| 2005-09-24 | CoventryvHullChampionship · England | 0–2 | Championship · England |
| 2005-09-24 | BetisvBarcelonaLa Liga · Spain | 1–4 | La Liga · Spain |
| 2005-09-24 | Schalke 04vHannoverBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2005-09-24 | NorthamptonvCheltenhamLeague Two · England | 1–2 | League Two · England |
| 2005-09-24 | ZaragozavLa CorunaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2005-09-24 | BeverenvCharleroiPro League · Belgium | 1–1 | Pro League · Belgium |
| 2005-09-24 | ChesterfieldvHartlepoolLeague One · England | 3–1 | League One · England |
| 2005-09-24 | GenclerbirligivMalatyasporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |
| 2005-09-24 | Canvey IslandvSouthportNational League · England | 2–1 | National League · England |
| 2005-09-24 | PeterborovShrewsburyLeague Two · England | 0–2 | League Two · England |
| 2005-09-24 | NewcastlevMan CityPremier League · England | 1–0 | Premier League · England |
| 2005-09-24 | BirminghamvLiverpoolPremier League · England | 2–2 | Premier League · England |
| 2005-09-24 | Sheffield UnitedvDerbyChampionship · England | 2–1 | Championship · England |
| 2005-09-24 | MillwallvCardiffChampionship · England | 0–0 | Championship · England |
| 2005-09-24 | HerculesvNumanciaLa Liga 2 · Spain | 4–0 | La Liga 2 · Spain |
| 2005-09-24 | OlympiakosvAkratitosSuper League · Greece | 2–0 | Super League · Greece |
| 2005-09-24 | DumbartonvStirlingLeague One · Scotland | 2–0 | League One · Scotland |
| 2005-09-24 | StokevWolvesChampionship · England | 1–3 | Championship · England |
| 2005-09-24 | West BromvCharltonPremier League · England | 1–2 | Premier League · England |
| 2005-09-24 | Club BruggevLokerenPro League · Belgium | 0–1 | Pro League · Belgium |
| 2005-09-24 | DenizlisporvGaziantepsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2005-09-24 | BielefeldvM'gladbachBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2005-09-24 | MantovavRiminiSerie B · Italy | 3–1 | Serie B · Italy |
| 2005-09-24 | TamworthvWokingNational League · England | 0–1 | National League · England |
| 2005-09-24 | LleidavXerezLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2005-09-24 | PanathinaikosvPanioniosSuper League · Greece | 3–0 | Super League · Greece |
| 2005-09-24 | KilmarnockvFalkirkPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2005-09-24 | West HamvArsenalPremier League · England | 0–0 | Premier League · England |
| 2005-09-24 | Albion RvsvBerwickLeague Two · Scotland | 0–2 | League Two · Scotland |
| 2005-09-24 | GravesendvKidderminsterNational League · England | 1–2 | National League · England |
| 2005-09-24 | StockportvChesterLeague Two · England | 0–0 | League Two · England |
| 2005-09-24 | GenkvCercle BruggePro League · Belgium | 3–1 | Pro League · Belgium |
| 2005-09-24 | RotherhamvSouthendLeague One · England | 2–4 | League One · England |
| 2005-09-24 | PSV EindhovenvRoosendaalEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2005-09-24 | ColchestervHuddersfieldLeague One · England | 1–1 | League One · England |
| 2005-09-24 | HeartsvRangersPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2005-09-24 | BurnleyvBrightonChampionship · England | 1–1 | Championship · England |
| 2005-09-24 | OldhamvBournemouthLeague One · England | 1–0 | League One · England |
| 2005-09-24 | CrotonevCataniaSerie B · Italy | 3–1 | Serie B · Italy |
| 2005-09-24 | BordeauxvAjaccioLigue 1 · France | 1–0 | Ligue 1 · France |
| 2005-09-24 |  MonacovNiceLigue 1 · France | 0–0 | Ligue 1 · France |
| 2005-09-24 | ExetervBurtonNational League · England | 1–2 | National League · England |
| 2005-09-24 | Man UnitedvBlackburnPremier League · England | 1–2 | Premier League · England |
| 2005-09-24 | LillevSt EtienneLigue 1 · France | 2–0 | Ligue 1 · France |
| 2005-09-24 | PortovBelenensesPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2005-09-24 | WolfsburgvEin FrankfurtBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2005-09-24 | BrechinvStranraerChampionship · Scotland | 2–3 | Championship · Scotland |
| 2005-09-24 | OxfordvBuryLeague Two · England | 2–1 | League Two · England |
| 2005-09-24 | EspanolvVillarrealLa Liga · Spain | 1–2 | La Liga · Spain |
| 2005-09-24 | PartickvForfarLeague One · Scotland | 1–0 | League One · Scotland |