| 2008-10-04 | Queens ParkvStirlingLeague One · Scotland | 1–1 | League One · Scotland |
| 2008-10-04 | BresciavFrosinoneSerie B · Italy | 2–1 | Serie B · Italy |
| 2008-10-04 | GironavVallecanoLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2008-10-04 | ClydevDunfermlineChampionship · Scotland | 0–2 | Championship · Scotland |
| 2008-10-04 | HeartsvKilmarnockPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2008-10-04 | HerefordvWalsallLeague One · England | 0–0 | League One · England |
| 2008-10-04 | AntalyasporvGaziantepsporSüper Lig · Turkey | 1–4 | Süper Lig · Turkey |
| 2008-10-04 | WesterlovWaregemPro League · Belgium | 3–2 | Pro League · Belgium |
| 2008-10-04 | MillwallvMilton Keynes DonsLeague One · England | 0–4 | League One · England |
| 2008-10-04 | BirminghamvQPRChampionship · England | 1–0 | Championship · England |
| 2008-10-04 | DumbartonvAnnan AthleticLeague Two · Scotland | 4–1 | League Two · Scotland |
| 2008-10-04 | Bayern MunichvBochumBundesliga · Germany | 3–3 | Bundesliga · Germany |
| 2008-10-04 | GraysvLewesNational League · England | 0–0 | National League · England |
| 2008-10-04 |  Martiniquev RéunionCoupe de l'Outre-Mer | 0–1 | Coupe de l'Outre-Mer |
| 2008-10-04 | GenkvMechelenPro League · Belgium | 2–1 | Pro League · Belgium |
| 2008-10-04 | NorwichvDerbyChampionship · England | 1–2 | Championship · England |
| 2008-10-04 | GrossetovAlbinoleffeSerie B · Italy | 2–2 | Serie B · Italy |
| 2008-10-04 | KidderminstervBarrowNational League · England | 0–1 | National League · England |
| 2008-10-04 | MansfieldvWokingNational League · England | 0–1 | National League · England |
| 2008-10-04 | YeovilvSouthendLeague One · England | 1–2 | League One · England |
| 2008-10-04 | Kettering TownvNorthwichNational League · England | 2–1 | National League · England |
| 2008-10-04 | ArbroathvRaith RvsLeague One · Scotland | 0–2 | League One · Scotland |
| 2008-10-04 | CowdenbeathvEast StirlingLeague Two · Scotland | 0–0 | League Two · Scotland |
| 2008-10-04 | LarisavOFISuper League · Greece | 4–3 | Super League · Greece |
| 2008-10-04 | PiacenzavSalernitanaSerie B · Italy | 0–1 | Serie B · Italy |
| 2008-10-04 | GentvLokerenPro League · Belgium | 1–1 | Pro League · Belgium |
| 2008-10-04 | HuddersfieldvLeicesterLeague One · England | 2–3 | League One · England |
| 2008-10-04 | XerezvLevanteLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2008-10-04 | ExetervGillinghamLeague Two · England | 3–0 | League Two · England |
| 2008-10-04 | SwanseavWolvesChampionship · England | 3–1 | Championship · England |
| 2008-10-04 | ToulousevAuxerreLigue 1 · France | 1–0 | Ligue 1 · France |
| 2008-10-04 | SassuolovTrevisoSerie B · Italy | 2–0 | Serie B · Italy |
| 2008-10-04 | East FifevStranraerLeague One · Scotland | 1–2 | League One · Scotland |
| 2008-10-04 | BlackburnvMan UnitedPremier League · England | 0–2 | Premier League · England |
| 2008-10-04 | DarlingtonvShrewsburyLeague Two · England | 1–1 | League Two · England |
| 2008-10-04 | WycombevBournemouthLeague Two · England | 3–1 | League Two · England |
| 2008-10-04 | HerculesvZaragozaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2008-10-04 | BarnsleyvDoncasterChampionship · England | 4–1 | Championship · England |
| 2008-10-04 | PisavTriestinaSerie B · Italy | 3–1 | Serie B · Italy |
| 2008-10-04 | Albion RvsvMontroseLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2008-10-04 | HeraclesvRoda JCEredivisie · Netherlands | 2–0 | Eredivisie · Netherlands |
| 2008-10-04 | StuttgartvWerder BremenBundesliga · Germany | 4–1 | Bundesliga · Germany |
| 2008-10-04 | BrightonvCheltenhamLeague One · England | 3–3 | League One · England |
| 2008-10-04 | GrenoblevNantesLigue 1 · France | 0–1 | Ligue 1 · France |
| 2008-10-04 | ReadingvBurnleyChampionship · England | 3–1 | Championship · England |
| 2008-10-04 | AltrinchamvEbbsfleetNational League · England | 2–0 | National League · England |
| 2008-10-04 | LillevValenciennesLigue 1 · France | 1–0 | Ligue 1 · France |
| 2008-10-04 | SunderlandvArsenalPremier League · England | 1–1 | Premier League · England |
| 2008-10-04 | Port ValevNotts CountyLeague Two · England | 1–2 | League Two · England |
| 2008-10-04 | EibarvAlbaceteLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |