| 2022-08-21 | EmpolivFiorentinaSerie A · Italy | 0–0 | Serie A · Italy |
| 2022-08-14 | FiorentinavCremoneseSerie A · Italy | 3–2 | Serie A · Italy |
| 2022-05-21 | FiorentinavJuventusSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-05-16 | SampdoriavFiorentinaSerie A · Italy | 4–1 | Serie A · Italy |
| 2022-05-09 | FiorentinavRomaSerie A · Italy | 2–0 | Serie A · Italy |
| 2022-05-01 | MilanvFiorentinaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-04-27 | FiorentinavUdineseSerie A · Italy | 0–4 | Serie A · Italy |
| 2022-04-24 | SalernitanavFiorentinaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-04-16 | FiorentinavVeneziaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-04-10 | NapolivFiorentinaSerie A · Italy | 2–3 | Serie A · Italy |
| 2022-04-03 | FiorentinavEmpoliSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-03-19 | IntervFiorentinaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-03-13 | FiorentinavBolognaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-03-06 | FiorentinavVeronaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-02-26 | SassuolovFiorentinaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-02-20 | FiorentinavAtalantaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-02-14 | SpeziavFiorentinaSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-02-05 | FiorentinavLazioSerie A · Italy | 0–3 | Serie A · Italy |
| 2022-01-23 | CagliarivFiorentinaSerie A · Italy | 1–1 | Serie A · Italy |
| 2022-01-17 | FiorentinavGenoaSerie A · Italy | 6–0 | Serie A · Italy |
| 2022-01-10 | TorinovFiorentinaSerie A · Italy | 4–0 | Serie A · Italy |
| 2021-12-22 | VeronavFiorentinaSerie A · Italy | 1–1 | Serie A · Italy |
| 2021-12-19 | FiorentinavSassuoloSerie A · Italy | 2–2 | Serie A · Italy |
| 2021-12-11 | FiorentinavSalernitanaSerie A · Italy | 4–0 | Serie A · Italy |
| 2021-12-05 | BolognavFiorentinaSerie A · Italy | 2–3 | Serie A · Italy |
| 2021-11-30 | FiorentinavSampdoriaSerie A · Italy | 3–1 | Serie A · Italy |
| 2021-11-27 | EmpolivFiorentinaSerie A · Italy | 2–1 | Serie A · Italy |
| 2021-11-20 | FiorentinavMilanSerie A · Italy | 4–3 | Serie A · Italy |
| 2021-11-06 | JuventusvFiorentinaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-10-31 | FiorentinavSpeziaSerie A · Italy | 3–0 | Serie A · Italy |
| 2021-10-27 | LaziovFiorentinaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-10-24 | FiorentinavCagliariSerie A · Italy | 3–0 | Serie A · Italy |
| 2021-10-18 | VeneziavFiorentinaSerie A · Italy | 1–0 | Serie A · Italy |
| 2021-10-03 | FiorentinavNapoliSerie A · Italy | 1–2 | Serie A · Italy |
| 2021-09-26 | UdinesevFiorentinaSerie A · Italy | 0–1 | Serie A · Italy |
| 2021-09-21 | FiorentinavInterSerie A · Italy | 1–3 | Serie A · Italy |
| 2021-09-18 | GenoavFiorentinaSerie A · Italy | 1–2 | Serie A · Italy |
| 2021-09-11 | AtalantavFiorentinaSerie A · Italy | 1–2 | Serie A · Italy |
| 2021-08-28 | FiorentinavTorinoSerie A · Italy | 2–1 | Serie A · Italy |
| 2021-08-22 | RomavFiorentinaSerie A · Italy | 3–1 | Serie A · Italy |
| 2021-05-22 | CrotonevFiorentinaSerie A · Italy | 0–0 | Serie A · Italy |
| 2021-05-16 | FiorentinavNapoliSerie A · Italy | 0–2 | Serie A · Italy |
| 2021-05-12 | CagliarivFiorentinaSerie A · Italy | 0–0 | Serie A · Italy |
| 2021-05-08 | FiorentinavLazioSerie A · Italy | 2–0 | Serie A · Italy |
| 2021-05-02 | BolognavFiorentinaSerie A · Italy | 3–3 | Serie A · Italy |
| 2021-04-25 | FiorentinavJuventusSerie A · Italy | 1–1 | Serie A · Italy |
| 2021-04-20 | VeronavFiorentinaSerie A · Italy | 1–2 | Serie A · Italy |
| 2021-04-17 | SassuolovFiorentinaSerie A · Italy | 3–1 | Serie A · Italy |
| 2021-04-11 | FiorentinavAtalantaSerie A · Italy | 2–3 | Serie A · Italy |
| 2021-04-03 | GenoavFiorentinaSerie A · Italy | 1–1 | Serie A · Italy |