| 2022-01-09 | VeneziavMilanSerie A · Italy | 0–3 | Serie A · Italy |
| 2022-01-09 | Sp BragavFamalicaoPrimeira Liga · Portugal | 2–2 | Primeira Liga · Portugal |
| 2022-01-09 | BochumvWolfsburgBundesliga · Germany | 1–0 | Bundesliga · Germany |
| 2022-01-09 |  Cameroonv Burkina FasoAfrican Cup of Nations | 2–1 | African Cup of Nations |
| 2022-01-09 | BrestvNiceLigue 1 · France | 0–3 | Ligue 1 · France |
| 2022-01-09 | MetzvStrasbourgLigue 1 · France | 0–2 | Ligue 1 · France |
| 2022-01-09 | RizesporvBesiktasSüper Lig · Turkey | 2–2 | Süper Lig · Turkey |
| 2022-01-09 | VeronavSalernitanaSerie A · Italy | 1–2 | Serie A · Italy |
| 2022-01-09 | PonferradinavZaragozaLa Liga 2 · Spain | 0–0 | La Liga 2 · Spain |
| 2022-01-09 | RomavJuventusSerie A · Italy | 3–4 | Serie A · Italy |
| 2022-01-09 | KonyasporvSivassporSüper Lig · Turkey | 0–1 | Süper Lig · Turkey |
| 2022-01-09 | BelenensesvAroucaPrimeira Liga · Portugal | 2–1 | Primeira Liga · Portugal |
| 2022-01-09 | GenoavSpeziaSerie A · Italy | 0–1 | Serie A · Italy |
| 2022-01-09 | MalagavSp GijonLa Liga 2 · Spain | 2–2 | La Liga 2 · Spain |
| 2022-01-09 | PortimonensevMaritimoPrimeira Liga · Portugal | 1–2 | Primeira Liga · Portugal |
| 2022-01-09 | UdinesevAtalantaSerie A · Italy | 2–6 | Serie A · Italy |
| 2022-01-09 | LyonvParis SGLigue 1 · France | 1–1 | Ligue 1 · France |
| 2022-01-09 | VillarrealvAth MadridLa Liga · Spain | 2–2 | La Liga · Spain |
| 2022-01-09 | HerthavFC KolnBundesliga · Germany | 1–3 | Bundesliga · Germany |
| 2022-01-09 | GoztepvAntalyasporSüper Lig · Turkey | 4–0 | Süper Lig · Turkey |
| 2022-01-09 | SevillavGetafeLa Liga · Spain | 1–0 | La Liga · Spain |
| 2022-01-09 | VallecanovBetisLa Liga · Spain | 1–1 | La Liga · Spain |
| 2022-01-09 | BenficavPacos FerreiraPrimeira Liga · Portugal | 2–0 | Primeira Liga · Portugal |
| 2022-01-09 |  Ethiopiav Cape VerdeAfrican Cup of Nations | 0–1 | African Cup of Nations |
| 2022-01-09 | OsasunavCadizLa Liga · Spain | 2–0 | La Liga · Spain |
| 2022-01-08 | Pau FCvRodezLigue 2 · France | 4–0 | Ligue 2 · France |
| 2022-01-08 | KasimpasavHataysporSüper Lig · Turkey | 3–1 | Süper Lig · Turkey |
| 2022-01-08 | ForfarvStranraerLeague Two · Scotland | 3–2 | League Two · Scotland |
| 2022-01-08 | Greuther FurthvStuttgartBundesliga · Germany | 0–0 | Bundesliga · Germany |
| 2022-01-08 | Ein FrankfurtvDortmundBundesliga · Germany | 2–3 | Bundesliga · Germany |
| 2022-01-08 | CarlislevBradfordLeague Two · England | 2–0 | League Two · England |
| 2022-01-08 | ValenciennesvGuingampLigue 2 · France | 1–1 | Ligue 2 · France |
| 2022-01-08 | OFI CretevGianninaSuper League · Greece | 1–1 | Super League · Greece |
| 2022-01-08 | ClydevCove RangersLeague One · Scotland | 0–1 | League One · Scotland |
| 2022-01-08 | CartagenavHuescaLa Liga 2 · Spain | 0–3 | La Liga 2 · Spain |
| 2022-01-08 | Chengdu RongchengvDalian ProSuper League · China | 1–1 | Super League · China |
| 2022-01-08 | BromleyvSolihullNational League · England | 2–1 | National League · England |
| 2022-01-08 | IbizavAlcorconLa Liga 2 · Spain | 6–2 | La Liga 2 · Spain |
| 2022-01-08 | Qingdao FCvZhejiang ProfessionalSuper League · China | 0–1 | Super League · China |
| 2022-01-08 | GillinghamvIpswichLeague One · England | 0–4 | League One · England |
| 2022-01-08 | Albion RvsvStenhousemuirLeague Two · Scotland | 1–2 | League Two · Scotland |
| 2022-01-08 | FreiburgvBielefeldBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2022-01-08 | WeymouthvSouthendNational League · England | 0–1 | National League · England |
| 2022-01-08 | AyrvArbroathChampionship · Scotland | 1–0 | Championship · Scotland |
| 2022-01-08 | JuarezvNecaxaLiga MX · Mexico | 2–1 | Liga MX · Mexico |
| 2022-01-08 | TorquayvDag and RedNational League · England | 2–2 | National League · England |
| 2022-01-08 | Le HavrevSochauxLigue 2 · France | 0–1 | Ligue 2 · France |
| 2022-01-08 | StevenagevWalsallLeague Two · England | 3–1 | League Two · England |
| 2022-01-08 | LeverkusenvUnion BerlinBundesliga · Germany | 2–2 | Bundesliga · Germany |
| 2022-01-08 | Airdrie UtdvEast FifeLeague One · Scotland | 3–0 | League One · Scotland |