| 2016-11-21 | Din. BucurestivCFR ClujSuperliga · Romania | 0–2 | Superliga · Romania |
| 2016-11-21 | Viitorul ConstantavGaz Metan MediasSuperliga · Romania | 1–1 | Superliga · Romania |
| 2016-11-21 | Munich 1860vKaiserslautern2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-11-21 | TrabzonsporvAntalyasporSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2016-11-21 | Olimpo Bahia BlancavGimnasia L.P.Liga Profesional · Argentina | 0–0 | Liga Profesional · Argentina |
| 2016-11-21 | PueblavUNAM PumasLiga MX · Mexico | 0–3 | Liga MX · Mexico |
| 2016-11-21 | SilkeborgvEsbjergSuperliga · Denmark | 3–0 | Superliga · Denmark |
| 2016-11-21 | West BromvBurnleyPremier League · England | 4–0 | Premier League · England |
| 2016-11-20 | BolognavPalermoSerie A · Italy | 3–1 | Serie A · Italy |
| 2016-11-20 | Guadalajara ChivasvNecaxaLiga MX · Mexico | 1–1 | Liga MX · Mexico |
| 2016-11-20 | KayserisporvGenclerbirligiSüper Lig · Turkey | 0–2 | Süper Lig · Turkey |
| 2016-11-20 | TolucavSantos LagunaLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2016-11-20 | GremiovAmerica MGSerie A · Brazil | 3–0 | Serie A · Brazil |
| 2016-11-20 | AtalantavRomaSerie A · Italy | 2–1 | Serie A · Italy |
| 2016-11-20 | MonarcasvMonterreyLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2016-11-20 | AlavesvEspanolLa Liga · Spain | 0–1 | La Liga · Spain |
| 2016-11-20 | Union BerlinvStuttgart2. Bundesliga · Germany | 1–1 | 2. Bundesliga · Germany |
| 2016-11-20 | Athletico-PRvSport RecifeSerie A · Brazil | 2–0 | Serie A · Brazil |
| 2016-11-20 | Randers FCvViborgSuperliga · Denmark | 2–1 | Superliga · Denmark |
| 2016-11-20 | St PaulivFortuna Dusseldorf2. Bundesliga · Germany | 0–1 | 2. Bundesliga · Germany |
| 2016-11-20 | OdensevBrondbySuperliga · Denmark | 1–0 | Superliga · Denmark |
| 2016-11-20 | Young BoysvSionSuper League · Switzerland | 4–3 | Super League · Switzerland |
| 2016-11-20 | BelgranovSarmiento JuninLiga Profesional · Argentina | 1–2 | Liga Profesional · Argentina |
| 2016-11-20 | WaregemvAnderlechtPro League · Belgium | 3–2 | Pro League · Belgium |
| 2016-11-20 | Newells Old BoysvRiver PlateLiga Profesional · Argentina | 1–0 | Liga Profesional · Argentina |
| 2016-11-20 | Chapecoense-SCvSao PauloSerie A · Brazil | 2–0 | Serie A · Brazil |
| 2016-11-20 | HelsingborgvHalmstadAllsvenskan · Sweden | 1–2 | Allsvenskan · Sweden |
| 2016-11-20 | TenerifevUCAM MurciaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2016-11-20 | VitoriavFigueirenseSerie A · Brazil | 4–0 | Serie A · Brazil |
| 2016-11-20 | Arka GdyniavTermalica B-B.Ekstraklasa · Poland | 1–3 | Ekstraklasa · Poland |
| 2016-11-20 | EmpolivFiorentinaSerie A · Italy | 0–4 | Serie A · Italy |
| 2016-11-20 | MirandesvCordobaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2016-11-20 | MarseillevCaenLigue 1 · France | 1–0 | Ligue 1 · France |
| 2016-11-20 | PalmeirasvBotafogo RJSerie A · Brazil | 1–0 | Serie A · Brazil |
| 2016-11-20 | CrotonevTorinoSerie A · Italy | 0–2 | Serie A · Italy |
| 2016-11-20 | SalzburgvSK RapidBundesliga · Austria | 2–1 | Bundesliga · Austria |
| 2016-11-20 | MechelenvStandardPro League · Belgium | 2–1 | Pro League · Belgium |
| 2016-11-20 | Atl. RafaelavTalleres CordobaLiga Profesional · Argentina | 0–1 | Liga Profesional · Argentina |
| 2016-11-20 | LaziovGenoaSerie A · Italy | 3–1 | Serie A · Italy |
| 2016-11-20 | GetafevZaragozaLa Liga 2 · Spain | 1–0 | La Liga 2 · Spain |
| 2016-11-20 | KasimpasavKarabuksporSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2016-11-20 | Flamengo RJvCoritibaSerie A · Brazil | 2–2 | Serie A · Brazil |
| 2016-11-20 | AscolivPerugiaSerie B · Italy | 2–2 | Serie B · Italy |
| 2016-11-20 | Tigres UANLvQueretaroLiga MX · Mexico | 1–2 | Liga MX · Mexico |
| 2016-11-20 | CharleroivLokerenPro League · Belgium | 2–1 | Pro League · Belgium |
| 2016-11-20 | AjaxvNijmegenEredivisie · Netherlands | 5–0 | Eredivisie · Netherlands |
| 2016-11-20 | GuingampvBordeauxLigue 1 · France | 1–1 | Ligue 1 · France |
| 2016-11-20 | Santa CruzvAtletico-MGSerie A · Brazil | 3–3 | Serie A · Brazil |
| 2016-11-20 | FeyenoordvZwolleEredivisie · Netherlands | 3–0 | Eredivisie · Netherlands |
| 2016-11-20 | DresdenvGreuther Furth2. Bundesliga · Germany | 2–1 | 2. Bundesliga · Germany |