| 2010-10-23 | VaresevTriestinaSerie B · Italy | 4–0 | Serie B · Italy |
| 2010-10-23 | CordobavTenerifeLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2010-10-23 | MillwallvDerbyChampionship · England | 2–0 | Championship · England |
| 2010-10-23 | IngolstadtvFrankfurt FSV2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2010-10-23 | BurnleyvReadingChampionship · England | 0–4 | Championship · England |
| 2010-10-23 | MorecambevStevenageLeague Two · England | 0–0 | League Two · England |
| 2010-10-23 | GrossetovLivornoSerie B · Italy | 0–0 | Serie B · Italy |
| 2010-10-23 | AlbinoleffevPortogruaroSerie B · Italy | 1–0 | Serie B · Italy |
| 2010-10-23 | LincolnvStockportLeague Two · England | 0–0 | League Two · England |
| 2010-10-23 | GillinghamvTorquayLeague Two · England | 1–1 | League Two · England |
| 2010-10-23 | HullvPortsmouthChampionship · England | 1–2 | Championship · England |
| 2010-10-23 | East FifevForfarLeague One · Scotland | 1–3 | League One · Scotland |
| 2010-10-23 | SienavCrotoneSerie B · Italy | 0–0 | Serie B · Italy |
| 2010-10-22 | NovaravVicenzaSerie B · Italy | 3–0 | Serie B · Italy |
| 2010-10-22 | AugsburgvUnion Berlin2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-10-22 | XerezvVillarreal BLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2010-10-22 | NantesvChateaurouxLigue 2 · France | 1–1 | Ligue 2 · France |
| 2010-10-22 | NAC BredavRodaEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2010-10-22 | Le MansvIstresLigue 2 · France | 1–0 | Ligue 2 · France |
| 2010-10-22 | VannesvBoulogneLigue 2 · France | 0–0 | Ligue 2 · France |
| 2010-10-22 | SivassporvBucasporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-10-22 |  Laosv CambodiaAFF Championship qualification | 0–0 | AFF Championship qualification |
| 2010-10-22 | MetzvAngersLigue 2 · France | 1–1 | Ligue 2 · France |
| 2010-10-22 | HerthavGreuther Furth2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-10-22 | KarabuksporvEskisehirsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2010-10-22 |  Timor-Lestev PhilippinesAFF Championship qualification | 0–5 | AFF Championship qualification |
| 2010-10-22 |  Saint Kitts and Nevisv GuadeloupeCFU Caribbean Cup qualification | 1–2 | CFU Caribbean Cup qualification |
| 2010-10-22 | AjacciovToursLigue 2 · France | 2–0 | Ligue 2 · France |
| 2010-10-22 |  Grenadav Puerto RicoCFU Caribbean Cup qualification | 3–1 | CFU Caribbean Cup qualification |
| 2010-10-22 | KortrijkvGenkPro League · Belgium | 1–0 | Pro League · Belgium |
| 2010-10-22 | AcademicavNacionalPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2010-10-22 | OsnabruckvCottbus2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-10-22 | TroyesvClermontLigue 2 · France | 1–1 | Ligue 2 · France |
| 2010-10-22 | Bristol CityvQPRChampionship · England | 1–1 | Championship · England |
| 2010-10-22 | ReimsvGrenobleLigue 2 · France | 4–1 | Ligue 2 · France |
| 2010-10-22 | LavalvDijonLigue 2 · France | 2–0 | Ligue 2 · France |
| 2010-10-22 | HamburgvBayern MunichBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2010-10-19 | SwanseavQPRChampionship · England | 0–0 | Championship · England |
| 2010-10-19 | ChateaurouxvAjaccioLigue 2 · France | 1–2 | Ligue 2 · France |
| 2010-10-19 | CoventryvCardiffChampionship · England | 1–2 | Championship · England |
| 2010-10-19 | BurnleyvBarnsleyChampionship · England | 3–0 | Championship · England |
| 2010-10-19 | HullvSheffield UnitedChampionship · England | 0–1 | Championship · England |
| 2010-10-19 | Bristol CityvReadingChampionship · England | 1–0 | Championship · England |
| 2010-10-19 | WatfordvIpswichChampionship · England | 2–1 | Championship · England |
| 2010-10-19 | LutonvForest GreenNational League · England | 6–1 | National League · England |
| 2010-10-19 | NorwichvCrystal PalaceChampionship · England | 1–2 | Championship · England |
| 2010-10-19 | LeedsvLeicesterChampionship · England | 1–2 | Championship · England |
| 2010-10-19 | PrestonvScunthorpeChampionship · England | 2–3 | Championship · England |
| 2010-10-19 | ToursvReimsLigue 2 · France | 2–1 | Ligue 2 · France |
| 2010-10-19 | AngersvLe MansLigue 2 · France | 1–3 | Ligue 2 · France |