| 2021-01-05 | SolihullvChesterfieldNational League · England | 2–1 | National League · England |
| 2021-01-04 | VeneziavPisaSerie B · Italy | 1–1 | Serie B · Italy |
| 2021-01-04 | CremonesevChievoSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-01-04 | AscolivRegginaSerie B · Italy | 2–1 | Serie B · Italy |
| 2021-01-04 | LamiavArisSuper League · Greece | 2–0 | Super League · Greece |
| 2021-01-04 | SouthamptonvLiverpoolPremier League · England | 1–0 | Premier League · England |
| 2021-01-04 | Santa ClaravBenficaPrimeira Liga · Portugal | 1–1 | Primeira Liga · Portugal |
| 2021-01-04 | Central CordobavRacing ClubCopa De La Liga Profesional · Argentina | 2–2 | Copa De La Liga Profesional · Argentina |
| 2021-01-04 | LugovSp GijonLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2021-01-04 | San LorenzovGimnasia L.P.Copa De La Liga Profesional · Argentina | 1–2 | Copa De La Liga Profesional · Argentina |
| 2021-01-04 | ReggianavPescaraSerie B · Italy | 0–1 | Serie B · Italy |
| 2021-01-04 | BresciavVicenzaSerie B · Italy | 0–3 | Serie B · Italy |
| 2021-01-04 | KasimpasavFenerbahceSüper Lig · Turkey | 0–3 | Süper Lig · Turkey |
| 2021-01-04 | LeccevMonzaSerie B · Italy | 0–0 | Serie B · Italy |
| 2021-01-04 | SalernitanavPordenoneSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-01-04 | CosenzavEmpoliSerie B · Italy | 0–2 | Serie B · Italy |
| 2021-01-04 | Virtus EntellavCittadellaSerie B · Italy | 1–0 | Serie B · Italy |
| 2021-01-04 | GironavSabadellLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2021-01-04 | AldosivivUnion de Santa FeCopa De La Liga Profesional · Argentina | 1–3 | Copa De La Liga Profesional · Argentina |
| 2021-01-04 | FrosinonevSpalSerie B · Italy | 1–2 | Serie B · Italy |
| 2021-01-04 | Volos NFCvAtromitosSuper League · Greece | 1–0 | Super League · Greece |
| 2021-01-04 | PortimonensevFarensePrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-01-04 | Gil VicentevBelenensesPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2021-01-04 | ValenciavCadizLa Liga · Spain | 1–1 | La Liga · Spain |
| 2021-01-04 | Fortuna DusseldorfvPaderborn2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2021-01-03 | Greuther FurthvSt Pauli2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |
| 2021-01-03 | HamburgvRegensburg2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2021-01-03 | AlmeriavPonferradinaLa Liga 2 · Spain | 3–1 | La Liga 2 · Spain |
| 2021-01-03 | SpeziavVeronaSerie A · Italy | 0–1 | Serie A · Italy |
| 2021-01-03 | PanathinaikosvAsteras TripolisSuper League · Greece | 0–0 | Super League · Greece |
| 2021-01-03 | IntervCrotoneSerie A · Italy | 6–2 | Serie A · Italy |
| 2021-01-03 | HannovervSandhausen2. Bundesliga · Germany | 4–0 | 2. Bundesliga · Germany |
| 2021-01-03 | PatronatovLanusCopa De La Liga Profesional · Argentina | 1–1 | Copa De La Liga Profesional · Argentina |
| 2021-01-03 | Newells Old BoysvVelez SarsfieldCopa De La Liga Profesional · Argentina | 0–1 | Copa De La Liga Profesional · Argentina |
| 2021-01-03 | AlbacetevMalagaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2021-01-03 | ParmavTorinoSerie A · Italy | 0–3 | Serie A · Italy |
| 2021-01-03 | Pacos FerreiravRio AvePrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2021-01-03 | OviedovMallorcaLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2021-01-03 | PanetolikosvOFI CreteSuper League · Greece | 2–1 | Super League · Greece |
| 2021-01-03 | OlympiakosvAEKSuper League · Greece | 3–0 | Super League · Greece |
| 2021-01-03 | Bayern MunichvMainzBundesliga · Germany | 5–2 | Bundesliga · Germany |
| 2021-01-03 | MaritimovBoavistaPrimeira Liga · Portugal | 0–0 | Primeira Liga · Portugal |
| 2021-01-03 | IndependientevArsenal SarandiCopa De La Liga Profesional · Argentina | 3–4 | Copa De La Liga Profesional · Argentina |
| 2021-01-03 | Erzgebirge AuevBraunschweig2. Bundesliga · Germany | 3–1 | 2. Bundesliga · Germany |
| 2021-01-03 | TondelavFamalicaoPrimeira Liga · Portugal | 1–0 | Primeira Liga · Portugal |
| 2021-01-03 | PortovMoreirensePrimeira Liga · Portugal | 3–0 | Primeira Liga · Portugal |
| 2021-01-03 | GenoavLazioSerie A · Italy | 1–1 | Serie A · Italy |
| 2021-01-03 | DortmundvWolfsburgBundesliga · Germany | 2–0 | Bundesliga · Germany |
| 2021-01-03 | JuventusvUdineseSerie A · Italy | 4–1 | Serie A · Italy |
| 2021-01-03 | RomavSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |