| 2010-11-06 | GironavPonferradinaLa Liga 2 · Spain | 3–0 | La Liga 2 · Spain |
| 2010-11-06 | ForfarvPeterheadLeague One · Scotland | 1–1 | League One · Scotland |
| 2010-11-06 | IntervBresciaSerie A · Italy | 1–1 | Serie A · Italy |
| 2010-11-06 | AyrvAirdrie UtdLeague One · Scotland | 1–0 | League One · Scotland |
| 2010-11-06 | ArbroathvBerwickLeague Two · Scotland | 3–2 | League Two · Scotland |
| 2010-11-06 | Barcelona BvVillarreal BLa Liga 2 · Spain | 4–1 | La Liga 2 · Spain |
| 2010-11-06 | AntalyasporvBursasporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2010-11-06 | DundeevPartickChampionship · Scotland | 2–1 | Championship · Scotland |
| 2010-11-06 | MechelenvCharleroiPro League · Belgium | 2–0 | Pro League · Belgium |
| 2010-11-06 | MiddlesbroughvCrystal PalaceChampionship · England | 2–1 | Championship · England |
| 2010-11-06 | LivingstonvDumbartonLeague One · Scotland | 2–0 | League One · Scotland |
| 2010-11-06 | NumanciavAlcorconLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2010-11-06 | KortrijkvGerminalPro League · Belgium | 4–0 | Pro League · Belgium |
| 2010-11-06 | HamburgvHoffenheimBundesliga · Germany | 2–1 | Bundesliga · Germany |
| 2010-11-06 | BlackpoolvEvertonPremier League · England | 2–2 | Premier League · England |
| 2010-11-06 | KarabuksporvBucasporSüper Lig · Turkey | 3–0 | Süper Lig · Turkey |
| 2010-11-06 | HullvScunthorpeChampionship · England | 0–1 | Championship · England |
| 2010-11-06 | SienavFrosinoneSerie B · Italy | 3–0 | Serie B · Italy |
| 2010-11-06 | FulhamvAston VillaPremier League · England | 1–1 | Premier League · England |
| 2010-11-06 | DuisburgvGreuther Furth2. Bundesliga · Germany | 2–0 | 2. Bundesliga · Germany |
| 2010-11-06 | Olympiakos VolouvKerkyraSuper League · Greece | 1–0 | Super League · Greece |
| 2010-11-06 | SochauxvAuxerreLigue 1 · France | 1–1 | Ligue 1 · France |
| 2010-11-06 | GrossetovTorinoSerie B · Italy | 0–0 | Serie B · Italy |
| 2010-11-06 | Pacos FerreiravNacionalPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2010-11-06 | NurnbergvFC KolnBundesliga · Germany | 3–1 | Bundesliga · Germany |
| 2010-11-06 | ClydevEast StirlingLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2010-11-06 | AnkaragucuvGaziantepsporSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2010-11-06 | FreiburgvMainzBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2010-11-06 | WatfordvNott'm ForestChampionship · England | 1–1 | Championship · England |
| 2010-11-06 | NorwichvBurnleyChampionship · England | 2–2 | Championship · England |
| 2010-11-06 |  Vietnamv North KoreaVFF Cup | 0–2 | VFF Cup |
| 2010-11-06 | CrotonevPescaraSerie B · Italy | 0–1 | Serie B · Italy |
| 2010-11-06 | EspanolvMalagaLa Liga · Spain | 1–0 | La Liga · Spain |
| 2010-11-05 | ReimsvAngersLigue 2 · France | 2–0 | Ligue 2 · France |
| 2010-11-05 | Erzgebirge AuevFortuna Dusseldorf2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2010-11-05 | RegginavPortogruaroSerie B · Italy | 1–0 | Serie B · Italy |
| 2010-11-05 | BochumvFrankfurt FSV2. Bundesliga · Germany | 1–0 | 2. Bundesliga · Germany |
| 2010-11-05 | Willem IIvVVV VenloEredivisie · Netherlands | 1–4 | Eredivisie · Netherlands |
| 2010-11-05 | KayserisporvGenclerbirligiSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2010-11-05 | NantesvNimesLigue 2 · France | 2–1 | Ligue 2 · France |
| 2010-11-05 | Schalke 04vSt PauliBundesliga · Germany | 3–0 | Bundesliga · Germany |
| 2010-11-05 | SetubalvRio AvePrimeira Liga · Portugal | 3–3 | Primeira Liga · Portugal |
| 2010-11-05 | IngolstadtvCottbus2. Bundesliga · Germany | 1–2 | 2. Bundesliga · Germany |
| 2010-11-05 | VannesvClermontLigue 2 · France | 1–1 | Ligue 2 · France |
| 2010-11-05 | Evian Thonon GaillardvLe HavreLigue 2 · France | 1–1 | Ligue 2 · France |
| 2010-11-05 | ElchevLas PalmasLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2010-11-05 | AjacciovDijonLigue 2 · France | 1–0 | Ligue 2 · France |
| 2010-11-05 | ChateaurouxvGrenobleLigue 2 · France | 4–3 | Ligue 2 · France |
| 2010-11-05 | WesterlovGenkPro League · Belgium | 1–1 | Pro League · Belgium |
| 2010-11-05 | TriestinavAtalantaSerie B · Italy | 0–1 | Serie B · Italy |