| 2009-10-26 | ReadingvLeicesterChampionship · England | 0–1 | Championship · England |
| 2009-10-26 | BenficavNacionalPrimeira Liga · Portugal | 6–1 | Primeira Liga · Portugal |
| 2009-10-26 | GuingampvLe HavreLigue 2 · France | 1–2 | Ligue 2 · France |
| 2009-10-25 | ValladolidvLa CorunaLa Liga · Spain | 4–0 | La Liga · Spain |
| 2009-10-25 | BoltonvEvertonPremier League · England | 3–2 | Premier League · England |
| 2009-10-25 | HerthavWolfsburgBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2009-10-25 | AlmeriavValenciaLa Liga · Spain | 0–3 | La Liga · Spain |
| 2009-10-25 | ElchevCartagenaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2009-10-25 | AtalantavParmaSerie A · Italy | 3–1 | Serie A · Italy |
| 2009-10-25 | BarcelonavZaragozaLa Liga · Spain | 6–1 | La Liga · Spain |
| 2009-10-25 | FiorentinavNapoliSerie A · Italy | 0–1 | Serie A · Italy |
| 2009-10-25 | TwentevGroningenEredivisie · Netherlands | 4–0 | Eredivisie · Netherlands |
| 2009-10-25 | CagliarivGenoaSerie A · Italy | 3–2 | Serie A · Italy |
| 2009-10-25 | ChievovMilanSerie A · Italy | 1–2 | Serie A · Italy |
| 2009-10-25 | KasimpasavDenizlisporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2009-10-25 | BarivLazioSerie A · Italy | 2–0 | Serie A · Italy |
| 2009-10-25 | AachenvUnion Berlin2. Bundesliga · Germany | 1–4 | 2. Bundesliga · Germany |
| 2009-10-25 | VillarrealvMalagaLa Liga · Spain | 2–1 | La Liga · Spain |
| 2009-10-25 | RomavLivornoSerie A · Italy | 0–1 | Serie A · Italy |
| 2009-10-25 | NumanciavSalamancaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2009-10-25 | FenerbahcevGalatasaraySüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2009-10-25 | Willem IIvHeerenveenEredivisie · Netherlands | 4–1 | Eredivisie · Netherlands |
| 2009-10-25 | PortovAcademicaPrimeira Liga · Portugal | 3–2 | Primeira Liga · Portugal |
| 2009-10-25 | KarlsruhevOberhausen2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2009-10-25 | ArisvAEKSuper League · Greece | 1–1 | Super League · Greece |
| 2009-10-25 | XanthivKavalaSuper League · Greece | 2–1 | Super League · Greece |
| 2009-10-25 | PanathinaikosvPAOKSuper League · Greece | 2–1 | Super League · Greece |
| 2009-10-25 | HamiltonvCelticPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2009-10-25 | CadizvReal UnionLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2009-10-25 | St PaulivCottbus2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2009-10-25 | SetubalvLeixoesPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2009-10-25 | Man CityvFulhamPremier League · England | 2–2 | Premier League · England |
| 2009-10-25 | NijmegenvPSV EindhovenEredivisie · Netherlands | 0–4 | Eredivisie · Netherlands |
| 2009-10-25 | AuxerrevLilleLigue 1 · France | 3–2 | Ligue 1 · France |
| 2009-10-25 | PanthrakikosvLarisaSuper League · Greece | 1–3 | Super League · Greece |
| 2009-10-25 |  Namibiav ZambiaCOSAFA Cup | 0–1 | COSAFA Cup |
| 2009-10-25 | SantandervOsasunaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2009-10-25 | West HamvArsenalPremier League · England | 2–2 | Premier League · England |
| 2009-10-25 | ManisasporvAntalyasporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2009-10-25 | TenerifevXerezLa Liga · Spain | 1–0 | La Liga · Spain |
| 2009-10-25 | GetafevAth BilbaoLa Liga · Spain | 2–0 | La Liga · Spain |
| 2009-10-25 | BochumvWerder BremenBundesliga · Germany | 1–4 | Bundesliga · Germany |
| 2009-10-25 | MechelenvAnderlechtPro League · Belgium | 0–2 | Pro League · Belgium |
| 2009-10-25 | LensvToulouseLigue 1 · France | 0–2 | Ligue 1 · France |
| 2009-10-25 | MaritimovPacos FerreiraPrimeira Liga · Portugal | 3–1 | Primeira Liga · Portugal |
| 2009-10-25 |  Malawiv MozambiqueCOSAFA Cup | 0–1 | COSAFA Cup |
| 2009-10-25 | Schalke 04vHamburgBundesliga · Germany | 3–3 | Bundesliga · Germany |
| 2009-10-25 | RoeselarevClub BruggePro League · Belgium | 2–3 | Pro League · Belgium |
| 2009-10-25 | LevadeiakosvIraklisSuper League · Greece | 1–0 | Super League · Greece |
| 2009-10-25 | LiverpoolvMan UnitedPremier League · England | 2–0 | Premier League · England |