| 2008-10-26 | AlbacetevCeltaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2008-10-26 | MurciavSevilla BLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2008-10-26 | LaziovNapoliSerie A · Italy | 0–1 | Serie A · Italy |
| 2008-10-26 | HerculesvAlavesLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2008-10-26 | AnkaragucuvKayserisporSüper Lig · Turkey | 1–3 | Süper Lig · Turkey |
| 2008-10-26 | Pacos FerreiravSp LisbonPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2008-10-26 | MainzvDuisburg2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2008-10-26 | MallorcavEspanolLa Liga · Spain | 3–0 | La Liga · Spain |
| 2008-10-25 | HeartsvAberdeenPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2008-10-25 | CottbusvEin FrankfurtBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2008-10-25 | Willem IIvGraafschapEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2008-10-25 | MortonvDundeeChampionship · Scotland | 2–0 | Championship · Scotland |
| 2008-10-25 | ColchestervCarlisleLeague One · England | 5–0 | League One · England |
| 2008-10-25 | Le HavrevValenciennesLigue 1 · France | 2–1 | Ligue 1 · France |
| 2008-10-25 | NicevBordeauxLigue 1 · France | 2–2 | Ligue 1 · France |
| 2008-10-25 | BarcelonavAlmeriaLa Liga · Spain | 5–0 | La Liga · Spain |
| 2008-10-25 | WatfordvWolvesChampionship · England | 2–3 | Championship · England |
| 2008-10-25 | VicenzavSassuoloSerie B · Italy | 1–0 | Serie B · Italy |
| 2008-10-25 | M'gladbachvKarlsruheBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2008-10-25 | Inverness CvMotherwellPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2008-10-25 | Toulousev MonacoLigue 1 · France | 0–0 | Ligue 1 · France |
| 2008-10-25 | LorientvNantesLigue 1 · France | 3–0 | Ligue 1 · France |
| 2008-10-25 | AscolivCittadellaSerie B · Italy | 1–2 | Serie B · Italy |
| 2008-10-25 | BarnetvExeterLeague Two · England | 0–1 | League Two · England |
| 2008-10-25 | DenizlisporvGenclerbirligiSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2008-10-25 | AnkarasporvKocaelisporSüper Lig · Turkey | 4–0 | Süper Lig · Turkey |
| 2008-10-25 | BrentfordvShrewsburyLeague Two · England | 1–1 | League Two · England |
| 2008-10-25 | KilmarnockvFalkirkPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2008-10-25 | AvellinovFrosinoneSerie B · Italy | 0–0 | Serie B · Italy |
| 2008-10-25 | BirminghamvSheffield WedsChampionship · England | 3–1 | Championship · England |
| 2008-10-25 | PortovLeixoesPrimeira Liga · Portugal | 2–3 | Primeira Liga · Portugal |
| 2008-10-25 | JuventusvTorinoSerie A · Italy | 1–0 | Serie A · Italy |
| 2008-10-25 | AccringtonvWycombeLeague Two · England | 0–1 | League Two · England |
| 2008-10-25 | SwindonvOldhamLeague One · England | 2–0 | League One · England |
| 2008-10-25 | CordobavTenerifeLa Liga 2 · Spain | 2–0 | La Liga 2 · Spain |
| 2008-10-25 | AZ AlkmaarvVolendamEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2008-10-25 | ClydevLivingstonChampionship · Scotland | 2–1 | Championship · Scotland |
| 2008-10-25 | RennesvLe MansLigue 1 · France | 2–2 | Ligue 1 · France |
| 2008-10-25 | Port ValevMorecambeLeague Two · England | 2–1 | League Two · England |
| 2008-10-25 | PeterborovHuddersfieldLeague One · England | 4–0 | League One · England |
| 2008-10-25 | ZaragozavXerezLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2008-10-25 | ScunthorpevMillwallLeague One · England | 3–2 | League One · England |
| 2008-10-25 | Milton Keynes DonsvCheltenhamLeague One · England | 3–1 | League One · England |
| 2008-10-25 | HamiltonvRangersPremiership · Scotland | 1–3 | Premiership · Scotland |
| 2008-10-25 | AyrvStirlingLeague One · Scotland | 1–1 | League One · Scotland |
| 2008-10-25 | StranraervRaith RvsLeague One · Scotland | 0–2 | League One · Scotland |
| 2008-10-25 | Schalke 04vBielefeldBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2008-10-25 | HartlepoolvBrightonLeague One · England | 1–0 | League One · England |
| 2008-10-25 | GillinghamvChesterLeague Two · England | 2–0 | League Two · England |
| 2008-10-25 | Bayern MunichvWolfsburgBundesliga · Germany | 4–2 | Bundesliga · Germany |