| 2005-09-21 | WesterlovLiersePro League · Belgium | 0–0 | Pro League · Belgium |
| 2005-09-21 | VillarrealvCeltaLa Liga · Spain | 1–2 | La Liga · Spain |
| 2005-09-21 | BurghausenvCottbus2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2005-09-21 | TrevisovSampdoriaSerie A · Italy | 0–2 | Serie A · Italy |
| 2005-09-21 | SevillavCadizLa Liga · Spain | 0–0 | La Liga · Spain |
| 2005-09-21 | Paris SGvLilleLigue 1 · France | 2–1 | Ligue 1 · France |
| 2005-09-21 | AjaxvDen HaagEredivisie · Netherlands | 2–2 | Eredivisie · Netherlands |
| 2005-09-21 | LouvieroisevGenkPro League · Belgium | 2–3 | Pro League · Belgium |
| 2005-09-21 | AscolivSienaSerie A · Italy | 1–1 | Serie A · Italy |
| 2005-09-21 | MessinavLivornoSerie A · Italy | 0–0 | Serie A · Italy |
| 2005-09-21 | StandardvClub BruggePro League · Belgium | 2–0 | Pro League · Belgium |
| 2005-09-21 | ToulousevMarseilleLigue 1 · France | 1–0 | Ligue 1 · France |
| 2005-09-21 | MalagavAlavesLa Liga · Spain | 0–0 | La Liga · Spain |
| 2005-09-21 | Cercle BruggevGerminalPro League · Belgium | 3–0 | Pro League · Belgium |
| 2005-09-21 | RiminivVeronaSerie B · Italy | 0–0 | Serie B · Italy |
| 2005-09-21 | PalermovRegginaSerie A · Italy | 1–0 | Serie A · Italy |
| 2005-09-21 | UdinesevJuventusSerie A · Italy | 0–1 | Serie A · Italy |
| 2005-09-21 | PaderbornvGreuther Furth2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2005-09-21 | BarcelonavValenciaLa Liga · Spain | 2–2 | La Liga · Spain |
| 2005-09-21 | EmpolivCagliariSerie A · Italy | 3–1 | Serie A · Italy |
| 2005-09-21 | RennesvBordeauxLigue 1 · France | 2–2 | Ligue 1 · France |
| 2005-09-21 | StuttgartvHamburgBundesliga · Germany | 1–2 | Bundesliga · Germany |
| 2005-09-21 | GetafevMallorcaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2005-09-21 | KaiserslauternvMainzBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2005-09-21 | AachenvAhlen2. Bundesliga · Germany | 6–2 | 2. Bundesliga · Germany |
| 2005-09-21 | SantandervEspanolLa Liga · Spain | 1–0 | La Liga · Spain |
| 2005-09-21 | MilanvLazioSerie A · Italy | 2–0 | Serie A · Italy |
| 2005-09-21 | ChievovInterSerie A · Italy | 0–1 | Serie A · Italy |
| 2005-09-20 | GraysvCambridgeNational League · England | 5–3 | National League · England |
| 2005-09-20 | KarlsruhevUnterhaching2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2005-09-20 | AltrinchamvScarboroughNational League · England | 1–1 | National League · England |
| 2005-09-20 | BurtonvMorecambeNational League · England | 0–4 | National League · England |
| 2005-09-20 | CataniavAtalantaSerie B · Italy | 4–1 | Serie B · Italy |
| 2005-09-20 | BolognavPiacenzaSerie B · Italy | 2–1 | Serie B · Italy |
| 2005-09-20 | AlbinoleffevModenaSerie B · Italy | 0–0 | Serie B · Italy |
| 2005-09-20 | TernanavCesenaSerie B · Italy | 0–3 | Serie B · Italy |
| 2005-09-20 | AvellinovBariSerie B · Italy | 1–1 | Serie B · Italy |
| 2005-09-20 | StevenagevExeterNational League · England | 2–0 | National League · England |
| 2005-09-20 | YorkvDag and RedNational League · England | 1–1 | National League · England |
| 2005-09-20 | DortmundvBielefeldBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2005-09-20 | CatanzarovPescaraSerie B · Italy | 1–0 | Serie B · Italy |
| 2005-09-20 | M'gladbachvWerder BremenBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2005-09-20 | Ein FrankfurtvBayern MunichBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2005-09-20 | GentvFC BrusselsPro League · Belgium | 2–1 | Pro League · Belgium |
| 2005-09-20 | VicenzavMantovaSerie B · Italy | 0–1 | Serie B · Italy |
| 2005-09-20 | BraunschweigvOffenbach2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2005-09-20 | Nott'm ForestvBristol CityLeague One · England | 3–1 | League One · England |
| 2005-09-20 | WokingvCanvey IslandNational League · England | 1–1 | National League · England |
| 2005-09-20 | AccringtonvAldershotNational League · England | 3–2 | National League · England |
| 2005-09-20 | Forest GreenvCrawley TownNational League · England | 2–2 | National League · England |