| 2016-10-22 | Chongqing Liangjiang AthleticvJiangsu SuningSuper League · China | 2–2 | Super League · China |
| 2016-10-22 | StenhousemuirvBrechinLeague One · Scotland | 1–3 | League One · Scotland |
| 2016-10-22 | Sp LisbonvTondelaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-10-22 | SampdoriavGenoaSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-10-22 | MechelenvMouscronPro League · Belgium | 2–0 | Pro League · Belgium |
| 2016-10-22 | LuganovBaselSuper League · Switzerland | 2–2 | Super League · Switzerland |
| 2016-10-22 | QuilmesvLanusLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-10-22 | HuddersfieldvDerbyChampionship · England | 1–0 | Championship · England |
| 2016-10-22 | YorkvChesterNational League · England | 1–1 | National League · England |
| 2016-10-22 | GillinghamvCharltonLeague One · England | 1–1 | League One · England |
| 2016-10-22 | PSV EindhovenvSparta RotterdamEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2016-10-21 | TroyesvBourg PeronnasLigue 2 · France | 1–0 | Ligue 2 · France |
| 2016-10-21 | GalwayvLongfordPremier Division · Ireland | 0–0 | Premier Division · Ireland |
| 2016-10-21 | GaziantepsporvKayserisporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2016-10-21 | RizesporvGenclerbirligiSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2016-10-21 | Viitorul ConstantavCFR ClujSuperliga · Romania | 2–1 | Superliga · Romania |
| 2016-10-21 |  Laosv BruneiAFF Championship qualification | 4–3 | AFF Championship qualification |
| 2016-10-21 | BurtonvBirminghamChampionship · England | 2–0 | Championship · England |
| 2016-10-21 |  Cambodiav Timor-LesteAFF Championship qualification | 3–2 | AFF Championship qualification |
| 2016-10-21 | Krylya SovetovvArsenal TulaPremier League · Russia | 1–1 | Premier League · Russia |
| 2016-10-21 | OsasunavBetisLa Liga · Spain | 1–2 | La Liga · Spain |
| 2016-10-21 | Ajaccio GFCOvOrleansLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-10-21 | Fortuna DusseldorfvBielefeld2. Bundesliga · Germany | 4–0 | 2. Bundesliga · Germany |
| 2016-10-21 | Sarmiento JuninvOlimpo Bahia BlancaLiga Profesional · Argentina | 1–1 | Liga Profesional · Argentina |
| 2016-10-21 | Derry CityvSligo RoversPremier Division · Ireland | 2–1 | Premier Division · Ireland |
| 2016-10-21 | VikingvAalesundEliteserien · Norway | 2–3 | Eliteserien · Norway |
| 2016-10-21 |  MonacovMontpellierLigue 1 · France | 6–2 | Ligue 1 · France |
| 2016-10-21 | ViborgvSilkeborgSuperliga · Denmark | 1–3 | Superliga · Denmark |
| 2016-10-21 | OostendevKortrijkPro League · Belgium | 2–2 | Pro League · Belgium |
| 2016-10-21 | Pacos FerreiravNacionalPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-10-21 | ConcordiavPoli TimisoaraSuperliga · Romania | 0–2 | Superliga · Romania |
| 2016-10-21 | NimesvSochauxLigue 2 · France | 0–0 | Ligue 2 · France |
| 2016-10-21 | Wurzburger KickersvKarlsruhe2. Bundesliga · Germany | 0–2 | 2. Bundesliga · Germany |
| 2016-10-21 | StrasbourgvAuxerreLigue 2 · France | 2–1 | Ligue 2 · France |
| 2016-10-21 | StuttgartvMunich 18602. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2016-10-21 | ExcelsiorvZwolleEredivisie · Netherlands | 0–2 | Eredivisie · Netherlands |
| 2016-10-21 | Arka GdyniavPogon SzczecinEkstraklasa · Poland | 0–3 | Ekstraklasa · Poland |
| 2016-10-21 | WislavTermalica B-B.Ekstraklasa · Poland | 2–0 | Ekstraklasa · Poland |
| 2016-10-21 | SpeziavBresciaSerie B · Italy | 2–0 | Serie B · Italy |
| 2016-10-21 | WexfordvFinn HarpsPremier Division · Ireland | 0–0 | Premier Division · Ireland |
| 2016-10-21 | AalborgvNordsjaellandSuperliga · Denmark | 1–1 | Superliga · Denmark |
| 2016-10-21 | Cork CityvSt. PatricksPremier Division · Ireland | 3–1 | Premier Division · Ireland |
| 2016-10-21 | ToursvValenciennesLigue 2 · France | 4–1 | Ligue 2 · France |
| 2016-10-21 | HamburgvEin FrankfurtBundesliga · Germany | 0–3 | Bundesliga · Germany |
| 2016-10-21 | GeflevSundsvallAllsvenskan · Sweden | 1–1 | Allsvenskan · Sweden |
| 2016-10-21 | MaritimovBoavistaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2016-10-21 | Le HavrevAjaccioLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-10-21 | LavalvBrestLigue 2 · France | 0–1 | Ligue 2 · France |
| 2016-10-21 | CittadellavAscoliSerie B · Italy | 0–1 | Serie B · Italy |
| 2016-10-21 | Shamrock RoversvBrayPremier Division · Ireland | 0–0 | Premier Division · Ireland |