13 | ScunthorpevCarlisleLeague One · England | 2–1 | League One · England |
| 2008-09-13 | ValladolidvAth MadridLa Liga · Spain | 2–1 | La Liga · Spain |
| 2008-09-13 | KidderminstervOxfordNational League · England | 1–0 | National League · England |
| 2008-09-13 | PSV EindhovenvSpartaEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2008-09-13 | Sheffield WedsvWatfordChampionship · England | 2–0 | Championship · England |