| 2000-09-16 | CharltonvTottenhamPremier League · England | 1–0 | Premier League · England |
| 2000-09-16 | PanathinaikosvYianninaSuper League · Greece | 2–1 | Super League · Greece |
| 2000-09-16 | Aston VillavBradfordPremier League · England | 2–0 | Premier League · England |
| 2000-09-16 | KidderminstervLeyton OrientLeague Two · England | 2–1 | League Two · England |
| 2000-09-16 | LeverkusenvHansa RostockBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2000-09-16 | RochdalevTorquayLeague Two · England | 2–1 | League Two · England |
| 2000-09-16 | PartickvStirlingLeague One · Scotland | 3–1 | League One · Scotland |
| 2000-09-16 | ValladolidvNumanciaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2000-09-16 | SantandervLa CorunaLa Liga · Spain | 0–3 | La Liga · Spain |
| 2000-09-15 | DuisburgvSt Pauli2. Bundesliga · Germany | 4–1 | 2. Bundesliga · Germany |
| 2000-09-15 | Sheffield UnitedvBlackburnChampionship · England | 2–0 | Championship · England |
| 2000-09-15 | KocaelisporvGalatasaraySüper Lig · Turkey | 1–4 | Süper Lig · Turkey |
| 2000-09-15 | KaiserslauternvFC KolnBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2000-09-15 | GuimaraesvGil VicentePrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2000-09-15 | NancyvMartiguesLigue 2 · France | 0–0 | Ligue 2 · France |
| 2000-09-15 | ChievovTrevisoSerie B · Italy | 2–1 | Serie B · Italy |
| 2000-09-15 | HannovervMannheim2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2000-09-13 | NAC BredavRoosendaalEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2000-09-13 | Sheffield WedsvNott'm ForestChampionship · England | 0–1 | Championship · England |
| 2000-09-13 | QPRvGillinghamChampionship · England | 2–2 | Championship · England |
| 2000-09-13 | StokevOxfordLeague One · England | 4–0 | League One · England |
| 2000-09-12 | CardiffvHalifaxLeague Two · England | 4–2 | League Two · England |
| 2000-09-12 | Leyton OrientvScunthorpeLeague Two · England | 1–1 | League Two · England |
| 2000-09-12 | BlackpoolvBrightonLeague Two · England | 0–2 | League Two · England |
| 2000-09-12 | GrimsbyvBoltonChampionship · England | 0–1 | Championship · England |
| 2000-09-12 | WolvesvSheffield UnitedChampionship · England | 0–0 | Championship · England |
| 2000-09-12 | BarnetvExeterLeague Two · England | 1–1 | League Two · England |
| 2000-09-12 | LutonvWalsallLeague One · England | 0–0 | League One · England |
| 2000-09-12 | MansfieldvHullLeague Two · England | 1–1 | League Two · England |
| 2000-09-12 | FulhamvBurnleyChampionship · England | 3–1 | Championship · England |
| 2000-09-12 | SouthendvKidderminsterLeague Two · England | 1–1 | League Two · England |
| 2000-09-12 | Notts CountyvSwanseaLeague One · England | 0–1 | League One · England |
| 2000-09-12 | BirminghamvPrestonChampionship · England | 3–1 | Championship · England |
| 2000-09-12 | PortsmouthvTranmereChampionship · England | 2–0 | Championship · England |
| 2000-09-12 | CheltenhamvDarlingtonLeague Two · England | 1–0 | League Two · England |
| 2000-09-12 | CarlislevChesterfieldLeague Two · England | 2–4 | League Two · England |
| 2000-09-12 | HuddersfieldvWimbledonChampionship · England | 0–2 | Championship · England |
| 2000-09-12 | WycombevBristol RvsLeague One · England | 0–1 | League One · England |
| 2000-09-12 | CambridgevPort ValeLeague One · England | 4–0 | League One · England |
| 2000-09-12 | BournemouthvSwindonLeague One · England | 3–0 | League One · England |
| 2000-09-12 | WrexhamvRotherhamLeague One · England | 1–3 | League One · England |
| 2000-09-12 | StockportvNorwichChampionship · England | 1–3 | Championship · England |
| 2000-09-12 | ShrewsburyvPlymouthLeague Two · England | 4–1 | League Two · England |
| 2000-09-12 | Crystal PalacevBarnsleyChampionship · England | 1–0 | Championship · England |
| 2000-09-12 | BlackburnvWatfordChampionship · England | 3–4 | Championship · England |
| 2000-09-12 | MillwallvNorthamptonLeague One · England | 0–1 | League One · England |
| 2000-09-12 | TorquayvHartlepoolLeague Two · England | 1–0 | League Two · England |
| 2000-09-12 | WiganvPeterboroLeague One · England | 1–0 | League One · England |
| 2000-09-12 | CrewevWest BromChampionship · England | 0–1 | Championship · England |
| 2000-09-12 | BuryvColchesterLeague One · England | 0–0 | League One · England |