| 2000-12-23 | DarlingtonvLincolnLeague Two · England | 3–0 | League Two · England |
| 2000-12-23 | DerbyvNewcastlePremier League · England | 2–0 | Premier League · England |
| 2000-12-23 | BrentfordvOldhamLeague One · England | 1–1 | League One · England |
| 2000-12-23 | DundeevAberdeenPremiership · Scotland | 2–2 | Premiership · Scotland |
| 2000-12-23 | West BromvNott'm ForestChampionship · England | 3–0 | Championship · England |
| 2000-12-23 | CittadellavSalernitanaSerie B · Italy | 1–1 | Serie B · Italy |
| 2000-12-23 | EmpolivMonzaSerie B · Italy | 4–2 | Serie B · Italy |
| 2000-12-23 | WycombevSwanseaLeague One · England | 2–1 | League One · England |
| 2000-12-23 | HullvKidderminsterLeague Two · England | 0–0 | League Two · England |
| 2000-12-23 | LeedsvAston VillaPremier League · England | 1–2 | Premier League · England |
| 2000-12-23 | BournemouthvMillwallLeague One · England | 1–2 | League One · England |
| 2000-12-23 | CrewevFulhamChampionship · England | 1–2 | Championship · England |
| 2000-12-23 | BurnleyvBoltonChampionship · England | 0–2 | Championship · England |
| 2000-12-23 | WatfordvHuddersfieldChampionship · England | 1–2 | Championship · England |
| 2000-12-23 | AtalantavInterSerie A · Italy | 0–1 | Serie A · Italy |
| 2000-12-23 | SunderlandvMan CityPremier League · England | 1–0 | Premier League · England |
| 2000-12-23 | Sheffield WedsvWolvesChampionship · England | 0–1 | Championship · England |
| 2000-12-23 | HartlepoolvBarnetLeague Two · England | 6–1 | League Two · England |
| 2000-12-23 | RangersvHibernianPremiership · Scotland | 1–0 | Premiership · Scotland |
| 2000-12-23 | Leyton OrientvRochdaleLeague Two · England | 1–1 | League Two · England |
| 2000-12-23 | GaziantepsporvBursasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2000-12-23 | SampdoriavPiacenzaSerie B · Italy | 0–1 | Serie B · Italy |
| 2000-12-23 | ClydebankvArbroathLeague One · Scotland | 1–2 | League One · Scotland |
| 2000-12-23 | HalifaxvPlymouthLeague Two · England | 2–0 | League Two · England |
| 2000-12-23 | FiorentinavVeronaSerie A · Italy | 2–0 | Serie A · Italy |
| 2000-12-23 | CharltonvEvertonPremier League · England | 1–0 | Premier League · England |
| 2000-12-23 | BirminghamvQPRChampionship · England | 0–0 | Championship · England |
| 2000-12-23 | YozgatsporvBesiktasSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2000-12-23 | HeartsvDundee UnitedPremiership · Scotland | 3–1 | Premiership · Scotland |
| 2000-12-23 | RavennavAnconaSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-12-23 | WiganvStokeLeague One · England | 1–1 | League One · England |
| 2000-12-23 | LeicestervWest HamPremier League · England | 2–1 | Premier League · England |
| 2000-12-23 | BresciavLecceSerie A · Italy | 2–2 | Serie A · Italy |
| 2000-12-23 | St JohnstonevMotherwellPremiership · Scotland | 2–3 | Premiership · Scotland |
| 2000-12-23 | WalsallvCambridgeLeague One · England | 3–1 | League One · England |
| 2000-12-23 | TottenhamvMiddlesbroughPremier League · England | 0–0 | Premier League · England |
| 2000-12-23 | AntalyasporvSiirt Jet-PASüper Lig · Turkey | 1–3 | Süper Lig · Turkey |
| 2000-12-23 | CagliarivSienaSerie B · Italy | 0–0 | Serie B · Italy |
| 2000-12-23 | PrestonvGrimsbyChampionship · England | 1–2 | Championship · England |
| 2000-12-23 | ScunthorpevCheltenhamLeague Two · England | 1–1 | League Two · England |
| 2000-12-23 | GalatasarayvDenizlisporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2000-12-23 | CardiffvMacclesfieldLeague Two · England | 2–0 | League Two · England |
| 2000-12-23 | Inverness CvClydeChampionship · Scotland | 2–2 | Championship · Scotland |
| 2000-12-23 | Notts CountyvWrexhamLeague One · England | 1–0 | League One · England |
| 2000-12-23 | St MirrenvCelticPremiership · Scotland | 0–2 | Premiership · Scotland |
| 2000-12-23 | Queen of SthvQueens ParkLeague One · Scotland | 1–1 | League One · Scotland |
| 2000-12-23 | PistoiesevCosenzaSerie B · Italy | 1–1 | Serie B · Italy |
| 2000-12-23 | ChievovVeneziaSerie B · Italy | 2–1 | Serie B · Italy |
| 2000-12-22 | Bristol CityvBristol RvsLeague One · England | 3–2 | League One · England |
| 2000-12-22 | AnkaragucuvSamsunsporSüper Lig · Turkey | 2–0 | Süper Lig · Turkey |