| 2008-10-18 | HistonvCrawley TownNational League · England | 1–0 | National League · England |
| 2008-10-18 | DerbyvPlymouthChampionship · England | 2–1 | Championship · England |
| 2008-10-18 | East StirlingvBerwickLeague Two · Scotland | 1–0 | League Two · Scotland |
| 2008-10-18 | MechelenvWesterloPro League · Belgium | 1–3 | Pro League · Belgium |
| 2008-10-18 | EbbsfleetvTorquayNational League · England | 0–2 | National League · England |
| 2008-10-18 | GraysvWokingNational League · England | 1–1 | National League · England |
| 2008-10-18 | SochauxvLe HavreLigue 1 · France | 1–1 | Ligue 1 · France |
| 2008-10-18 | AlbinoleffevVicenzaSerie B · Italy | 0–4 | Serie B · Italy |
| 2008-10-18 | StevenagevSalisburyNational League · England | 2–0 | National League · England |
| 2008-10-18 | CardiffvCharltonChampionship · England | 2–0 | Championship · England |
| 2008-10-18 | FC KolnvCottbusBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2008-10-18 | BarrowvEastbourne BoroughNational League · England | 3–1 | National League · England |
| 2008-10-18 | BuyuksehyrvAntalyasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2008-10-18 | MorecambevRochdaleLeague Two · England | 1–1 | League Two · England |
| 2008-10-18 | ParmavEmpoliSerie B · Italy | 1–0 | Serie B · Italy |
| 2008-10-18 | CastellonvLevanteLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2008-10-18 | Ein FrankfurtvLeverkusenBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2008-10-18 | WeymouthvAltrinchamNational League · England | 2–0 | National League · England |
| 2008-10-18 | ExetervGrimsbyLeague Two · England | 0–0 | League Two · England |
| 2008-10-18 | BurnleyvBirminghamChampionship · England | 1–1 | Championship · England |
| 2008-10-18 | DendervGenkPro League · Belgium | 2–4 | Pro League · Belgium |
| 2008-10-18 | KilmarnockvMotherwellPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2008-10-18 | LokerenvKortrijkPro League · Belgium | 2–0 | Pro League · Belgium |
| 2008-10-18 | FalkirkvAberdeenPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2008-10-18 | KocaelisporvFenerbahceSüper Lig · Turkey | 2–3 | Süper Lig · Turkey |
| 2008-10-18 | NantesvSt EtienneLigue 1 · France | 1–0 | Ligue 1 · France |
| 2008-10-18 | ElginvStenhousemuirLeague Two · Scotland | 4–2 | League Two · Scotland |
| 2008-10-18 | FulhamvSunderlandPremier League · England | 0–0 | Premier League · England |
| 2008-10-18 | StockportvColchesterLeague One · England | 1–2 | League One · England |
| 2008-10-18 | CittadellavLivornoSerie B · Italy | 0–0 | Serie B · Italy |
| 2008-10-18 | MansfieldvWrexhamNational League · England | 1–2 | National League · England |
| 2008-10-18 | AldershotvBrentfordLeague Two · England | 1–1 | League Two · England |
| 2008-10-18 | MouscronvRoeselarePro League · Belgium | 2–0 | Pro League · Belgium |
| 2008-10-18 | QPRvNott'm ForestChampionship · England | 2–1 | Championship · England |
| 2008-10-18 | HacettepesporvDenizlisporSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2008-10-18 | WycombevDarlingtonLeague Two · England | 1–1 | League Two · England |
| 2008-10-18 | PanserraikosvAsteras TripolisSuper League · Greece | 0–0 | Super League · Greece |
| 2008-10-18 | Bristol CityvNorwichChampionship · England | 1–0 | Championship · England |
| 2008-10-18 | LewesvNorthwichNational League · England | 2–3 | National League · England |
| 2008-10-18 | Annan AthleticvCowdenbeathLeague Two · Scotland | 0–1 | League Two · Scotland |
| 2008-10-18 | KarlsruhevBayern MunichBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2008-10-18 | OldhamvLeicesterLeague One · England | 1–1 | League One · England |
| 2008-10-18 | NapolivJuventusSerie A · Italy | 2–1 | Serie A · Italy |
| 2008-10-18 | Paris SGvLorientLigue 1 · France | 3–2 | Ligue 1 · France |
| 2008-10-18 | BoltonvBlackburnPremier League · England | 0–0 | Premier League · England |
| 2008-10-18 | TenerifevSalamancaLa Liga 2 · Spain | 2–3 | La Liga 2 · Spain |
| 2008-10-18 |  Bangladeshv MyanmarMerdeka Tournament | 0–1 | Merdeka Tournament |
| 2008-10-18 | AjaxvGroningenEredivisie · Netherlands | 1–0 | Eredivisie · Netherlands |
| 2008-10-18 | NAC BredavPSV EindhovenEredivisie · Netherlands | 2–1 | Eredivisie · Netherlands |
| 2008-10-18 | GironavSociedadLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |