| 2010-10-25 | KayserisporvBesiktasSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-10-25 | Le HavrevNimesLigue 2 · France | 0–0 | Ligue 2 · France |
| 2010-10-25 | Erzgebirge AuevOberhausen2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-10-24 | FenerbahcevGalatasaraySüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2010-10-24 | BolognavJuventusSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-10-24 | ParmavRomaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-10-24 | IntervSampdoriaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-10-24 | TwentevDen HaagEredivisie · Netherlands | 3–2 | Eredivisie · Netherlands |
| 2010-10-24 | StuttgartvSt PauliBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2010-10-24 | GetafevSp GijonLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-10-24 | VitessevUtrechtEredivisie · Netherlands | 1–4 | Eredivisie · Netherlands |
| 2010-10-24 | Sp LisbonvRio AvePrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-10-24 | NumanciavGimnasticLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2010-10-24 | AnkaragucuvBursasporSüper Lig · Turkey | 1–5 | Süper Lig · Turkey |
| 2010-10-24 | GenoavCataniaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-10-24 | AnderlechtvWesterloPro League · Belgium | 2–0 | Pro League · Belgium |
| 2010-10-24 | Paris SGvAuxerreLigue 1 · France | 2–3 | Ligue 1 · France |
| 2010-10-24 | DortmundvHoffenheimBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2010-10-24 | StandardvGentPro League · Belgium | 2–1 | Pro League · Belgium |
| 2010-10-24 |  Guadeloupev Puerto RicoCFU Caribbean Cup qualification | 3–2 | CFU Caribbean Cup qualification |
| 2010-10-24 | AEKvPanathinaikosSuper League · Greece | 1–0 | Super League · Greece |
| 2010-10-24 | SalamancavBetisLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2010-10-24 | ChievovCesenaSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-10-24 |  Grenadav Saint Kitts and NevisCFU Caribbean Cup qualification | 2–0 | CFU Caribbean Cup qualification |
| 2010-10-24 | Man CityvArsenalPremier League · England | 0–3 | Premier League · England |
| 2010-10-24 | PAOKvPanioniosSuper League · Greece | 3–1 | Super League · Greece |
| 2010-10-24 | PanserraikosvKerkyraSuper League · Greece | 0–2 | Super League · Greece |
| 2010-10-24 | KavalavErgotelisSuper League · Greece | 3–1 | Super League · Greece |
| 2010-10-24 | LillevMarseilleLigue 1 · France | 1–3 | Ligue 1 · France |
| 2010-10-24 | SevillavAth BilbaoLa Liga · Spain | 4–3 | La Liga · Spain |
| 2010-10-24 | OlympiakosvArisSuper League · Greece | 1–0 | Super League · Greece |
| 2010-10-24 | MaritimovNavalPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2010-10-24 |  Laosv PhilippinesAFF Championship qualification | 2–2 | AFF Championship qualification |
| 2010-10-24 | PSV EindhovenvFeyenoordEredivisie · Netherlands | 10–0 | Eredivisie · Netherlands |
| 2010-10-24 | LokerenvClub BruggePro League · Belgium | 1–0 | Pro League · Belgium |
| 2010-10-24 | LeccevBresciaSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-10-24 |  Cambodiav Timor-LesteAFF Championship qualification | 4–2 | AFF Championship qualification |
| 2010-10-24 | LiverpoolvBlackburnPremier League · England | 2–1 | Premier League · England |
| 2010-10-24 | DuisburgvKarlsruhe2. Bundesliga · Germany | 3–0 | 2. Bundesliga · Germany |
| 2010-10-24 | ManisasporvKasimpasaSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2010-10-24 | AlmeriavHerculesLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-10-24 | LaziovCagliariSerie A · Italy | 2–1 | Serie A · Italy |
| 2010-10-24 | PortimonensevBenficaPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2010-10-24 | ExcelsiorvAjaxEredivisie · Netherlands | 2–2 | Eredivisie · Netherlands |
| 2010-10-24 | LeverkusenvMainzBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2010-10-24 | ArlesvLyonLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-10-24 | VillarrealvAth MadridLa Liga · Spain | 2–0 | La Liga · Spain |
| 2010-10-24 | OsasunavMalagaLa Liga · Spain | 3–0 | La Liga · Spain |
| 2010-10-24 | StokevMan UnitedPremier League · England | 1–2 | Premier League · England |
| 2010-10-24 | AZ AlkmaarvWillem IIEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |