| 2010-12-21 | AngersvToursLigue 2 · France | 2–2 | Ligue 2 · France |
| 2010-12-21 | IstresvAjaccioLigue 2 · France | 2–2 | Ligue 2 · France |
| 2010-12-21 | NimesvMetzLigue 2 · France | 2–0 | Ligue 2 · France |
| 2010-12-21 | BoulognevDijonLigue 2 · France | 0–1 | Ligue 2 · France |
| 2010-12-21 | ClermontvGrenobleLigue 2 · France | 2–2 | Ligue 2 · France |
| 2010-12-21 | Le MansvVannesLigue 2 · France | 0–1 | Ligue 2 · France |
| 2010-12-21 | CelticvKilmarnockPremiership · Scotland | 1–1 | Premiership · Scotland |
| 2010-12-21 | LorientvMontpellierLigue 1 · France | 0–0 | Ligue 1 · France |
| 2010-12-20 | Le HavrevNantesLigue 2 · France | 0–1 | Ligue 2 · France |
| 2010-12-20 | SantandervHerculesLa Liga · Spain | 0–0 | La Liga · Spain |
| 2010-12-20 | SetubalvSp LisbonPrimeira Liga · Portugal | 0–3 | Primeira Liga · Portugal |
| 2010-12-20 | Union BerlinvKarlsruhe2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2010-12-20 | Man CityvEvertonPremier League · England | 1–2 | Premier League · England |
| 2010-12-20 | AlbinoleffevPiacenzaSerie B · Italy | 3–3 | Serie B · Italy |
| 2010-12-19 | Barcelona BvPonferradinaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2010-12-19 | OlhanensevNacionalPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2010-12-19 | KasimpasavEskisehirsporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2010-12-19 | NapolivLecceSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-12-19 | ManisasporvBuyuksehyrSüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2010-12-19 | Pacos FerreiravPortoPrimeira Liga · Portugal | 0–3 | Primeira Liga · Portugal |
| 2010-12-19 | SochauxvBordeauxLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-12-19 | LarisavOlympiakosSuper League · Greece | 0–1 | Super League · Greece |
| 2010-12-19 | MaritimovPortimonensePrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2010-12-19 | KonyasporvGalatasaraySüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2010-12-19 | BesiktasvGaziantepsporSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-12-19 | BarivPalermoSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-12-19 | ParmavBolognaSerie A · Italy | 0–0 | Serie A · Italy |
| 2010-12-19 |  Indonesiav PhilippinesAFF Championship | 1–0 | AFF Championship |
| 2010-12-19 | Real MadridvSevillaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-12-19 | LaziovUdineseSerie A · Italy | 3–2 | Serie A · Italy |
| 2010-12-19 | NavalvLeiriaPrimeira Liga · Portugal | 0–3 | Primeira Liga · Portugal |
| 2010-12-19 | MarseillevLyonLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-12-19 | LeverkusenvFreiburgBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2010-12-19 | KerkyravPAOKSuper League · Greece | 2–1 | Super League · Greece |
| 2010-12-19 | CartagenavLas PalmasLa Liga 2 · Spain | 5–2 | La Liga 2 · Spain |
| 2010-12-19 | Club BruggevAnderlechtPro League · Belgium | 0–2 | Pro League · Belgium |
| 2010-12-19 | AlmeriavGetafeLa Liga · Spain | 2–3 | La Liga · Spain |
| 2010-12-19 | PSV EindhovenvRodaEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2010-12-19 | IraklisvAEKSuper League · Greece | 2–0 | Super League · Greece |
| 2010-12-19 | OsnabruckvIngolstadt2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2010-12-19 | OberhausenvCottbus2. Bundesliga · Germany | 0–4 | 2. Bundesliga · Germany |
| 2010-12-19 | StuttgartvBayern MunichBundesliga · Germany | 3–5 | Bundesliga · Germany |
| 2010-12-19 | MalagavAth MadridLa Liga · Spain | 0–3 | La Liga · Spain |
| 2010-12-19 | ChievovJuventusSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-12-19 | ArisvXanthiSuper League · Greece | 0–2 | Super League · Greece |
| 2010-12-19 | OsasunavZaragozaLa Liga · Spain | 0–0 | La Liga · Spain |
| 2010-12-19 | Munich 1860vPaderborn2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2010-12-19 | CataniavBresciaSerie A · Italy | 1–0 | Serie A · Italy |
| 2010-12-18 | La CorunavSp GijonLa Liga · Spain | 1–1 | La Liga · Spain |
| 2010-12-18 | HeartsvInverness CPremiership · Scotland | 1–1 | Premiership · Scotland |