| 2008-09-20 | RomavRegginaSerie A · Italy | 3–0 | Serie A · Italy |
| 2008-09-20 | KortrijkvBergenPro League · Belgium | 1–0 | Pro League · Belgium |
| 2008-09-20 | StenhousemuirvBerwickLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2008-09-20 | BrentfordvLincolnLeague Two · England | 1–1 | League Two · England |
| 2008-09-20 | Sheffield WedsvIpswichChampionship · England | 0–0 | Championship · England |
| 2008-09-20 | ExetervNotts CountyLeague Two · England | 2–2 | League Two · England |
| 2008-09-20 | GimnasticvAlicanteLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2008-09-20 | BarnetvBuryLeague Two · England | 1–2 | League Two · England |
| 2008-09-20 | Sp LisbonvBelenensesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2008-09-20 | ElginvAlbion RvsLeague Two · Scotland | 1–6 | League Two · Scotland |
| 2008-09-20 | PrestonvWolvesChampionship · England | 1–3 | Championship · England |
| 2008-09-20 | BirminghamvBlackpoolChampionship · England | 0–1 | Championship · England |
| 2008-09-20 | Sevilla BvVallecanoLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2008-09-20 | Cercle BruggevGerminalPro League · Belgium | 1–0 | Pro League · Belgium |
| 2008-09-20 | EspanolvGetafeLa Liga · Spain | 1–1 | La Liga · Spain |
| 2008-09-20 | EbbsfleetvWokingNational League · England | 2–0 | National League · England |
| 2008-09-20 | Leyton OrientvLeicesterLeague One · England | 1–3 | League One · England |
| 2008-09-20 | YeovilvBristol RvsLeague One · England | 2–2 | League One · England |
| 2008-09-20 | GentvMechelenPro League · Belgium | 1–2 | Pro League · Belgium |
| 2008-09-20 | MurciavLas PalmasLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2008-09-20 | LorientvCaenLigue 1 · France | 1–1 | Ligue 1 · France |
| 2008-09-20 | AberdeenvDundee UnitedPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2008-09-20 | LiverpoolvStokePremier League · England | 0–0 | Premier League · England |
| 2008-09-20 | DarlingtonvAccringtonLeague Two · England | 3–0 | League Two · England |
| 2008-09-20 | PeterheadvStranraerLeague One · Scotland | 4–0 | League One · Scotland |
| 2008-09-20 | CrewevSouthendLeague One · England | 3–4 | League One · England |
| 2008-09-20 | VitessevSpartaEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2008-09-20 | Bristol CityvDoncasterChampionship · England | 4–1 | Championship · England |
| 2008-09-20 | BresciavAscoliSerie B · Italy | 2–1 | Serie B · Italy |
| 2008-09-20 | HeraclesvGroningenEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2008-09-19 | MontpelliervSedanLigue 2 · France | 3–1 | Ligue 2 · France |
| 2008-09-19 | CittadellavMantovaSerie B · Italy | 0–2 | Serie B · Italy |
| 2008-09-19 | LeverkusenvHannoverBundesliga · Germany | 4–0 | Bundesliga · Germany |
| 2008-09-19 | AmiensvBrestLigue 2 · France | 2–1 | Ligue 2 · France |
| 2008-09-19 | ModenavSalernitanaSerie B · Italy | 0–1 | Serie B · Italy |
| 2008-09-19 | AhlenvHansa Rostock2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2008-09-19 | AngersvNimesLigue 2 · France | 2–2 | Ligue 2 · France |
| 2008-09-19 | DenizlisporvTrabzonsporSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2008-09-19 | StrasbourgvVannesLigue 2 · France | 2–1 | Ligue 2 · France |
| 2008-09-19 | UtrechtvWillem IIEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2008-09-19 | MetzvReimsLigue 2 · France | 0–0 | Ligue 2 · France |
| 2008-09-19 | ToursvChateaurouxLigue 2 · France | 3–1 | Ligue 2 · France |
| 2008-09-19 | BoulognevBastiaLigue 2 · France | 1–0 | Ligue 2 · France |
| 2008-09-19 | AjacciovClermontLigue 2 · France | 5–1 | Ligue 2 · France |
| 2008-09-19 |  Martiniquev AnguillaCFU Caribbean Cup qualification | 3–1 | CFU Caribbean Cup qualification |
| 2008-09-19 | GuingampvDijonLigue 2 · France | 1–1 | Ligue 2 · France |
| 2008-09-19 | AnderlechtvCharleroiPro League · Belgium | 2–0 | Pro League · Belgium |
| 2008-09-19 | MainzvNurnberg2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2008-09-19 | DuisburgvAachen2. Bundesliga · Germany | 3–2 | 2. Bundesliga · Germany |
| 2008-09-19 | St PaulivMunich 18602. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |