| 2000-11-05 | Ath MadridvTenerifeLa Liga 2 · Spain | 1–2 | La Liga 2 · Spain |
| 2000-11-05 | VeneziavPescaraSerie B · Italy | 1–1 | Serie B · Italy |
| 2000-11-05 | BresciavRomaSerie A · Italy | 2–4 | Serie A · Italy |
| 2000-11-05 | RoosendaalvFor SittardEredivisie · Netherlands | 3–1 | Eredivisie · Netherlands |
| 2000-11-05 | FeyenoordvRoda JCEredivisie · Netherlands | 4–2 | Eredivisie · Netherlands |
| 2000-11-05 | SociedadvMallorcaLa Liga · Spain | 0–1 | La Liga · Spain |
| 2000-11-05 | Greuther FurthvMannheim2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2000-11-05 | AlavesvOviedoLa Liga · Spain | 4–0 | La Liga · Spain |
| 2000-11-05 | UnterhachingvFC KolnBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2000-11-05 | UtrechtvSpartaEredivisie · Netherlands | 1–1 | Eredivisie · Netherlands |
| 2000-11-05 | WolfsburgvCottbusBundesliga · Germany | 1–1 | Bundesliga · Germany |
| 2000-11-05 | CordobavU.Las PalmasLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2000-11-05 | YozgatsporvErzurumsporSüper Lig · Turkey | 4–0 | Süper Lig · Turkey |
| 2000-11-05 | AnconavSalernitanaSerie B · Italy | 4–1 | Serie B · Italy |
| 2000-11-05 | VallecanovValladolidLa Liga · Spain | 2–1 | La Liga · Spain |
| 2000-11-05 | RegginavJuventusSerie A · Italy | 0–2 | Serie A · Italy |
| 2000-11-05 | CompostelavSalamancaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2000-11-05 | EmpolivTrevisoSerie B · Italy | 2–1 | Serie B · Italy |
| 2000-11-05 | PistoiesevChievoSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-11-05 | Willem IIvAjaxEredivisie · Netherlands | 0–1 | Eredivisie · Netherlands |
| 2000-11-05 | TorinovSienaSerie B · Italy | 1–1 | Serie B · Italy |
| 2000-11-05 |  Singaporev CambodiaAFF Championship | 1–0 | AFF Championship |
| 2000-11-05 |  Vietnamv MalaysiaAFF Championship | 0–0 | AFF Championship |
| 2000-11-05 | GetafevAlbaceteLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2000-11-05 | NapolivVicenzaSerie A · Italy | 1–2 | Serie A · Italy |
| 2000-11-05 | CampomaiorensevBelenensesPrimeira Liga · Portugal | 0–1 | Primeira Liga · Portugal |
| 2000-11-05 | PAOKvOFISuper League · Greece | 4–1 | Super League · Greece |
| 2000-11-05 | MonzavCrotoneSerie B · Italy | 0–1 | Serie B · Italy |
| 2000-11-05 | ZaragozavSantanderLa Liga · Spain | 2–0 | La Liga · Spain |
| 2000-11-05 | EvertonvAston VillaPremier League · England | 0–1 | Premier League · England |
| 2000-11-05 | GraafschapvVitesseEredivisie · Netherlands | 1–2 | Eredivisie · Netherlands |
| 2000-11-05 | PiacenzavTernanaSerie B · Italy | 3–0 | Serie B · Italy |
| 2000-11-05 | MaritimovBenficaPrimeira Liga · Portugal | 3–0 | Primeira Liga · Portugal |
| 2000-11-05 | CosenzavCittadellaSerie B · Italy | 1–0 | Serie B · Italy |
| 2000-11-05 | SalgueirosvAvesPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2000-11-05 | KilmarnockvCelticPremiership · Scotland | 0–1 | Premiership · Scotland |
| 2000-11-05 | PanioniosvIraklisSuper League · Greece | 1–1 | Super League · Greece |
| 2000-11-05 | DundeevHibernianPremiership · Scotland | 1–2 | Premiership · Scotland |
| 2000-11-05 | LavalvLe HavreLigue 2 · France | 1–0 | Ligue 2 · France |
| 2000-11-05 | PanathinaikosvPaniliakosSuper League · Greece | 2–0 | Super League · Greece |
| 2000-11-05 | BadajozvExtremaduraLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2000-11-05 | OsasunavAth BilbaoLa Liga · Spain | 1–1 | La Liga · Spain |
| 2000-11-05 | OsnabruckvSt Pauli2. Bundesliga · Germany | 0–0 | 2. Bundesliga · Germany |
| 2000-11-05 | ElchevSp GijonLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2000-11-05 | RavennavCagliariSerie B · Italy | 2–4 | Serie B · Italy |
| 2000-11-05 | XanthivArisSuper League · Greece | 1–0 | Super League · Greece |
| 2000-11-05 | FerrolvEibarLa Liga 2 · Spain | 0–1 | La Liga 2 · Spain |
| 2000-11-05 | Siirt Jet-PAvSamsunsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2000-11-05 | RecreativovLleidaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2000-11-05 | UlmvAachen2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |