| 2017-10-21 | St. PoltenvLASKBundesliga · Austria | 0–1 | Bundesliga · Austria |
| 2017-10-21 | Sligo RoversvDerry CityPremier Division · Ireland | 3–0 | Premier Division · Ireland |
| 2017-10-21 | MonarcasvClub LeonLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2017-10-21 | ExetervPort ValeLeague Two · England | 0–1 | League Two · England |
| 2017-10-21 | RennesvLilleLigue 1 · France | 1–0 | Ligue 1 · France |
| 2017-10-21 | CesenavFoggiaSerie B · Italy | 3–3 | Serie B · Italy |
| 2017-10-21 | SwanseavLeicesterPremier League · England | 1–2 | Premier League · England |
| 2017-10-21 | ShrewsburyvFleetwood TownLeague One · England | 1–0 | League One · England |
| 2017-10-21 | LevadeiakosvGianninaSuper League · Greece | 1–1 | Super League · Greece |
| 2017-10-21 | Lechia GdanskvLech PoznanEkstraklasa · Poland | 3–3 | Ekstraklasa · Poland |
| 2017-10-21 | St TruidenvOostendePro League · Belgium | 1–0 | Pro League · Belgium |
| 2017-10-21 | DunfermlinevLivingstonChampionship · Scotland | 3–1 | Championship · Scotland |
| 2017-10-21 | DoncastervWalsallLeague One · England | 0–3 | League One · England |
| 2017-10-21 | SetubalvMaritimoPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2017-10-21 | DerbyvSheffield WedsChampionship · England | 2–0 | Championship · England |
| 2017-10-21 | BoltonvQPRChampionship · England | 1–1 | Championship · England |
| 2017-10-21 | FeirensevRio AvePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2017-10-21 | AalesundvKristiansundEliteserien · Norway | 1–1 | Eliteserien · Norway |
| 2017-10-21 | Sturm GrazvMattersburgBundesliga · Austria | 3–2 | Bundesliga · Austria |
| 2017-10-21 | VeneziavEmpoliSerie B · Italy | 1–0 | Serie B · Italy |
| 2017-10-21 | Dag and RedvWrexhamNational League · England | 0–1 | National League · England |
| 2017-10-21 | ChestervBoreham WoodNational League · England | 1–2 | National League · England |
| 2017-10-21 | LensvReimsLigue 2 · France | 0–1 | Ligue 2 · France |
| 2017-10-21 | GillinghamvNorthamptonLeague One · England | 1–2 | League One · England |
| 2017-10-21 | MillwallvBirminghamChampionship · England | 2–0 | Championship · England |
| 2017-10-21 | PartickvDundeePremiership · Scotland | 2–1 | Premiership · Scotland |
| 2017-10-21 | LorcavTenerifeLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2017-10-21 | MorecambevGrimsbyLeague Two · England | 0–0 | League Two · England |
| 2017-10-21 | Sheffield UnitedvReadingChampionship · England | 2–1 | Championship · England |
| 2017-10-21 | SpeziavPerugiaSerie B · Italy | 4–2 | Serie B · Italy |
| 2017-10-21 | LevantevGetafeLa Liga · Spain | 1–1 | La Liga · Spain |
| 2017-10-21 | CambridgevChesterfieldLeague Two · England | 2–1 | League Two · England |
| 2017-10-21 | VascovCoritibaSerie A · Brazil | 1–1 | Serie A · Brazil |
| 2017-10-21 | Bristol CityvLeedsChampionship · England | 0–3 | Championship · England |
| 2017-10-21 | SKA KhabarovskvUfaPremier League · Russia | 2–2 | Premier League · Russia |
| 2017-10-21 | FalkirkvSt MirrenChampionship · Scotland | 0–0 | Championship · Scotland |
| 2017-10-21 | ClydevPeterheadLeague Two · Scotland | 1–4 | League Two · Scotland |
| 2017-10-21 | BrechinvQueen of SthChampionship · Scotland | 0–1 | Championship · Scotland |
| 2017-10-21 | Nott'm ForestvBurtonChampionship · England | 2–0 | Championship · England |
| 2017-10-21 | Vissel KobevSagan TosuJ1 League · Japan | 1–2 | J1 League · Japan |
| 2017-10-21 | BlackpoolvWiganLeague One · England | 1–3 | League One · England |
| 2017-10-21 | VVV VenlovDen HaagEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2017-10-21 | AtlasvClub TijuanaLiga MX · Mexico | 1–0 | Liga MX · Mexico |
| 2017-10-21 | BarcelonavMalagaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2017-10-21 | BetisvAlavesLa Liga · Spain | 2–0 | La Liga · Spain |
| 2017-10-21 | ZurichvGrasshoppersSuper League · Switzerland | 0–4 | Super League · Switzerland |
| 2017-10-21 | M'gladbachvLeverkusenBundesliga · Germany | 1–5 | Bundesliga · Germany |
| 2017-10-21 | Sevilla BvZaragozaLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2017-10-21 | CarlislevNotts CountyLeague Two · England | 1–1 | League Two · England |
| 2017-10-21 | CrewevAccringtonLeague Two · England | 0–2 | League Two · England |