| 2016-11-19 | EvertonvSwanseaPremier League · England | 1–1 | Premier League · England |
| 2016-11-19 | LecznavRuchEkstraklasa · Poland | 0–4 | Ekstraklasa · Poland |
| 2016-11-19 | Willem IIvPSV EindhovenEredivisie · Netherlands | 0–0 | Eredivisie · Netherlands |
| 2016-11-19 | OrenburgvLokomotiv MoscowPremier League · Russia | 1–1 | Premier League · Russia |
| 2016-11-19 | AFC WimbledonvBuryLeague One · England | 5–1 | League One · England |
| 2016-11-19 | RennesvAngersLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-11-19 | MallorcavSevilla BLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2016-11-19 | Ath MadridvReal MadridLa Liga · Spain | 0–3 | La Liga · Spain |
| 2016-11-19 | MansfieldvCrawley TownLeague Two · England | 3–1 | League Two · England |
| 2016-11-19 | SouthamptonvLiverpoolPremier League · England | 0–0 | Premier League · England |
| 2016-11-19 | BirminghamvBristol CityChampionship · England | 1–0 | Championship · England |
| 2016-11-19 | TorquayvWrexhamNational League · England | 1–1 | National League · England |
| 2016-11-19 | KarlsruhevSandhausen2. Bundesliga · Germany | 1–3 | 2. Bundesliga · Germany |
| 2016-11-19 | SunderlandvHullPremier League · England | 3–0 | Premier League · England |
| 2016-11-19 | WalsallvGillinghamLeague One · England | 1–2 | League One · England |
| 2016-11-19 | Dover AthleticvGuiseleyNational League · England | 2–0 | National League · England |
| 2016-11-19 | Poli IasivTargu MuresSuperliga · Romania | 0–0 | Superliga · Romania |
| 2016-11-19 | Arsenal SarandivBanfieldLiga Profesional · Argentina | 1–3 | Liga Profesional · Argentina |
| 2016-11-19 | HeerenveenvVitesseEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2016-11-19 | Man UnitedvArsenalPremier League · England | 1–1 | Premier League · England |
| 2016-11-19 | St JohnstonevRoss CountyPremiership · Scotland | 2–4 | Premiership · Scotland |
| 2016-11-19 | BastiavMontpellierLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-11-19 | Braintree TownvTranmereNational League · England | 0–1 | National League · England |
| 2016-11-19 | AyrvFalkirkChampionship · Scotland | 0–1 | Championship · Scotland |
| 2016-11-19 | MotherwellvPartickPremiership · Scotland | 2–0 | Premiership · Scotland |
| 2016-11-19 | Estudiantes L.P.vColon Santa FELiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-11-18 | AuxerrevLensLigue 2 · France | 1–1 | Ligue 2 · France |
| 2016-11-18 | Red StarvTroyesLigue 2 · France | 1–2 | Ligue 2 · France |
| 2016-11-18 | LillevLyonLigue 1 · France | 0–1 | Ligue 1 · France |
| 2016-11-18 | FC BotosanivFC VoluntariSuperliga · Romania | 0–1 | Superliga · Romania |
| 2016-11-18 | PanduriivPoli TimisoaraSuperliga · Romania | 2–2 | Superliga · Romania |
| 2016-11-18 | BrightonvAston VillaChampionship · England | 1–1 | Championship · England |
| 2016-11-18 | St TruidenvClub BruggePro League · Belgium | 0–1 | Pro League · Belgium |
| 2016-11-18 | KilmarnockvCelticPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2016-11-18 | LeverkusenvRB LeipzigBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2016-11-18 | LyngbyvHorsensSuperliga · Denmark | 0–1 | Superliga · Denmark |
| 2016-11-18 | CittadellavVeronaSerie B · Italy | 5–1 | Serie B · Italy |
| 2016-11-18 | ValenciennesvBourg PeronnasLigue 2 · France | 3–3 | Ligue 2 · France |
| 2016-11-18 | Lorientv MonacoLigue 1 · France | 0–3 | Ligue 1 · France |
| 2016-11-18 | BetisvLas PalmasLa Liga · Spain | 2–0 | La Liga · Spain |
| 2016-11-18 | BielefeldvHeidenheim2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2016-11-18 | ClermontvAjaccio GFCOLigue 2 · France | 3–1 | Ligue 2 · France |
| 2016-11-18 | Arsenal TulavCSKA MoscowPremier League · Russia | 0–1 | Premier League · Russia |
| 2016-11-18 | AjacciovStrasbourgLigue 2 · France | 2–0 | Ligue 2 · France |
| 2016-11-18 | OrleansvNimesLigue 2 · France | 2–1 | Ligue 2 · France |
| 2016-11-18 | Rubin KazanvFK RostovPremier League · Russia | 0–0 | Premier League · Russia |
| 2016-11-18 | Piast GliwicevCracoviaEkstraklasa · Poland | 2–2 | Ekstraklasa · Poland |
| 2016-11-18 | ReimsvLavalLigue 2 · France | 0–2 | Ligue 2 · France |
| 2016-11-18 | NurnbergvWurzburger Kickers2. Bundesliga · Germany | 2–2 | 2. Bundesliga · Germany |
| 2016-11-18 | JagielloniavLegiaEkstraklasa · Poland | 1–4 | Ekstraklasa · Poland |