| 2022-01-12 | Zhejiang ProfessionalvQingdao FCSuper League · China | 0–0 | Super League · China |
| 2022-01-12 |  Tunisiav MaliAfrican Cup of Nations | 0–1 | African Cup of Nations |
| 2022-01-12 |  Equatorial Guineav Ivory CoastAfrican Cup of Nations | 0–1 | African Cup of Nations |
| 2022-01-12 | ApollonvOFI CreteSuper League · Greece | 0–3 | Super League · Greece |
| 2022-01-12 | West HamvNorwichPremier League · England | 2–0 | Premier League · England |
| 2022-01-12 | Dalian ProvChengdu RongchengSuper League · China | 0–1 | Super League · China |
| 2022-01-12 | CrewevCharltonLeague One · England | 2–1 | League One · England |
| 2022-01-12 |  Mauritaniav GambiaAfrican Cup of Nations | 0–1 | African Cup of Nations |
| 2022-01-12 | PAOKvPanetolikosSuper League · Greece | 2–0 | Super League · Greece |
| 2022-01-11 | Kings LynnvNotts CountyNational League · England | 2–4 | National League · England |
| 2022-01-11 | SunderlandvLincolnLeague One · England | 1–3 | League One · England |
| 2022-01-11 | SalfordvTranmereLeague Two · England | 1–1 | League Two · England |
| 2022-01-11 | SouthamptonvBrentfordPremier League · England | 4–1 | Premier League · England |
| 2022-01-11 | CagliarivBolognaSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-01-11 |  Nigeriav EgyptAfrican Cup of Nations | 1–0 | African Cup of Nations |
| 2022-01-11 |  Sudanv Guinea-BissauAfrican Cup of Nations | 0–0 | African Cup of Nations |
| 2022-01-11 | Forest GreenvColchesterLeague Two · England | 2–0 | League Two · England |
| 2022-01-11 | AltrinchamvStockportNational League · England | 1–4 | National League · England |
| 2022-01-11 | SouthendvYeovilNational League · England | 2–1 | National League · England |
| 2022-01-11 | UNAM PumasvTolucaLiga MX · Mexico | 5–0 | Liga MX · Mexico |
| 2022-01-11 | Boreham WoodvWealdstoneNational League · England | 1–0 | National League · England |
| 2022-01-11 | ReadingvFulhamChampionship · England | 0–7 | Championship · England |
| 2022-01-11 | Milton Keynes DonsvAFC WimbledonLeague One · England | 1–0 | League One · England |
| 2022-01-11 |  Algeriav Sierra LeoneAfrican Cup of Nations | 0–0 | African Cup of Nations |
| 2022-01-11 | MansfieldvSwindonLeague Two · England | 3–2 | League Two · England |
| 2022-01-11 | BoltonvWycombeLeague One · England | 0–2 | League One · England |
| 2022-01-11 | HalifaxvGrimsbyNational League · England | 1–0 | National League · England |
| 2022-01-10 | OviedovEibarLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |
| 2022-01-10 |  Guineav MalawiAfrican Cup of Nations | 1–0 | African Cup of Nations |
| 2022-01-10 | EspanolvElcheLa Liga · Spain | 1–2 | La Liga · Spain |
| 2022-01-10 | FenerbahcevAd. DemirsporSüper Lig · Turkey | 1–2 | Süper Lig · Turkey |
| 2022-01-10 | Guadalajara ChivasvMazatlan FCLiga MX · Mexico | 3–0 | Liga MX · Mexico |
| 2022-01-10 | TorinovFiorentinaSerie A · Italy | 4–0 | Serie A · Italy |
| 2022-01-10 |  Comorosv GabonAfrican Cup of Nations | 0–1 | African Cup of Nations |
| 2022-01-10 |  Senegalv ZimbabweAfrican Cup of Nations | 1–0 | African Cup of Nations |
| 2022-01-10 | Gil VicentevGuimaraesPrimeira Liga · Portugal | 3–2 | Primeira Liga · Portugal |
| 2022-01-10 |  Moroccov GhanaAfrican Cup of Nations | 1–0 | African Cup of Nations |
| 2022-01-09 | LugovMirandesLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-09 | NapolivSampdoriaSerie A · Italy | 1–0 | Serie A · Italy |
| 2022-01-09 | MonterreyvQueretaroLiga MX · Mexico | 0–0 | Liga MX · Mexico |
| 2022-01-09 | Volos NFCvPanathinaikosSuper League · Greece | 3–1 | Super League · Greece |
| 2022-01-09 | AlavesvAth BilbaoLa Liga · Spain | 0–0 | La Liga · Spain |
| 2022-01-09 | KayserisporvAltaySüper Lig · Turkey | 1–0 | Süper Lig · Turkey |
| 2022-01-09 | ClermontvReimsLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-01-09 | GironavFuenlabradaLa Liga 2 · Spain | 2–1 | La Liga 2 · Spain |
| 2022-01-09 | EmpolivSassuoloSerie A · Italy | 1–5 | Serie A · Italy |
| 2022-01-09 | Cruz AzulvClub TijuanaLiga MX · Mexico | 2–0 | Liga MX · Mexico |
| 2022-01-09 | IntervLazioSerie A · Italy | 2–1 | Serie A · Italy |
| 2022-01-09 | Nantesv MonacoLigue 1 · France | 0–0 | Ligue 1 · France |
| 2022-01-09 | Las PalmasvAlmeriaLa Liga 2 · Spain | 1–1 | La Liga 2 · Spain |