| 2017-10-21 | IwatavAlbirex NiigataJ1 League · Japan | 2–2 | J1 League · Japan |
| 2017-10-21 | ValenciavSevillaLa Liga · Spain | 4–0 | La Liga · Spain |
| 2017-10-21 | EupenvMechelenPro League · Belgium | 4–1 | Pro League · Belgium |
| 2017-10-21 | Vegalta SendaivShimizu S-PulseJ1 League · Japan | 0–0 | J1 League · Japan |
| 2017-10-21 | CoventryvColchesterLeague Two · England | 0–0 | League Two · England |
| 2017-10-21 | Pogon SzczecinvTermalica B-B.Ekstraklasa · Poland | 2–3 | Ekstraklasa · Poland |
| 2017-10-21 | HuescavCadizLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2017-10-21 | Yeni MalatyasporvTrabzonsporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2017-10-21 | QueretarovSantos LagunaLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2017-10-21 | PescaravAvellinoSerie B · Italy | 2–1 | Serie B · Italy |
| 2017-10-21 | ScunthorpevPeterboroLeague One · England | 2–1 | League One · England |
| 2017-10-21 | MetzvDijonLigue 1 · France | 1–2 | Ligue 1 · France |
| 2017-10-21 | HalifaxvTorquayNational League · England | 1–1 | National League · England |
| 2017-10-21 | BlackburnvPortsmouthLeague One · England | 3–0 | League One · England |
| 2017-10-21 | EbbsfleetvBarrowNational League · England | 3–2 | National League · England |
| 2017-10-21 | ArbroathvAirdrie UtdLeague One · Scotland | 7–1 | League One · Scotland |
| 2017-10-21 | KortrijkvGentPro League · Belgium | 1–1 | Pro League · Belgium |
| 2017-10-21 | AngersvToulouseLigue 1 · France | 0–1 | Ligue 1 · France |
| 2017-10-21 | CheltenhamvLincolnLeague Two · England | 1–0 | League Two · England |
| 2017-10-21 | CowdenbeathvStirlingLeague Two · Scotland | 0–3 | League Two · Scotland |
| 2017-10-21 | Rubin KazanvDynamo MoscowPremier League · Russia | 0–0 | Premier League · Russia |
| 2017-10-21 | LokerenvCharleroiPro League · Belgium | 1–1 | Pro League · Belgium |
| 2017-10-21 | Yokohama F. MarinosvKashima AntlersJ1 League · Japan | 3–2 | J1 League · Japan |
| 2017-10-21 | Viitorul ConstantavCFR ClujSuperliga · Romania | 1–0 | Superliga · Romania |
| 2017-10-21 | NewcastlevCrystal PalacePremier League · England | 1–0 | Premier League · England |
| 2017-10-21 | YanbianvHenan Songshan LongmenSuper League · China | 1–2 | Super League · China |
| 2017-10-21 | Ross CountyvHamiltonPremiership · Scotland | 2–1 | Premiership · Scotland |
| 2017-10-21 | NantesvGuingampLigue 1 · France | 2–1 | Ligue 1 · France |
| 2017-10-21 | ExcelsiorvSparta RotterdamEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2017-10-21 | Dundee UnitedvInverness CChampionship · Scotland | 0–2 | Championship · Scotland |
| 2017-10-21 | BarnsleyvHullChampionship · England | 0–1 | Championship · England |
| 2017-10-21 | BaselvThunSuper League · Switzerland | 2–1 | Super League · Switzerland |
| 2017-10-21 | MiddlesbroughvCardiffChampionship · England | 0–1 | Championship · England |
| 2017-10-21 | TwentevRodaEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2017-10-21 | ChelseavWatfordPremier League · England | 4–2 | Premier League · England |
| 2017-10-21 | Dover AthleticvMaidenheadNational League · England | 1–1 | National League · England |
| 2017-10-21 | AmiensvBordeauxLigue 1 · France | 1–0 | Ligue 1 · France |
| 2017-10-21 | BradfordvCharltonLeague One · England | 0–1 | League One · England |
| 2017-10-21 | TernanavAscoliSerie B · Italy | 1–1 | Serie B · Italy |
| 2017-10-21 |  MonacovCaenLigue 1 · France | 2–0 | Ligue 1 · France |
| 2017-10-21 | Leyton OrientvMacclesfieldNational League · England | 0–1 | National League · England |
| 2017-10-21 | AltachvWolfsberger ACBundesliga · Austria | 3–2 | Bundesliga · Austria |
| 2017-10-21 | SalernitanavFrosinoneSerie B · Italy | 1–1 | Serie B · Italy |
| 2017-10-21 | Spartak MoscowvAmkarPremier League · Russia | 0–0 | Premier League · Russia |
| 2017-10-21 | Holstein KielvBielefeld2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2017-10-21 | Aston VillavFulhamChampionship · England | 2–1 | Championship · England |
| 2017-10-21 | Union BerlinvGreuther Furth2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2017-10-21 | Cerezo OsakavKofuJ1 League · Japan | 2–0 | J1 League · Japan |
| 2017-10-21 | AFC EskilstunavElfsborgAllsvenskan · Sweden | 2–3 | Allsvenskan · Sweden |
| 2017-10-21 | Sanfrecce HiroshimavKawasaki FrontaleJ1 League · Japan | 0–3 | J1 League · Japan |