| 2021-01-02 | GalatasarayvAntalyasporSüper Lig · Turkey | 0–0 | Süper Lig · Turkey |
| 2021-01-02 | HibernianvLivingstonPremiership · Scotland | 0–3 | Premiership · Scotland |
| 2021-01-02 | BarnetvBoreham WoodNational League · England | 0–3 | National League · England |
| 2021-01-02 | StockportvAltrinchamNational League · England | 2–2 | National League · England |
| 2021-01-02 | AberdeenvDundee UnitedPremiership · Scotland | 0–0 | Premiership · Scotland |
| 2021-01-02 | AnkaragucuvYeni MalatyasporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2021-01-02 | StuttgartvRB LeipzigBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2021-01-02 | PlymouthvGillinghamLeague One · England | 1–0 | League One · England |
| 2021-01-02 | Rosario CentralvDefensa y JusticiaCopa De La Liga Profesional · Argentina | 3–0 | Copa De La Liga Profesional · Argentina |
| 2021-01-02 | MillwallvCoventryChampionship · England | 1–2 | Championship · England |
| 2021-01-02 | StokevBournemouthChampionship · England | 0–1 | Championship · England |
| 2021-01-02 | VillarrealvLevanteLa Liga · Spain | 2–1 | La Liga · Spain |
| 2021-01-02 | BetisvSevillaLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-01-02 | GrimsbyvCambridgeLeague Two · England | 1–2 | League Two · England |
| 2021-01-02 | Leyton OrientvSalfordLeague Two · England | 1–0 | League Two · England |
| 2021-01-02 | BirminghamvBlackburnChampionship · England | 0–2 | Championship · England |
| 2021-01-02 | Real MadridvCeltaLa Liga · Spain | 2–0 | La Liga · Spain |
| 2021-01-02 | West BromvArsenalPremier League · England | 0–4 | Premier League · England |
| 2021-01-02 | TottenhamvLeedsPremier League · England | 3–0 | Premier League · England |
| 2021-01-02 | Queen of SthvAyrChampionship · Scotland | 3–2 | Championship · Scotland |
| 2021-01-02 | MansfieldvPort ValeLeague Two · England | 4–0 | League Two · England |
| 2021-01-02 | CartagenavZaragozaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2021-01-02 | East FifevFalkirkLeague One · Scotland | 2–1 | League One · Scotland |
| 2021-01-02 | AlloavMortonChampionship · Scotland | 1–1 | Championship · Scotland |
| 2021-01-02 | Werder BremenvUnion BerlinBundesliga · Germany | 0–2 | Bundesliga · Germany |
| 2021-01-02 | DundeevHeartsChampionship · Scotland | 3–1 | Championship · Scotland |
| 2021-01-02 | HataysporvKonyasporSüper Lig · Turkey | 2–1 | Süper Lig · Turkey |
| 2021-01-02 | Ross CountyvSt JohnstonePremiership · Scotland | 1–1 | Premiership · Scotland |
| 2021-01-02 | Cove RangersvPeterheadLeague One · Scotland | 1–0 | League One · Scotland |
| 2021-01-02 | MontrosevForfarLeague One · Scotland | 0–0 | League One · Scotland |
| 2021-01-02 | StranraervAnnan AthleticLeague Two · Scotland | 2–0 | League Two · Scotland |
| 2021-01-02 | HuddersfieldvReadingChampionship · England | 1–2 | Championship · England |
| 2021-01-02 | BochumvDarmstadt2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2021-01-02 | SwanseavWatfordChampionship · England | 2–1 | Championship · England |
| 2021-01-02 | Bristol RvsvBlackpoolLeague One · England | 2–1 | League One · England |
| 2021-01-02 | Crystal PalacevSheffield UnitedPremier League · England | 2–0 | Premier League · England |
| 2021-01-02 | FC KolnvAugsburgBundesliga · Germany | 0–1 | Bundesliga · Germany |
| 2021-01-02 | Erzurum BBvGaziantepSüper Lig · Turkey | 1–1 | Süper Lig · Turkey |
| 2021-01-02 | StevenagevScunthorpeLeague Two · England | 3–1 | League Two · England |
| 2021-01-01 | Sheffield WedsvDerbyChampionship · England | 1–0 | Championship · England |
| 2021-01-01 | Man UnitedvAston VillaPremier League · England | 2–1 | Premier League · England |
| 2021-01-01 | EvertonvWest HamPremier League · England | 0–1 | Premier League · England |